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Microbiology

D-Index
49
Citations
9682
World Ranking
4550
National Ranking
402

Overview

Venugopal Nair is affiliated with The Pirbright Institute in the United Kingdom. Their research spans multiple fields, primarily Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader domains, they have contributed notably to subfields such as Epidemiology, Molecular Biology, Genetics, Immunology, and Animal Science and Zoology.

The scientist's work covers a variety of topics, including:

  • Herpesvirus Infections and Treatments
  • Cytomegalovirus and herpesvirus research
  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering
  • Animal Virus Infections Studies
  • Interferon and immune responses
  • Viral Infections and Immunology Research

Venugopal Nair has coauthored research frequently with a group of collaborators noted for sustained partnerships. These include Yongxiu Yao, Man Teng, Jun Luo, Yaoyao Zhang, and Gaiping Zhang.

Their publications have appeared in a range of journals with particular frequency in Viruses, Journal of Virology, PLoS Pathogens, Vaccines, and Poultry Science. Among the key papers authored or coauthored by them are:

  • "Latest Advances of Virology Research Using CRISPR/Cas9-Based Gene-Editing Technology and Its Application to Vaccine Development" (2021), Viruses
  • "Generation of A Triple Insert Live Avian Herpesvirus Vectored Vaccine Using CRISPR/Cas9-Based Gene Editing" (2020), Vaccines
  • "Acquiring Resistance Against a Retroviral Infection via CRISPR/Cas9 Targeted Genome Editing in a Commercial Chicken Line" (2020), Frontiers in Genome Editing
  • "ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells" (2020), PLoS Pathogens
  • "Dissection of key factors correlating with H5N1 avian influenza virus driven inflammatory lung injury of chicken identified by single-cell analysis" (2023), PLoS Pathogens

Their research demonstrates a focus on the application of CRISPR/Cas9 gene-editing technologies for virology and vaccine development, as well as investigations into immune response mechanisms and viral pathogenesis in animal models. The use of cutting-edge genetic engineering approaches is a significant aspect of their work, particularly in relation to herpesviruses and avian viruses.

This body of work places Venugopal Nair at the intersection of molecular biology and epidemiology, contributing to understanding disease mechanisms and developing advanced preventative strategies in animal health and virology.

Best Publications

  • Imperfect vaccination can enhance the transmission of highly virulent pathogens

    Andrew F. Read;Susan J. Baigent;Claire Powers;Lydia B. Kgosana

  • The long view: 40 years of avian leukosis research

    L N Payne;V Nair

  • Evolution of Marek's disease--a paradigm for incessant race between the pathogen and the host

    Venugopal Nair

  • A robust system for RNA interference in the chicken using a modified microRNA operon

    Raman M Das;Nick J Van Hateren;Gareth R Howell;Elizabeth R Farrell

  • Critical Role of the Virus-Encoded MicroRNA-155 Ortholog in the Induction of Marek's Disease Lymphomas

    Yuguang Zhao;Hongtao Xu;Yongxiu Yao;Lorraine P. Smith

  • Absolute quantitation of Marek's disease virus genome copy number in chicken feather and lymphocyte samples using real-time PCR.

    Susan J. Baigent;Lawrence J. Petherbridge;Ken Howes;Lorraine P. Smith

  • A Functional MicroRNA-155 Ortholog Encoded by the Oncogenic Marek's Disease Virus

    Yuguang Zhao;Yongxiu Yao;Hongtao Xu;Luke Lambeth

  • Global distributions and strain diversity of avian infectious bronchitis virus: a review.

    Faruku Bande;Siti Suri Arshad;Abdul Rahman Omar;Mohd Hair-Bejo

  • Interaction of MEQ protein and C-terminal-binding protein is critical for induction of lymphomas by Marek's disease virus

    Andrew C. Brown;Susan J. Baigent;Lorraine P. Smith;Jason P. Chattoo

  • MicroRNA Profile of Marek's Disease Virus-Transformed T-Cell Line MSB-1: Predominance of Virus-Encoded MicroRNAs

    Yongxiu Yao;Yuguang Zhao;Hongtao Xu;Lorraine P. Smith

  • Virus-encoded microRNAs: novel regulators of gene expression.

    Venugopal Nair;Mihaela Zavolan

  • A virus-encoded telomerase RNA promotes malignant T cell lymphomagenesis.

    Sascha Trapp;Mark S. Parcells;Jeremy P. Kamil;Daniel Schumacher

  • Oncogenicity of Virulent Marek's Disease Virus Cloned as Bacterial Artificial Chromosomes

    Lawrence Petherbridge;Andrew C. Brown;Susan J. Baigent;Ken Howes

  • Use of Marek's disease vaccines: could they be driving the virus to increasing virulence?

    Fred Davison;Venugopal Nair

  • Horizontal transmission of Marek's disease virus requires US2, the UL13 protein kinase, and gC.

    Keith W. Jarosinski;Neil G. Margulis;Jeremy P. Kamil;Stephen J. Spatz

  • Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

    Paul E Chappell;El Kahina Meziane;Michael Harrison;Łukasz Magiera

  • Attenuation of Marek's Disease Virus by Deletion of Open Reading Frame RLORF4 but Not RLORF5a

    Keith W. Jarosinski;Nikolaus Osterrieder;Venugopal K. Nair;Karel A. Schat

  • Infection of macrophages by a lymphotropic herpesvirus: a new tropism for Marek's disease virus.

    Alexander D. Barrow;Shane C. Burgess;Susan J. Baigent;Ken Howes

  • Vaccinal control of Marek's disease: Current challenges, and future strategies to maximize protection

    Susan J. Baigent;Lorraine P. Smith;Venugopal K. Nair;Richard J.W. Currie

  • Replication-Competent Bacterial Artificial Chromosomes of Marek's Disease Virus: Novel Tools for Generation of Molecularly Defined Herpesvirus Vaccines

    Lawrence Petherbridge;Ken Howes;Susan J. Baigent;Melanie A. Sacco

  • Genomes & Developmental Control A robust system for RNA interference in the chicken using a modified microRNA operon

    Raman M. Das;Nick J. Van Hateren;Gareth R. Howell;Elizabeth R. Farrell

Frequent Co-Authors

Nikolaus Osterrieder
Nikolaus Osterrieder Freie Universität Berlin
Jae Yong Han
Jae Yong Han Seoul National University
Andrew F. Read
Andrew F. Read Pennsylvania State University
Peter K. Kaiser
Peter K. Kaiser Cleveland Clinic
Martin J. Allday
Martin J. Allday Imperial College London
James C. Kaufman
James C. Kaufman University of Connecticut
Adrian Smith
Adrian Smith University of Oxford
Michael A. Skinner
Michael A. Skinner Imperial College London
Mihaela Zavolan
Mihaela Zavolan University of Basel
Xiufan Liu
Xiufan Liu Yangzhou University

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