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Immunology

D-Index
66
Citations
20319
World Ranking
2728
National Ranking
1299

Research.com Recognitions

  • 2009 - National Institutes of Health Director's Pioneer Award

Overview

Hilde Cheroutre is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research primarily focuses on immunology and microbiology, with a significant concentration on immune cell function and interaction as well as T-cell and B-cell immunology.

The scientist's work addresses various aspects of immunotherapy and immune responses, including studies related to IL-33, ST2, and ILC pathways. Other areas of interest include CAR-T cell therapy research, single-cell and spatial transcriptomics, and immune response and inflammation.

Key recent publications by Hilde Cheroutre include the following:

  • Transcriptomes and metabolism define mouse and human MAIT cell populations, 2023, Science Immunology
  • Epithelial HVEM maintains intraepithelial T cell survival and contributes to host protection, 2022, Science Immunology
  • HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160, 2021, The Journal of Experimental Medicine
  • A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function, 2023, Immunity
  • Intra-tumoral T cells in pediatric brain tumors display clonal expansion and effector properties, 2024, Nature Cancer

Frequent coauthors collaborating with Cheroutre include Mitchell Kronenberg, Greet Verstichel, Goo-Young Seo, Ting-Fang Chou, and Kiyokazu Kakugawa.

They have published predominantly in The Journal of Immunology, bioRxiv (Cold Spring Harbor Laboratory), Science Immunology, Immunity, and The Journal of Experimental Medicine.

Hilde Cheroutre was awarded the National Institutes of Health Director's Pioneer Award in 2009.

Best Publications

  • IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

    Sergei Grivennikov;Eliad Karin;Janos Terzic;Janos Terzic;Daniel Mucida

  • Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.

    Daniel Mucida;Yunji Park;Gisen Kim;Olga Turovskaya

  • Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.

    Sergei I. Grivennikov;Kepeng Wang;Daniel Mucida;C. Andrew Stewart

  • Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

    Masako Murai;Olga Turovskaya;Gisen Kim;Rajat Madan

  • The light and dark sides of intestinal intraepithelial lymphocytes

    Hilde Cheroutre;Florence Lambolez;Daniel Mucida

  • Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis.

    Diana M. Shih;Yu-Rong Xia;Xu-Ping Wang;Elizabeth Miller

  • Overexpression of Interleukin-10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor–Deficient Mice by Altering Lymphocyte and Macrophage Phenotypes

    Laura J. Pinderski;Michael P. Fischbein;Ganesamoorthy Subbanagounder;Michael C. Fishbein

  • Molecular cloning of human interleukin 2 cDNA and its expression in E. coli

    Rene Devos;Geert Plaetinck;Hilde Cheroutre;Guus Simons

  • Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

    Daniel Mucida;Mohammad Mushtaq Husain;Sawako Muroi;Femke Van Wijk

  • Altered immune responses in interleukin 10 transgenic mice.

    Amy Hagenbaugh;Sherven Sharma;Steven M. Dubinett;Sherry H.-Y. Wei

  • T Cell Responses Modulated Through Interaction Between CD8αα and the Nonclassical MHC Class I Molecule, TL

    Andrew J. Leishman;Olga V. Naidenko;Antoine Attinger;Frits Koning;Frits Koning

  • Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes

    Ricard Garcia-Carbonell;Ajit S. Divakaruni;Alessia Lodi;Ildefonso Vicente-Suarez

  • Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction.

    Raziya B. Shaikh;Sybil Santee;Steven W. Granger;Kristine Butrovich

  • Starting at the Beginning: New Perspectives on the Biology of Mucosal T Cells

    Hilde Cheroutre

  • Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells

    Rene Devos;Hilde Cheroutre;Yoichi Taya;Wim Degrave

  • Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.

    Maya F. Kotturi;Iain Scott;Tom Wolfe;Bjoern Peters

  • Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides

    Andrew J Leishman;Laurent Gapin;Myriam Capone;Ed Palmer

  • Retinoic Acid and Retinoic Acid Receptors as Pleiotropic Modulators of the Immune System.

    Alexandre Larange;Hilde Cheroutre

  • CD8αα-Mediated Survival and Differentiation of CD8 Memory T Cell Precursors

    Loui T. Madakamutil;Urs Christen;Christopher J. Lena;Yiran Wang-Zhu

  • Retinoic Acid Can Directly Promote TGF-β-Mediated Foxp3+ Treg Cell Conversion of Naive T Cells

    Daniel Mucida;Karina Pino-Lagos;Gisen Kim;Elizabeth Nowak

Frequent Co-Authors

Mitchell Kronenberg
Mitchell Kronenberg University of California, San Diego
Daniel Mucida
Daniel Mucida Rockefeller University
Walter Fiers
Walter Fiers Ghent University
Carl F. Ware
Carl F. Ware Sanford Burnham Prebys Medical Discovery Institute
Stephen P. Schoenberger
Stephen P. Schoenberger La Jolla Institute For Allergy & Immunology
Yoichi Taya
Yoichi Taya National University of Singapore
Lars Eckmann
Lars Eckmann University of California, San Diego
Michael Karin
Michael Karin University of California, San Diego
Michael A. Teitell
Michael A. Teitell University of California, Los Angeles
Leroy Hood
Leroy Hood University of Washington

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