Philippe P. Roux

Overview

Best Publications

• Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

  Marie Cargnello;Philippe P. Roux

  3462
  Citations

• ERK AND P38 MAPK-ACTIVATED PROTEIN KINASES: A FAMILY OF PROTEIN KINASES WITH DIVERSE BIOLOGICAL FUNCTIONS

  Philippe P. Roux;John Blenis

  3183
  Citations

• Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.

  Andrew R Tee;Brendan D Manning;Brendan D Manning;Philippe P Roux;Lewis C Cantley;Lewis C Cantley

  1479
  Citations

• Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

  Philippe P. Roux;Bryan A. Ballif;Rana Anjum;Steven P. Gygi

  957
  Citations

• Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

  Andrew Y. Choo;Sang-Oh Yoon;Sang Gyun Kim;Philippe P. Roux

  957
  Citations

• Neurotrophin signaling through the p75 neurotrophin receptor.

  Philippe P Roux;Philip A Barker

  932
  Citations

• RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation

  Philippe P. Roux;David Shahbazian;Hieu Vu;Marina K. Holz

  838
  Citations

• The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

  David Shahbazian;Philippe P Roux;Virginie Mieulet;Michael S Cohen

  648
  Citations

• mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

  Louis-Andre Julien;Audrey Carriere;Julie Moreau;Philippe P. Roux

  520
  Citations

• Regulation and function of the RSK family of protein kinases.

  Yves Romeo;Xiaocui Zhang;Philippe P. Roux

  413
  Citations

• Actin cortex architecture regulates cell surface tension

  Priyamvada Chugh;Andrew G. Clark;Andrew G. Clark;Matthew B. Smith;Davide A. D. Cassani

  412
  Citations

• Oncogenic MAPK Signaling Stimulates mTORC1 Activity by Promoting RSK-Mediated Raptor Phosphorylation

  Audrey Carrière;Marie Cargnello;Louis-André Julien;Huanhuan Gao

  404
  Citations

• NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis.

  Amir H Salehi;Philippe P Roux;Chris J Kubu;Christine Zeindler

  391
  Citations

• mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

  Won Jun Oh;Chang chih Wu;Sung Jin Kim;Valeria Facchinetti

  363
  Citations

• Signaling Pathways Involved in the Regulation of mRNA Translation.

  Philippe P Roux;Ivan Topisirovic

  326
  Citations

• ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)

  Audrey Carriere;Yves Romeo;Hugo A. Acosta-Jaquez;Julie Moreau

  306
  Citations

• A comprehensive map of the mTOR signaling network.

  Etienne Caron;Samik Ghosh;Yukiko Matsuoka;Dariel Ashton‐Beaucage

  293
  Citations

• p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure.

  Philippe P. Roux;Michael A. Colicos;Philip A. Barker;Timothy E. Kennedy

  285
  Citations

• Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation

  Joseph Tcherkezian;Perry A. Brittis;Franziska Thomas;Philippe P. Roux

  285
  Citations

• Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′TOP mRNA translation

  Joseph Tcherkezian;Marie Cargnello;Yves Romeo;Yves Romeo;Edward L. Huttlin

  280
  Citations