World's Best Scientists 2026 revealed!
Keiji Naruse

Keiji Naruse

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9880
World Ranking
15689
National Ranking
1116

Overview

Keiji Naruse is affiliated with Okayama University in Japan, focusing on research primarily within Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans several specialized areas, including Molecular Biology, Cardiology and Cardiovascular Medicine, Biomedical Engineering, Surgery, and Physiology.

The scientist's recent publications reflect an interdisciplinary approach, exemplified by works such as In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System (2020, Frontiers in Cell and Developmental Biology), Gravity sensing in plant and animal cells (2021, npj Microgravity), Systematic Understanding of Pathophysiological Mechanisms of Oxidative Stress-Related Conditions-Diabetes Mellitus, Cardiovascular Diseases, and Ischemia-Reperfusion Injury (2021, Frontiers in Cardiovascular Medicine), Treatment of Oxidative Stress with Exosomes in Myocardial Ischemia (2021, International Journal of Molecular Sciences), and The Mechanisms of the Development of Atherosclerosis in Prediabetes (2021, International Journal of Molecular Sciences).

Their research topics include:

  • 3D Printing in Biomedical Research
  • Pluripotent Stem Cells Research
  • Neuroscience and Neural Engineering
  • Tendon Structure and Treatment
  • Spaceflight effects on biology
  • Cardiac Ischemia and Reperfusion
  • Cardiac electrophysiology and arrhythmias

Frequent co-authors collaborating with this researcher are:

  • Ken Takahashi
  • Mengxue Wang
  • Chen Wang
  • Yin Liang
  • Masatoshi Morimatsu

Publications have appeared in several key venues, including:

  • Biophysical Journal
  • Biochemical and Biophysical Research Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Frontiers in Cell and Developmental Biology

Keiji Naruse also has contributions to academic books, notably a publication through Springer Nature titled 11th Asian-Pacific Conference on Medical and Biological Engineering (2021).

Best Publications

  • Mechanical behavior in living cells consistent with the tensegrity model

    Ning Wang;Keiji Naruse;Dimitrije Stamenović;Jeffrey J. Fredberg

  • Subcellular positioning of small molecules.

    Shuichi Takayama;Emanuele Ostuni;Philip LeDuc;Keiji Naruse;Keiji Naruse

  • Involvement of stretch-activated ion channels in Ca2+ mobilization to mechanical stretch in endothelial cells

    K. Naruse;M. Sokabe

  • The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+ Influx and ATP Release in Primary Urothelial Cell Cultures

    Tsutomu Mochizuki;Takaaki Sokabe;Takaaki Sokabe;Isao Araki;Kayoko Fujishita

  • Involvement of SA channels in orienting response of cultured endothelial cells to cyclic stretch

    Keiji Naruse;Takako Yamada;Masahiro Sokabe

  • Selective chemical treatment of cellular microdomains using multiple laminar streams.

    Shuichi Takayama;Emanuele Ostuni;Philip LeDuc;Keiji Naruse

  • Molecular identification of a eukaryotic, stretch-activated nonselective cation channel.

    Makoto Kanzaki;Masahiro Nagasawa;Itaru Kojima;Chikara Sato

  • Calcium regulates the PI3K-Akt pathway in stretched osteoblasts

    Theodora E Danciu;Rosalyn M Adam;Keiji Naruse;Michael R Freeman

  • Fabrication of reconfigurable protein matrices by cracking.

    Xiaoyue Zhu;Kristen L. Mills;Portia R. Peters;Joong Hwan Bahng

  • Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells.

    T. Tetsunaga;K. Nishida;T. Furumatsu;K. Naruse

  • Cyclic strain induces mouse embryonic stem cell differentiation into vascular smooth muscle cells by activating PDGF receptor β

    Nobutaka Shimizu;Kimiko Yamamoto;Syotaro Obi;Shinichiro Kumagaya

  • Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells

    Kiyosumi Shibata;Fumitaka Kikkawa;Akihiro Nawa;Aye Aye Thant

  • Uniaxial Cyclic Stretch Induces Focal Adhesion Kinase (FAK) Tyrosine Phosphorylation Followed by Mitogen-Activated Protein Kinase (MAPK) Activation

    Ju Guang Wang;Motoi Miyazu;Etsushi Matsushita;Masahiro Sokabe

  • The mechanical stimulation of cells in 3D culture within a self-assembling peptide hydrogel

    Yusuke Nagai;Hidenori Yokoi;Keiko Kaihara;Keiji Naruse

  • TRPV2 is critical for the maintenance of cardiac structure and function in mice

    Yuki Katanosaka;Keiichiro Iwasaki;Yoshihiro Ujihara;Satomi Takatsu

  • Aldose reductase inhibition prevents glucose-induced apoptosis in cultured bovine retinal microvascular pericytes.

    K Naruse;J Nakamura;Y Hamada;M Nakayama

  • Pp125FAK is required for stretch dependent morphological response of endothelial cells

    Keiji Naruse;Takako Yamada;Xiao Rui Sai;Michinari Hamaguchi

  • Uni-axial cyclic stretch induces the activation of transcription factor nuclear factor κB in human fibroblast cells

    Hidefumi Inoh;Naoki Ishiguro;Shin Ichi Sawazaki;Hideki Amma

  • Uni-axial cyclic stretch induces c-src activation and translocation in human endothelial cells via SA channel activation.

    Keiji Naruse;Xaurui Sai;Nagao Yokoyama;Masahiro Sokabe

  • Activation of pp60(src) is critical for stretch-induced orienting response in fibroblasts

    Xiaorui Sai;Keiji Naruse;Masahiro Sokabe

Frequent Co-Authors

Masahiro Sokabe
Masahiro Sokabe Nagoya University
Yoshinori Hasegawa
Yoshinori Hasegawa Nagoya University
Shuichi Takayama
Shuichi Takayama Georgia Institute of Technology
Akihiro Kusumi
Akihiro Kusumi Okinawa Institute of Science and Technology
Donald E. Ingber
Donald E. Ingber Harvard University
Yuji Nimura
Yuji Nimura Nagoya University
Naoki Ishiguro
Naoki Ishiguro Nagoya University
Toyoaki Murohara
Toyoaki Murohara Nagoya University
Kaoru Shimokata
Kaoru Shimokata Nagoya University
George M. Whitesides
George M. Whitesides Harvard University

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