What is he best known for?
The fields of study he is best known for:
Gilbert de Murcia focuses on Poly ADP ribose polymerase, Molecular biology, DNA damage, Base excision repair and DNA repair. His study of Poly glycohydrolase is a part of Poly ADP ribose polymerase. His studies deal with areas such as Complementary DNA, Poly [ADP-Ribose] Polymerase 2, PARG and Cell biology as well as Poly glycohydrolase.
His Molecular biology study incorporates themes from Cell culture, Nitric oxide synthase, Inflammation, Mutant and Programmed cell death. His DNA damage study frequently draws connections to adjacent fields such as DNA ligase. His work deals with themes such as Genome instability and Homologous recombination, which intersect with Base excision repair.
His most cited work include:
- Poly(ADP-ribose): novel functions for an old molecule. (1477 citations)
- The PARP superfamily. (1132 citations)
- Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells (899 citations)
What are the main themes of his work throughout his whole career to date?
Gilbert de Murcia spends much of his time researching Poly ADP ribose polymerase, Molecular biology, Biochemistry, Polymerase and DNA damage. His Poly ADP ribose polymerase research is multidisciplinary, incorporating elements of Apoptosis, DNA repair and Cell biology. His research on Molecular biology also deals with topics like
- Base excision repair and related Nucleotide excision repair and Homologous recombination,
- Mutant together with Programmed cell death.
In the field of Biochemistry, his study on Chromatin, Complementary DNA and Ribose overlaps with subjects such as DNA polymerase II and DNA clamp. His research in Polymerase intersects with topics in Gene expression, Recombinant DNA and NAD+ kinase. The DNA damage study combines topics in areas such as Cell cycle and Poly Polymerase Inhibitor.
He most often published in these fields:
- Poly ADP ribose polymerase (63.53%)
- Molecular biology (52.94%)
- Biochemistry (42.35%)
What were the highlights of his more recent work (between 2003-2013)?
- Poly ADP ribose polymerase (63.53%)
- Molecular biology (52.94%)
- DNA damage (35.29%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Poly ADP ribose polymerase, Molecular biology, DNA damage, Cell biology and DNA. His Poly ADP ribose polymerase study deals with the bigger picture of Biochemistry. His Molecular biology research incorporates themes from Apoptosis, Telomerase, DNA repair, Telomere and Transcription.
His Base excision repair study, which is part of a larger body of work in DNA damage, is frequently linked to Ataxia Telangiectasia Mutated Proteins, bridging the gap between disciplines. Gilbert de Murcia has researched Cell biology in several fields, including Poly glycohydrolase, Transfection and NAD+ kinase, Enzyme. His work on Polymerase as part of general DNA research is often related to NPM1, RNA polymerase I and Nucleolus, thus linking different fields of science.
Between 2003 and 2013, his most popular works were:
- Poly(ADP-ribose): novel functions for an old molecule. (1477 citations)
- The PARP superfamily. (1132 citations)
- Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells. (206 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Cell biology, Poly ADP ribose polymerase, Molecular biology, DNA damage and Homologous recombination. He has included themes like Poly glycohydrolase, DNA repair, Histone, Cathepsin B and NAD+ kinase in his Cell biology study. His research on Poly ADP ribose polymerase often connects related areas such as Ribose.
His work carried out in the field of Molecular biology brings together such families of science as Retinoic acid receptor, Promoter, Chromatin immunoprecipitation and Chromatin. His biological study spans a wide range of topics, including Autophagy, Cell, PARP inhibitor, Transfection and Programmed cell death. The study incorporates disciplines such as Base excision repair, DNA ligase and Mutation in addition to Homologous recombination.
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