What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Transcription factor, Molecular biology, Gene, Chromatin and Nucleosome.
Transcription factor is frequently linked to Myelin in his study.
His research in Myelin intersects with topics in Schwann cell and Cellular differentiation.
The various areas that he examines in his Molecular biology study include Protein domain, NAB2 and Cell biology.
In his research on the topic of Cell biology, Transactivation is strongly related with Pho4.
His Gene study is concerned with the field of Genetics as a whole.
His most cited work include:
- NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. (324 citations)
- Fluoro ketone inhibitors of hydrolytic enzymes. (310 citations)
- EGR2 Mutations in Inherited Neuropathies Dominant-Negatively Inhibit Myelin Gene Expression (232 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Cell biology, Transcription factor, Molecular biology, Schwann cell and Myelin.
The study incorporates disciplines such as Saccharomyces cerevisiae, Psychological repression, Mi-2/NuRD complex, Chromatin and Histone methylation in addition to Cell biology.
As part of his inquiry into Genetics and Gene, he is doing Transcription factor research.
His study looks at the intersection of Molecular biology and topics like Early Growth Response Protein 2 with Phenotype.
His Schwann cell research is multidisciplinary, incorporating perspectives in Regulation of gene expression, Schwann cell differentiation, Nerve injury and Neuroglia.
His work on Myelin protein zero as part of general Myelin study is frequently connected to Cell type, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
He most often published in these fields:
- Cell biology (41.27%)
- Transcription factor (30.16%)
- Molecular biology (26.98%)
What were the highlights of his more recent work (between 2016-2021)?
- Cell biology (41.27%)
- Schwann cell (26.19%)
- Myelin (23.81%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cell biology, Schwann cell, Myelin, Gene duplication and Gene.
His studies in Cell biology integrate themes in fields like Gene knockout, microRNA, Neuroscience and Myelin protein zero.
His work deals with themes such as SOX10, Regeneration and c-jun, which intersect with Schwann cell.
His Myelin study combines topics from a wide range of disciplines, such as Stem cell, Nerve injury, Neuregulin 1 and Neural crest.
To a larger extent, John Svaren studies Genetics with the aim of understanding Gene.
His Transcription factor study integrates concerns from other disciplines, such as Structural variation and Epigenetics.
Between 2016 and 2021, his most popular works were:
- PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models (62 citations)
- A mutation in the Tubb4a gene leads to microtubule accumulation with hypomyelination and demyelination (23 citations)
- Myelin protein zero mutations and the unfolded protein response in Charcot Marie Tooth disease type 1B (17 citations)
In his most recent research, the most cited papers focused on:
John Svaren spends much of his time researching Cell biology, Schwann cell, Myelin, Gene duplication and Phenotype.
John Svaren combines subjects such as Cell cycle and ER retention, Mutant with his study of Cell biology.
John Svaren interconnects microRNA, Nerve injury, Neuregulin 1 and SOX10 in the investigation of issues within Schwann cell.
His research integrates issues of Mutation, Point mutation and Leukodystrophy in his study of Myelin.
His biological study spans a wide range of topics, including Regulation of gene expression, Chromatin immunoprecipitation and Gene knockdown.
Genetics covers John Svaren research in Phenotype.
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