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Biology and Biochemistry

D-Index
55
Citations
11311
World Ranking
15024
National Ranking
6286

Overview

Michael C. Mahaney is affiliated with The University of Texas Rio Grande Valley in the United States. Their research spans a multidisciplinary approach within the fields of biochemistry, genetics, molecular biology, and medicine. A significant body of their work contributes to understanding genetic associations, epidemiology, and molecular mechanisms relevant to diseases and physiological processes.

The scientist has published extensively in various subfields including genetics, molecular biology, cardiology and cardiovascular medicine, physiology, and immunology. Research topics frequently covered in their publications include genetic associations and epidemiology, gut microbiota and health, genomic variations and chromosomal abnormalities, diet and metabolism studies, cancer-related molecular mechanisms, atherosclerosis and cardiovascular diseases, and salivary gland disorders and functions.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer's & Dementia
  • Circulation Genomic and Precision Medicine
  • Frontiers in Genetics
  • Nature Genetics

Their recent influential papers include:

  • "Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale" (2020, Nature Genetics)
  • "Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study" (2023, Scientific Reports)
  • "Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification" (2023, Nature Cardiovascular Research)
  • "Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study" (2023, The American Journal of Human Genetics)
  • "Keeping 21st Century Paleontology Grounded: Quantitative Genetic Analyses and Ancestral State Reconstruction Re-Emphasize the Essentiality of Fossils" (2022, Biology)

Collaborations play a key role in their research, with frequent co-authors including:

  • John Blangero
  • Joanne E. Curran
  • May E. Montasser
  • Joshua C. Bis
  • Barry I. Freedman

Best Publications

  • Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes.

    Harald H H Göring;Joanne E Curran;Matthew P Johnson;Thomas D Dyer

  • A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

    Anthony G. Comuzzie;James E. Hixson;Laura Almasy;Braxton D. Mitchell

  • Genetic variation in selenoprotein S influences inflammatory response.

    Joanne E Curran;Jeremy B M Jowett;Kate S Elliott;Yuan Gao

  • Genetic Contribution of the Endothelial Constitutive Nitric Oxide Synthase Gene to Plasma Nitric Oxide Levels

    Xing L. Wang;Michael C. Mahaney;Ah Siew. Sim;Jun Wang

  • Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans: The San Antonio Family Heart Study

    Braxton D. Mitchell;Candace M. Kammerer;John Blangero;Michael C. Mahaney

  • Plasma lipid profiling in a large population-based cohort

    Jacquelyn M. Weir;Gerard Wong;Christopher K. Barlow;Melissa A. Greeve

  • Chemerin Is Associated with Metabolic Syndrome Phenotypes in a Mexican-American Population

    Kiymet Bozaoglu;David Segal;Katherine A. Shields;Nick Cummings

  • Genetic Analysis of the IRS Pleiotropic Effects of Genes Influencing Insulin Levels on Lipoprotein and Obesity Measures

    Braxton D. Mitchell;Candace M. Kammerer;Michael C. Mahaney;John Blangero

  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

    Xihao Li;Zilin Li;Hufeng Zhou;Sheila M Gaynor

  • A genetic linkage map of the baboon (Papio hamadryas) genome based on human microsatellite polymorphisms.

    Jeffrey Rogers;Michael C. Mahaney;Shelly M. Witte;Shalini Nair

  • Normal Variation in Leptin Levels Is Associated with Polymorphisms in the Proopiomelanocortin Gene, POMC*

    James E. Hixson;Laura Almasy;Shelley Cole;Shifra Birnbaum

  • The baboon as a nonhuman primate model for the study of the genetics of obesity

    Anthony G. Comuzzie;Shelley A. Cole;Lisa Martin;K. Dee Carey

  • Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases

    Hong Wen Deng;Hong Wen Deng;Michael C. Mahaney;Jeff T. Williams;Jing Li

  • Novel epigenetic determinants of type 2 diabetes in mexican american families

    Hemant Kulkarni;Mark Z. Kos;Jennifer Neary;Thomas D. Dyer

  • Major gene with sex-specific effects influences fat mass in Mexican Americans

    Anthony G. Comuzzie;John Blangero;Michael C. Mahaney;Braxton D. Mitchell

  • Effects of Genes, Sex, Age, and Activity on BMC, Bone Size, and Areal and Volumetric BMD

    Lorena M Havill;Michael C Mahaney;Teresa L Binkley;Bonny L Specker

  • Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes.

    Jac C. Charlesworth;Jac C. Charlesworth;Joanne E. Curran;Matthew P. Johnson;Harald H H Göring

  • Baboons as a Model to Study Genetics and Epigenetics of Human Disease

    Laura A. Cox;Anthony G. Comuzzie;Lorena M. Havill;Genesio M. Karere

  • Genetic Contributions to Plasma Total Antioxidant Activity

    Xing Li Wang;David L. Rainwater;Jane F. VandeBerg;Braxton D. Mitchell

  • Plasma HDL Cholesterol, Triglycerides, and Adiposity A Quantitative Genetic Test of the Conjoint Trait Hypothesis in the San Antonio Family Heart Study

    Michael C. Mahaney;John Blangero;Anthony G. Comuzzie;John L. VandeBerg

Frequent Co-Authors

John Blangero
John Blangero The University of Texas Rio Grande Valley
Anthony G. Comuzzie
Anthony G. Comuzzie Obesity Society
John L. VandeBerg
John L. VandeBerg The University of Texas Rio Grande Valley
Thomas D. Dyer
Thomas D. Dyer The University of Texas Rio Grande Valley
Laura Almasy
Laura Almasy University of Pennsylvania
Shelley A. Cole
Shelley A. Cole Texas Biomedical Research Institute
Harald H H Göring
Harald H H Göring The University of Texas at Austin
Jeffrey Rogers
Jeffrey Rogers Baylor College of Medicine
Eric K. Moses
Eric K. Moses University of Western Australia
Michael P. Stern
Michael P. Stern The University of Texas Health Science Center at San Antonio

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