Ed Palmer

Best Publications

• Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

  Mark A. Daniels;Emma Teixeiro;Jason Gill;Barbara Hausmann

  712
  Citations

• Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question.

  Elliot J. Suchin;Peter B. Langmuir;Ed Palmer;Mohamed H. Sayegh

  663
  Citations

• Negative selection — clearing out the bad apples from the T-cell repertoire

  Unknown

  493
  Citations

• Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)

  Saulius Zuklys;Gina Balciunaite;Gina Balciunaite;Anni Agarwal;Anni Agarwal;Elizaveta Fasler-Kan

  377
  Citations

• An endogenous retrovirus mediating deletion of alpha beta T cells

  David L. Woodland;Mary Pat Happ;Kenneth J. Gollob;Ed Palmer;Ed Palmer

  369
  Citations

• The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model.

  Caridad Rosette;Guy Werlen;Mark A Daniels;Philmore O Holman

  307
  Citations

• A motif in the αβ T-cell receptor controls positive selection by modulating ERK activity

  Unknown

  305
  Citations

• Requirement for cotolerogenic gene products in the clonal deletion of I-E reactive T cells.

  David Woodland;Mary Pat Happ;Jerome Bill;Ed Palmer

  251
  Citations

• Signaling Life and Death in the Thymus: Timing Is Everything

  Unknown

  250
  Citations

• Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides

  Andrew J Leishman;Laurent Gapin;Myriam Capone;Ed Palmer

  249
  Citations

• Essential role of CD8 palmitoylation in CD8 coreceptor function.

  Alexandre Arcaro;Claude Grégoire;Nicole Boucheron;Sabine Stotz

  244
  Citations

• Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice

  Charles G. Drake;Susan K. Babcock;E. D. Palmer;Brian L. Kotzin

  240
  Citations

• Different T cell receptor signals determine CD8+ memory versus effector development.

  Emma Teixeiro;Emma Teixeiro;Mark A. Daniels;Mark A. Daniels;Sara E. Hamilton;Adam G. Schrum;Adam G. Schrum

  235
  Citations

• Mls — a retrovirus exploits the immune system

  Unknown

  233
  Citations

• T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

  Carolyn G. King;Sabrina Koehli;Barbara Hausmann;Mathias Schmaler

  227
  Citations

• A role for clonal inactivation in T cell tolerance to Mls-1a.

  Marcia A. Blackman;Hans Gerhard-Burgert;David L. Woodland;Ed Palmer

  223
  Citations

• Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner.

  C G Drake;S J Rozzo;H F Hirschfeld;N P Smarnworawong

  204
  Citations

• Coreceptor Scanning by the T Cell Receptor Provides a Mechanism for T Cell Tolerance

  Ondrej Stepanek;Arvind S. Prabhakar;Celine Osswald;Carolyn G. King

  184
  Citations

• T cell receptor engagement by peptide–MHC ligands induces a conformational change in the CD3 complex of thymocytes

  Diana Gil;Adam G. Schrum;Balbino Alarcón;Ed Palmer

  161
  Citations

• Positive Selection Through a Motif in the αβ T Cell Receptor

  Unknown

  161
  Citations