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Neuroscience

D-Index
85
Citations
25712
World Ranking
1336
National Ranking
148

Biology and Biochemistry

D-Index
85
Citations
25702
World Ranking
3154
National Ranking
238

Overview

Kristjan R. Jessen is affiliated with University College London in the United Kingdom. Their research primarily focuses on neuroscience, medicine, and biochemistry, genetics, and molecular biology. Within these disciplines, they specialize further in cellular and molecular neuroscience, developmental neuroscience, molecular biology, surgery, and mental health.

The main topics covered in Kristjan R. Jessen's work include nerve injury and regeneration, neurogenesis and neuroplasticity mechanisms, signaling pathways in disease, axon guidance and neuronal signaling, cancer, stress, anesthesia, immune response, phagocytosis and immune regulation, and pancreatic function and diabetes.

Frequent coauthors collaborating with Kristjan R. Jessen include Rhona Mirsky, Laura Wagstaff, Jose A. Gomez-Sanchez, Shaline V. Fazal, and Georg Otto.

Notable recent papers authored or coauthored by Kristjan R. Jessen include:

  • "Reprogrammed Schwann Cells Organize into Dynamic Tracks that Promote Pancreatic Cancer Invasion," 2022, Cancer Discovery
  • "Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun," 2021, eLife
  • "The Role of c-Jun and Autocrine Signaling Loops in the Control of Repair Schwann Cells and Regeneration," 2022, Frontiers in Cellular Neuroscience
  • "Characterising cellular and molecular features of human peripheral nerve degeneration," 2020, Acta Neuropathologica Communications
  • "Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun," 2020, bioRxiv (Cold Spring Harbor Laboratory)

Kristjan R. Jessen's publications have appeared in multiple peer-reviewed venues, including Cancer Discovery, eLife, Frontiers in Cellular Neuroscience, Acta Neuropathologica Communications, and bioRxiv.

Best Publications

  • The origin and development of glial cells in peripheral nerves

    Kristjan R. Jessen;Rhona Mirsky

  • The repair Schwann cell and its function in regenerating nerves

    K. R. Jessen;R. Mirsky

  • c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

    Peter J. Arthur-Farraj;Morwena Latouche;Daniel K. Wilton;Susanne Quintes

  • Schwann Cells: Development and Role in Nerve Repair

    Kristján R. Jessen;Rhona Mirsky;Alison C. Lloyd

  • Negative regulation of myelination: relevance for development, injury, and demyelinating disease.

    Kristján R. Jessen;Rhona Mirsky

  • Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors.

    Z. Dong;A. Brennan;N. Liu;Y. Yarden

  • Glial cells in the enteric nervous system contain glial fibrillary acidic protein

    Kristjan R. Jessen;Rhona Mirsky

  • The effects of cAMP on differentiation of cultured Schwann cells: progression from an early phenotype (04+) to a myelin phenotype (P0+, GFAP-, N-CAM-, NGF-receptor-) depends on growth inhibition.

    L Morgan;K R Jessen;R Mirsky

  • Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF

    George K. Tofaris;Paul H. Patterson;Kristjan R. Jessen;Rhona Mirsky

  • The Success and Failure of the Schwann Cell Response to Nerve Injury.

    Kristjan R. Jessen;Rhona Mirsky

  • Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

    Jose A. Gomez-Sanchez;Lucy Carty;Marta Iruarrizaga-Lejarreta;Marta Palomo-Irigoyen

  • c-Jun is a negative regulator of myelination

    DB Parkinson;A Bhaskaran;P Arthur-Farraj;LA Noon

  • Glial cells.

    Unknown

  • Schwann cells and their precursors emerge as major regulators of nerve development.

    Kristjan R Jessen;Rhona Mirsky

  • GABA may be a neurotransmitter in the vertebrate peripheral nervous system

    Kristján R. Jessen;Rhona Mirsky;Marion E. Dennison;Geoffrey Burnstock

  • Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths.

    Eric Parmantier;Bruce Lynn;Durward Lawson;Mark Turmaine

  • Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity

    Ashwin Woodhoo;Maria B Duran Alonso;Anna Droggiti;Mark Turmaine

  • The Schwann cell precursor and its fate: a study of cell death and differentiation during gliogenesis in rat embryonic nerves.

    K.R. Jessen;A. Brennan;L. Morgan;R. Mirsky

  • Schwann cell precursors and their development.

    Kristjan R. Jessen;Rhona Mirsky

  • Three markers of adult non-myelin-forming Schwann cells, 217c(Ran-1), A5E3 and GFAP: development and regulation by neuron-Schwann cell interactions

    K. R. Jessen;L. Morgan;H. J. S. Stewart;R. Mirsky

  • Developing Schwann Cells Acquire the Ability to Survive without Axons by Establishing an Autocrine Circuit Involving Insulin-Like Growth Factor, Neurotrophin-3, and Platelet-Derived Growth Factor-BB

    Carola Meier;Eric Parmantier;Angela Brennan;Rhona Mirsky

Frequent Co-Authors

Rhona Mirsky
Rhona Mirsky University College London
Geoffrey Burnstock
Geoffrey Burnstock University College London
Helen Stewart
Helen Stewart Brighton and Sussex Medical School
Axel Behrens
Axel Behrens Imperial College London
Dies Meijer
Dies Meijer University of Edinburgh
Mitsuhiro Osame
Mitsuhiro Osame Kagoshima University
Lawrence Wrabetz
Lawrence Wrabetz University at Buffalo, State University of New York
Patrick M. Wood
Patrick M. Wood University of Miami
Timothy J. Aitman
Timothy J. Aitman University of Edinburgh
Frank Baas
Frank Baas Leiden University Medical Center

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