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Biology and Biochemistry

D-Index
57
Citations
8976
World Ranking
14077
National Ranking
16

Overview

Ewa Sikora is affiliated with the Polish Academy of Sciences in Poland and has concentrated research efforts in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work prominently intersects molecular biology, physiology, immunology, epidemiology, and nutrition and dietetics.

The main topics covered by Sikora's research include telomeres, telomerase, and senescence; DNA repair mechanisms; neutrophil, myeloperoxidase, and oxidative mechanisms; nutritional studies and diet; genetics, aging, and longevity in model organisms; autophagy in disease and therapy; and antioxidant activity and oxidative stress.

Notable recent publications authored or coauthored by Sikora include:

  • Cellular Senescence in Brain Aging, 2021, Frontiers in Aging Neuroscience
  • Guidelines for minimal information on cellular senescence experimentation in vivo, 2024, Cell
  • Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains, 2021, Scientific Reports
  • A common signature of cellular senescence; does it exist?, 2021, Ageing Research Reviews
  • Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile, 2022, Aging

Sikora frequently collaborates with several researchers, including Claudio Franceschi, Efstathios S. Gonos, Martijn E.T. Dollé, Tilman Grune, and Miriam Capri, with each collaboration reflected in over 20 joint publications.

Their research is published largely in venues specializing in aging and molecular science, such as GeroScience, Mechanisms of Ageing and Development, International Journal of Molecular Sciences, The Journals of Gerontology Series A, and Aging.

Best Publications

  • Sirtuins, a promising target in slowing down the ageing process

    Wioleta Grabowska;Ewa Sikora;Anna Bielak-Zmijewska

  • Impact of cellular senescence signature on ageing research.

    Ewa Sikora;Thomas Arendt;Martin Bennett;Masashi Narita

  • MARK-AGE biomarkers of ageing

    Alexander Bürkle;María Moreno-Villanueva;Jürgen Bernhard;María Blasco

  • Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

    Marian Beekman;Hélène Blanché;Markus Perola;Anti Hervonen

  • Cellular Senescence in Brain Aging.

    Ewa Sikora;Anna Bielak-Zmijewska;Magdalena Dudkowska;Adam Krzystyniak

  • Curcumin, inflammation, ageing and age-related diseases

    E Sikora;Giovanni Scapagnini;Mario Barbagallo

  • Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells.

    Malgorzata A. Sliwinska;Grazyna Mosieniak;Kamila Wolanin;Aneta Babik

  • Apoptosis-like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes

    Ewa Jaruga;Stefano Salvioli;Jurek Dobrucki;Sławomir Chrul

  • A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells.

    Katarzyna Piwocka;Krzysztof Zabłocki;Mariusz R. Więckowski;Janusz Skierski

  • Curcumin in Cell Death Processes: A Challenge for CAM of Age-Related Pathologies

    S. Salvioli;E. Sikora;E. L. Cooper;C. Franceschi

  • What evidence is there for the existence of individual genes with antagonistic pleiotropic effects

    Armand M. Leroi;Andrzej Bartke;Giovanna De Benedictis;Claudio Franceschi

  • Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment

    Ewa Sikora;Anna Bielak-Zmijewska;Katarzyna Piwocka;Skierski Janusz

  • Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy.

    Grazyna Mosieniak;Marek Adamowicz;Olga Alster;Hubert Jaskowiak

  • Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence

    Grazyna Mosieniak;Malgorzata A. Sliwinska;Olga Alster;Anna Strzeszewska

  • A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta

    Anna Bielak-Zmijewska;Maciej Wnuk;Dorota Przybylska;Wioleta Grabowska

  • Is senescence-associated β-galactosidase a marker of neuronal senescence?

    Malgorzata Piechota;Piotr Sunderland;Adrianna Wysocka;Maria Nalberczak

  • Curcumin Affects Components of the Chromosomal Passenger Complex and Induces Mitotic Catastrophe in Apoptosis-Resistant Bcr-Abl-Expressing Cells

    Kamila Wolanin;Adriana Magalska;Grażyna Mosieniak;Rut Klinger

  • The Role of Curcumin in the Modulation of Ageing

    Anna Bielak-Zmijewska;Wioleta Grabowska;Agata Ciolko;Agnieszka Bojko

  • Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

    Claudio Franceschi;Vladyslav Bezrukov;Hélène Blanché;Lars Bolund

  • Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from

    Grazyna Mosieniak;Malgorzata A. Sliwinska;Olga Alster;Anna Strzeszewska

Frequent Co-Authors

Claudio Franceschi
Claudio Franceschi University of Bologna
Efstathios S. Gonos
Efstathios S. Gonos National Hellenic Research Foundation
Alexander Bürkle
Alexander Bürkle University of Konstanz
Olivier Toussaint
Olivier Toussaint University of Namur
Tilman Grune
Tilman Grune University of Potsdam
Beatrix Grubeck-Loebenstein
Beatrix Grubeck-Loebenstein University of Innsbruck
Miriam Capri
Miriam Capri University of Bologna
Mikko Hurme
Mikko Hurme Tampere University
Marco Malavolta
Marco Malavolta Advanced Technology Center
Giuseppe Passarino
Giuseppe Passarino University of Calabria

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