World's Best Scientists 2026 revealed!
Nikolaus Osterrieder

Nikolaus Osterrieder

D-Index & Metrics

Microbiology

D-Index
67
Citations
16111
World Ranking
2274
National Ranking
168

Overview

Nikolaus Osterrieder is affiliated with Freie Universität Berlin in Germany and has contributed extensively to the field of infectious diseases, with a particular focus on SARS-CoV-2 and related viral infections. Their research spans multiple facets of medicine and closely intersects with epidemiology, molecular biology, immunology, and animal science and zoology.

The scientist's work is heavily concentrated on viral infections and pathogenesis, often investigating virus-host interactions and disease progression. Key topics covered by their publications include:

  • SARS-CoV-2 and COVID-19 Research
  • Animal Virus Infections Studies
  • Herpesvirus Infections and Treatments
  • COVID-19 Clinical Research Studies
  • Cytomegalovirus and herpesvirus research
  • Viral gastroenteritis research and epidemiology
  • Virus-based gene therapy research

The research output includes a variety of frequent publication venues, suggesting an interdisciplinary approach and active engagement across several scientific journals:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Viruses
  • Journal of Veterinary Internal Medicine
  • SSRN Electronic Journal
  • Transboundary and Emerging Diseases

Osterrieder has been involved in collaborative research with several coauthors, indicating a networked and cooperative research environment. Frequent coauthors include:

  • Jakob Trimpert
  • Achim D. Gruber
  • Dušan Kunec
  • Azza Abdelgawad
  • Daria Vladimirova

Some of the recent papers provide insight into the scientist's research themes and contributions:

  • Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters, 2020, Viruses
  • A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model, 2020, Cell
  • Virus-induced senescence is a driver and therapeutic target in COVID-19, 2021, Nature
  • SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals, 2021, Nature Communications
  • Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry, 2020, Nature Nanotechnology

The combination of topics and venues reveals that the scientist is involved in both fundamental and applied research, especially focusing on viral mechanisms, immune response, and potential therapeutic interventions. Their work also intersects with veterinary medicine, as reflected by publications involving animal models like Syrian hamsters.

The scientific contributions by Nikolaus Osterrieder form part of broader efforts to understand viral diseases, particularly those impacting both human and animal health, with an emphasis on emerging infectious diseases such as COVID-19.

Best Publications

  • Two-step red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli.

    B Karsten Tischer;Jens von Einem;Benedikt Kaufer;Nikolaus Osterrieder

  • En passant mutagenesis: a two step markerless red recombination system.

    B. Karsten Tischer;Gregory A. Smith;Nikolaus Osterrieder;Nikolaus Osterrieder

  • Marek's disease virus: from miasma to model

    Nikolaus Osterrieder;Jeremy P Kamil;Daniel Schumacher;B Karsten Tischer

  • Egress of Alphaherpesviruses: Comparative Ultrastructural Study

    Harald Granzow;Barbara G. Klupp;Walter Fuchs;Jutta Veits

  • Delivery of foreign antigens by engineered outer membrane vesicle vaccines

    David J. Chen;Nikolaus Osterrieder;Nikolaus Osterrieder;Stephan M. Metzger;Elizabeth Buckles

  • The interacting UL31 and UL34 gene products of pseudorabies virus are involved in egress from the host-cell nucleus and represent components of primary enveloped but not mature virions.

    Walter Fuchs;Barbara G. Klupp;Harald Granzow;Nikolaus Osterrieder

  • A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.

    Jakob Kreye;S. Momsen Reincke;Hans Christian Kornau;Hans Christian Kornau;Elisa Sánchez-Sendin;Elisa Sánchez-Sendin;Elisa Sánchez-Sendin

  • Virus-induced senescence is a driver and therapeutic target in COVID-19.

    Soyoung Lee;Soyoung Lee;Yong Yu;Jakob Trimpert;Fahad Benthani

  • Reconstitution of Marek's Disease Virus Serotype 1 (MDV-1) from DNA Cloned as a Bacterial Artificial Chromosome and Characterization of a Glycoprotein B-Negative MDV-1 Mutant

    D Schumacher;B K Tischer;W Fuchs;N Osterrieder

  • SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.

    Nils C. Gassen;Jan Papies;Jan Papies;Thomas Bajaj;Jackson Emanuel;Jackson Emanuel

  • Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters

    Nikolaus Osterrieder;Luca D. Bertzbach;Kristina Dietert;Azza Abdelgawad

  • A point mutation in a herpesvirus polymerase determines neuropathogenicity.

    Laura B Goodman;Arianna Loregian;Gillian A Perkins;Josie Nugent

  • Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

    Jessica J Chiang;Konstantin M J Sparrer;Michiel van Gent;Charlotte Lässig

  • Codon Pair Bias Is a Direct Consequence of Dinucleotide Bias.

    Dusan Kunec;Nikolaus Osterrieder

  • Equine herpesviruses type 1 (EHV-1) and 4 (EHV-4)--masters of co-evolution and a constant threat to equids and beyond.

    Guanggang Ma;Walid Azab;Walid Azab;Nikolaus Osterrieder

  • A virus-encoded telomerase RNA promotes malignant T cell lymphomagenesis.

    Sascha Trapp;Mark S. Parcells;Jeremy P. Kamil;Daniel Schumacher

  • Characterization of Marek's Disease Virus Serotype 1 (MDV-1) Deletion Mutants That Lack UL46 to UL49 Genes: MDV-1 UL49, Encoding VP22, Is Indispensable for Virus Growth

    Fabien Dorange;B. Karsten Tischer;Jean-François Vautherot;Nikolaus Osterrieder

  • Comparison of the efficacy of inactivated combination and modified-live virus vaccines against challenge infection with neuropathogenic equine herpesvirus type 1 (EHV-1).

    Laura B Goodman;Bettina Wagner;M J B F Flaminio;Karen H Sussman

  • Oncogenicity of Virulent Marek's Disease Virus Cloned as Bacterial Artificial Chromosomes

    Lawrence Petherbridge;Andrew C. Brown;Susan J. Baigent;Ken Howes

  • Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation

    Benedikt B. Kaufer;Keith W. Jarosinski;Nikolaus Osterrieder;Nikolaus Osterrieder

  • The protein encoded by the US3 orthologue of Marek's disease virus is required for efficient de-envelopment of perinuclear virions and involved in actin stress fiber breakdown.

    Daniel Schumacher;B. Karsten Tischer;Sascha Trapp;Nikolaus Osterrieder

Frequent Co-Authors

Martin Beer
Martin Beer Friedrich-Loeffler-Institut
Achim D. Gruber
Achim D. Gruber Freie Universität Berlin
Edward J. Dubovi
Edward J. Dubovi Cornell University
Marion L. East
Marion L. East Leibniz Association
Venugopal Nair
Venugopal Nair The Pirbright Institute
Harald Granzow
Harald Granzow Friedrich-Loeffler-Institut
Douglas F. Antczak
Douglas F. Antczak Cornell University
Ralf Wagner
Ralf Wagner University of Regensburg
Marcel A. Müller
Marcel A. Müller Charité - University Medicine Berlin
Dietmar Schmitz
Dietmar Schmitz Charité - University Medicine Berlin

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