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Immunology

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76
Citations
23172
World Ranking
1896
National Ranking
922

Medicine

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76
Citations
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World Ranking
18725
National Ranking
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Overview

Brian L. Kotzin is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research primarily focuses on fields related to Medicine and Immunology and Microbiology, with a notable emphasis on Immunology, Radiology, Nuclear Medicine and Imaging, Oncology, Dermatology, and Immunology and Allergy.

Their work covers main topics including Immune Cell Function and Interaction, T-cell and B-cell Immunology, Monoclonal and Polyclonal Antibodies Research, Dermatology and Skin Diseases, Allergic Rhinitis and Sensitization, Systemic Lupus Erythematosus Research, and Cytokine Signaling Pathways and Interactions.

Brian L. Kotzin has contributed to several recent research papers, including:

  • Selective expansion of regulatory T cells by NKTR-358 in healthy volunteers and patients with systemic lupus erythematosus, 2022, Journal of Translational Autoimmunity
  • The regulatory T cell-selective interleukin-2 receptor agonist rezpegaldesleukin in the treatment of inflammatory skin diseases: two randomized, double-blind, placebo-controlled phase 1b trials, 2024, Nature Communications
  • THU0054 NKTR-358, A NOVEL IL-2 CONJUGATE, STIMULATES HIGH LEVELS OF REGULATORY T CELLS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, 2020, Annals of the Rheumatic Diseases
  • 1026TiP A phase Ib/II, open-label, multicenter, dose-escalation and dose-expansion study of NKTR-255 plus cetuximab as a salvage regimen in patients with solid tumors, 2021, Annals of Oncology
  • REZPEGALDESLEUKIN, NOVEL TREG-INDUCING THERAPY, DEMONSTRATES EFFICACY IN ATOPIC DERMATITIS AND ASTHMA IN PHASE 2B TRIAL, 2025, Annals of Allergy Asthma & Immunology

Frequent co-authors include:

  • Jonathan Zalevsky
  • Christie Fanton
  • Mary Tagliaferri
  • Jonathan I. Silverberg
  • David Rosmarin

Brian L. Kotzin's publications appear in journals such as:

  • Nature Communications
  • Journal of Translational Autoimmunity
  • Annals of the Rheumatic Diseases
  • Annals of Oncology
  • Annals of Allergy Asthma & Immunology

Best Publications

  • Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

    Yongwon Choi;Brian Kotzin;Lynne Herron;Jill Callahan

  • Vβ-specific stimulation of human T cells by staphylococcal toxins

    John Kappler;Brian Kotzin;Lynne Herron;Erwin W. Gelfand

  • Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis

    Mark Lebwohl;Bruce Strober;Alan Menter;Kenneth Gordon

  • Superantigens and their potential role in human disease.

    Brian L. Kotzin;Donald Y.M. Leung;John Kappler;John Kappler;Philippa Marrack;Philippa Marrack

  • Evidence for the effects of a superantigen in rheumatoid arthritis

    Xavier Paliard;Sterling G. West;Joyce A. Lafferty;Janice R. Clements

  • Autoimmune disease: why and where it occurs

    Philippa Marrack;John Kappler;Brian L. Kotzin

  • Systemic Lupus Erythematosus

    Unknown

  • Immunologic Responses Associated with 12 Weeks of Combination Antiretroviral Therapy Consisting of Zidovudine, Lamivudine, and Ritonavir: Results of AIDS Clinical Trials Group Protocol 315

    Michael Marcel Lederman;Elizabeth Connick;Alan Landay;Daniel R. Kuritzkes

  • Selective expansion of T cells expressing T-cell receptor variable regions V beta 2 and V beta 8 in Kawasaki disease.

    Jun Abe;Brian L. Kotzin;Kazuhito Jujo;Marian E. Melish

  • Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes.

    W P LeFeber;D A Norris;S R Ryan;J C Huff

  • Weekly Pulse Methotrexate in Rheumatoid Arthritis: Clinical and Immunologic Effects in a Randomized, Double-Blind Study

    Peter A. Andersen;Sterling G. West;James R. O'dell;Charles S. Via

  • Selective expansion of T cells expressing V beta 2 in toxic shock syndrome.

    Y Choi;J A Lafferty;J R Clements;J K Todd

  • Evidence for an Interferon-Inducible Gene, Ifi202, in the Susceptibility to Systemic Lupus

    Stephen J Rozzo;John D Allard;Divaker Choubey;Timothy J Vyse

  • Association of psychiatric manifestations with antibodies to ribosomal P proteins in systemic lupus erythematosus.

    Andrea B. Schneebaum;James D. Singleton;Sterling G. West;James K. Blodgett

  • Neuropsychiatric lupus erythematosus: A 10-year prospective study on the value of diagnostic tests

    Sterling G. West;Woodruff Emlen;Mark H. Wener;Brian L. Kotzin

  • Preferential T-cell receptor beta-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis.

    Brian L. Kotzin;Satyanarayana Karuturi;Yuan K. Chou;Joyce Lafferty

  • Treatment of intractable rheumatoid arthritis with total lymphoid irradiation.

    Brian L. Kotzin;Samuel Strober;Edgar G. Engleman;Andrei Calin

  • Characterization of T Cell Repertoire Changes in Acute Kawasaki Disease.

    J. Abe;B. L. Kotzin;C. Meissner;M. E. Melish

  • Immune Reconstitution in the First Year of Potent Antiretroviral Therapy and Its Relationship to Virologic Response

    Elizabeth Connick;Michael Marcel Lederman;Brian L. Kotzin;John Spritzler

  • Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis.

    J E Fitzgerald;N S Ricalton;A C Meyer;S G West

  • Analysis of cognitive and psychological deficits in systemic lupus erythematosus patients without overt central nervous system disease

    Elizabeth Kozora;Laetitia L. Thompson;Sterling G. West;Brian L. Kotzin

  • Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice

    Charles G. Drake;Susan K. Babcock;E. D. Palmer;Brian L. Kotzin

Frequent Co-Authors

Shozo Izui
Shozo Izui University of Geneva
Andrew P. Fontenot
Andrew P. Fontenot University of Colorado Anschutz Medical Campus
Lee S. Newman
Lee S. Newman University of Colorado Anschutz Medical Campus
Timothy J. Vyse
Timothy J. Vyse King's College London
Philippa Marrack
Philippa Marrack National Jewish Health
John W. Kappler
John W. Kappler National Jewish Health
Donald Y.M. Leung
Donald Y.M. Leung National Jewish Health
Ed Palmer
Ed Palmer University of Basel
Divaker Choubey
Divaker Choubey University of Cincinnati
Laurence Morel
Laurence Morel The University of Texas Health Science Center at San Antonio

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