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Immunology

D-Index
81
Citations
21006
World Ranking
1585
National Ranking
11

Medicine

D-Index
82
Citations
21201
World Ranking
16277
National Ranking
188

Overview

Mikko Hurme is affiliated with Tampere University in Finland and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research focuses primarily on molecular biology and genetics, with additional work involving cardiology, cancer research, and epidemiology.

Their scholarly output includes significant publications in several research topics, including:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Chromosomal and Genetic Variations
  • Genetic Associations and Epidemiology
  • Genetic Syndromes and Imprinting
  • Genomics and Phylogenetic Studies
  • Animal Virus Infections Studies

Frequent co-authors collaborating with Hurme encompass:

  • Terho Lehtimäki
  • Claudio Franceschi
  • P. Eline Slagboom
  • Efstathios S. Gonos
  • Ewa Sikora

The scientist has published multiple research papers in notable venues such as Scientific Reports, Immunity & Ageing, Nature Communications, GeroScience, and The Journals of Gerontology Series A. Noteworthy recent papers include:

  • "DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases," 2022, Nature Communications
  • "Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains," 2021, Scientific Reports
  • "DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures," 2021, Clinical Epigenetics
  • "Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure," 2020, Hypertension
  • "BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for body mass index," 2022, Journal of Internal Medicine

Hurme's body of work often explores the relationship between epigenetic mechanisms and various physiological and pathological conditions, including inflammation, metabolic profiles, blood pressure regulation, and aging processes. Their interdisciplinary approach integrates molecular data with epidemiological insights.

Best Publications

  • Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro.

    S Santtila;K Savinainen;M Hurme

  • IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes.

    Mikko Hurme;Sari Santtila

  • Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG.

    T Pessi;Y Sütas;M Hurme;E Isolauri

  • A meta-analysis of genome-wide association studies identifies multiple longevity genes

    Joris Deelen;Joris Deelen;Daniel S. Evans;Dan E. Arking;Niccolò Tesi;Niccolò Tesi

  • Mitochondrial DNA polymorphisms associated with longevity in a Finnish population.

    Anna-Kaisa Niemi;Antti Hervonen;Mikko Hurme;Pekka J. Karhunen

  • MARK-AGE biomarkers of ageing

    Alexander Bürkle;María Moreno-Villanueva;Jürgen Bernhard;María Blasco

  • Increased plasma levels of pro- and anti-inflammatory cytokines in patients with febrile seizures.

    Miia Virta;Mikko Hurme;Merja Helminen

  • Down‐Regulation of Anti‐CD3 Antibody‐Induced IL‐4 Production by Bovine Caseins Hydrolysed with Lactobacillus GG‐Derived Enzymes

    Y. Sütas;M. Hurme;E. Isolauri

  • Interleukin-6 and interleukin-1 receptor antagonist in cerebrospinal fluid from patients with recent tonic-clonic seizures.

    J Peltola;J Palmio;Laura Korhonen;J Suhonen

  • Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.

    Giovanni Fiorito;Cathal McCrory;Oliver Robinson;Cristian Carmeli

  • FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders.

    Jenni M. Lehtonen;Saara Forsström;Emanuela Bottani;Carlo Viscomi

  • Retinoic acid activates interferon regulatory factor-1 gene expression in myeloid cells

    S Matikainen;T Ronni;M Hurme;R Pine

  • Polymorphism of the interleukin-10 gene is associated with susceptibility to Epstein-Barr virus infection.

    Merja Helminen;Nina Lahdenpohja;Mikko Hurme

  • CMV and Immunosenescence: from basics to clinics

    Rafael Solana;Raquel Tarazona;Allison E Aiello;Arne N Akbar

  • Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals

    Tapio Nevalainen;Laura Kananen;Saara Marttila;Juulia Jylhävä

  • Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

    Peter K. Joshi;Nicola Pirastu;Katherine A Kentistou;Krista Fischer

  • Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study.

    R. Huttunen;J. Syrjänen;R. Vuento;M. Hurme

  • Gene polymorphisms of interleukins 1 and 10 in infectious and autoimmune diseases

    Mikko Hurme;Nina Lahdenpohja;Sari Santtila

  • The promoter polymorphism of the interleukin-6 gene regulates interleukin-6 production in neonates but not in adults.

    Sanna Kilpinen;Janne Hulkkonen;Xiu-Yun Wang;Mikko Hurme

  • Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis : the Cardiovascular Risk in Young Finns Study

    M. Pertovaara;A. Raitala;M. Juonala;T. Lehtimäki

  • A rare allele combination of the interleukin-1 gene complex is associated with high interleukin-1 beta plasma levels in healthy individuals.

    Hulkkonen J;Laippala P;Hurme M

  • Polymorphisms of the interleukin-1 gene complex in schizophrenia.

    H Katila;K Hänninen;M Hurme

Frequent Co-Authors

Terho Lehtimäki
Terho Lehtimäki Tampere University
Marja Jylhä
Marja Jylhä Tampere University
Olli T. Raitakari
Olli T. Raitakari Turku University Hospital
Mika Kähönen
Mika Kähönen Tampere University
Heini Huhtala
Heini Huhtala Tampere University
Jorma Viikari
Jorma Viikari Turku University Hospital
Mika Kivimäki
Mika Kivimäki University College London
Claudio Franceschi
Claudio Franceschi University of Bologna
Simo S. Oja
Simo S. Oja Tampere University
Antti Vaheri
Antti Vaheri University of Helsinki

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