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Giacomo P. Comi

Giacomo P. Comi

D-Index & Metrics

Genetics

D-Index
94
Citations
29713
World Ranking
937
National Ranking
11

Medicine

D-Index
108
Citations
40057
World Ranking
6038
National Ranking
189

Overview

Giacomo P. Comi is affiliated with the University of Milan in Italy and has a research profile focused on medicine and biochemistry, genetics, and molecular biology. Their work emphasizes molecular biology, neurology, genetics, cellular and molecular neuroscience, as well as cardiology and cardiovascular medicine.

Their scientific output covers several main topics, including:

  • Neurogenetic and Muscular Disorders Research
  • Muscle Physiology and Disorders
  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Amyotrophic Lateral Sclerosis Research
  • Cardiomyopathy and Myosin Studies
  • Parkinson's Disease Mechanisms and Treatments

Among the recent papers associated with Giacomo P. Comi's research are the following:

  • The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer's Disease and Parkinson's Disease, 2020, Molecular Neurobiology
  • Onasemnogene abeparvovec gene therapy for symptomatic infantile-onset spinal muscular atrophy type 1 (STR1VE-EU): an open-label, single-arm, multicentre, phase 3 trial, 2021, The Lancet Neurology
  • Neural Stem Cell Transplantation for Neurodegenerative Diseases, 2020, International Journal of Molecular Sciences
  • Nusinersen safety and effects on motor function in adult spinal muscular atrophy type 2 and 3, 2020, Journal of Neurology Neurosurgery & Psychiatry
  • TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models, 2021, Cellular and Molecular Gastroenterology and Hepatology

Giacomo P. Comi frequently collaborates with a number of researchers, including:

  • Stefania Corti
  • Dario Ronchi
  • Megi Meneri
  • Francesca Magri
  • Nereo Bresolin

Their research is often published in several notable venues with multiple contributions in each, such as:

  • Frontiers in Neurology (17 publications)
  • Neurological Sciences (15 publications)
  • Neuromuscular Disorders (13 publications)
  • Neurology (11 publications)
  • Journal of the Neurological Sciences (9 publications)

This profile reflects Giacomo P. Comi's engagement in interdisciplinary studies at the intersection of neurological and molecular biological research, with a particular emphasis on neurodegenerative and muscular disorders and their genetic and mitochondrial underpinnings.

Best Publications

  • Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria.

    Johannes N. Spelbrink;Fang Yuan Li;Valeria Tiranti;Kaisu Nikali

  • Role of Adenine Nucleotide Translocator 1 in mtDNA Maintenance

    Jyrki Kaukonen;Jukka K. Juselius;Valeria Tiranti;Aija Kyttälä

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Randomized controlled trial of intravenous immunoglobulin versus oral prednisolone in chronic inflammatory demyelinating polyradiculoneuropathy

    R Hughes;Peter Van den Bergh;S Bensa;H Willison

  • Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

    Wouter van Rheenen;Aleksey Shatunov;Annelot M. Dekker;Russell L. McLaughlin

  • Ataluren treatment of patients with nonsense mutation dystrophinopathy

    Katharine Bushby;Richard Finkel;Brenda Wong;Richard Barohn

  • Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis.

    Massimo Filippi;M. Bozzali;M. Rovaris;O. Gonen

  • EEG coherence in Alzheimer's disease.

    T. Locatelli;M. Cursi;D. Liberati;M. Franceschi

  • Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study.

    G Giancarlo Comi;A. Pulizzi;Marco Rovaris;O. Abramsky

  • Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis

    M. Rovaris;Massimo Filippi;M. Falautano;L. Minicucci

  • Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis

    M Cercignani;M Bozzali;G Iannucci;G Comi

  • Mutations of mitochondrial DNA polymerase γA are a frequent cause of autosomal dominant or recessive progressive external ophthalmoplegia

    Eleonora Lamantea;Valeria Tiranti;Andreina Bordoni;Antonio Toscano

  • Cytochrome c Oxidase subunit I microdeletion in a patient with motor neuron disease

    Giacomo P. Comi;Andreina Bordoni;Sabrina Salani;Liliana Franceschina

  • Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

    Matteo Fumagalli;Uberto Pozzoli;Rachele Cagliani;Giacomo P. Comi

  • Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis

    Marina Scarlato;Stefano Carlo Previtali;Marinella Carpo;Davide Pareyson

  • Physiopathology and treatment of fatigue in multiple sclerosis

    G. Comi;L. Leocani;P. Rossi;B. Colombo

  • Autologous transplantation of muscle-derived CD133(+) stem cells in Duchenne muscle patients

    Yvan Torrente;M. Belicchi;C. Marchesi;G. D'Antona

  • Comparison of MS clinical phenotypes using conventional and magnetization transfer MRI

    Massimo Filippi;G. Iannucci;C. Tortorella;L. Minicucci

  • Changes in the normal appearing brain tissue and cognitive impairment in multiple sclerosis

    M Filippi;C Tortorella;M Rovaris;M Bozzali

  • Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi

Frequent Co-Authors

Nereo Bresolin
Nereo Bresolin University of Milan
Stefania Corti
Stefania Corti University of Milan
Manuela Sironi
Manuela Sironi University of Turin
Claudio Bruno
Claudio Bruno Istituto Giannina Gaslini
Enrico Bertini
Enrico Bertini Bambino Gesù Children's Hospital
Eugenio Mercuri
Eugenio Mercuri Catholic University of the Sacred Heart
Marina Mora
Marina Mora Istituto Neurologico Carlo Besta
Corrado Angelini
Corrado Angelini University of Padua
Elio Scarpini
Elio Scarpini University of Milan
Massimo Zeviani
Massimo Zeviani University of Padua

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