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Robert Layfield

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
38643
World Ranking
17379
National Ranking
1364

Robert Layfield publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Robert Layfield sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 194 publications — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Robert Layfield D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Robert Layfield sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 50 D-Index — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Robert Layfield is affiliated with the University of Nottingham in the United Kingdom. Their research spans across the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine, with specific subfields including Molecular Biology, Genetics, Organic Chemistry, Neurology, and Oncology.

Their recent publication record highlights contributions to chemical modifications of peptides and proteins, neurobiology, and cellular signaling pathways. Notable papers include:

  • Site-Selective Modification of Peptides and Proteins via Interception of Free-Radical-Mediated Dechalcogenation, 2020, Angewandte Chemie International Edition
  • Site-Selective Installation of Nϵ-Modified Sidechains into Peptide and Protein Scaffolds via Visible-Light-Mediated Desulfurative C-C Bond Formation, 2021, Angewandte Chemie International Edition
  • p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death, 2021, Scientific Reports
  • ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation, 2020, Molecular and Cellular Neuroscience
  • Cysteine-Selective Modification of Peptides and Proteins via Desulfurative C−C Bond Formation, 2022, Chemistry - A European Journal

Their work has been published repeatedly in venues such as Neuro-Oncology, IUPHAR/BPS Guide to Pharmacology CITE, Angewandte Chemie International Edition, Scientific Reports, and Angewandte Chemie.

Frequent collaborators within their research network include:

  • Farhana Haque
  • Ruman Rahman
  • Elena Faccenda
  • Anya Snary
  • Jed Long

Layfield's research topics cover a range of biochemical and pharmacological areas, including:

  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors
  • Click Chemistry and Applications
  • Glioma Diagnosis and Treatment
  • Chemical Synthesis and Analysis
  • Peptidase Inhibition and Analysis
  • Autophagy in Disease and Therapy

In addition to articles, Layfield has contributed to book publications, including titles published by IntechOpen. One such work is Modifications in Biomacromolecules from 2022.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle.

    Paul L. Greenhaff;Leonidas Karagounis;Nicholas Peirce;Elizabeth J Simpson

  • α-Synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

    George K Tofaris;Robert Layfield;Maria Grazia Spillantini

  • Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies

    Lynn Bedford;David Hay;Anny Devoy;Simon Paine

  • Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

    Y A Lam;C M Pickart;A Alban;M Landon

  • Proteasomal degradation of tau protein.

    Della C. David;Robert Layfield;Louise Serpell;Yolanda Narain

  • Oligodendrocytes Promote Neuronal Survival and Axonal Length by Distinct Intracellular Mechanisms: A Novel Role for Oligodendrocyte-Derived Glial Cell Line-Derived Neurotrophic Factor

    Alastair Wilkins;Henry Majed;Robert Layfield;Alastair Compston

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway

    Ian M. Copple;Adam Lister;Akua D. Obeng;Neil R. Kitteringham

  • Neurofibrillary tangles of Alzheimer's disease brains contain 14-3-3 proteins.

    Layfield R;Fergusson J;Aitken A;Lowe J

  • Ubiquitin recognition by the ubiquitin-associated domain of p62 involves a novel conformational switch.

    Jed Long;Thomas R.A. Gallagher;James R. Cavey;Paul W. Sheppard

  • Pathogenesis of Paget Disease of Bone

    Stuart H. Ralston;Rob Layfield

  • Boning up on autophagy: the role of autophagy in skeletal biology.

    Irving M Shapiro;Robert Layfield;Martin Lotz;Carmine Settembre

  • Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences.

    Lynne J. Hocking;Gavin J. A. Lucas;Anna Daroszewska;Tim Cundy

  • SQSTM1 mutations--bridging Paget disease of bone and ALS/FTLD

    Sarah L. Rea;Veronika Majcher;Mark S. Searle;Rob Layfield

  • Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders.

    Robert Layfield;James R Cavey;James Lowe

  • Oligodendrocytes promote neuronal survival and axonal length by distinct intracellular mechanisms

    Alastair Wilkins;Henry Majed;Robert Layfield;Alastair Compston

Frequent Co-Authors

Mark S. Searle
Mark S. Searle University of Nottingham
Stuart H. Ralston
Stuart H. Ralston University of Edinburgh
Neil J. Oldham
Neil J. Oldham University of Nottingham
Sergio Lavandero
Sergio Lavandero University of Chile
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Evelina Gatti
Evelina Gatti Aix-Marseille University
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Felix Randow
Felix Randow MRC Laboratory of Molecular Biology
Philippe Pierre
Philippe Pierre Aix-Marseille University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

External Links

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Best Scientists Citing Robert Layfield

Daniel J. Klionsky

Daniel J. Klionsky

University of Michigan–Ann Arbor

Publications: 57

Guido Kroemer

Guido Kroemer

Université Paris Cité

Publications: 49

Stuart M. Phillips

Stuart M. Phillips

McMaster University

Publications: 48

Stuart H. Ralston

Stuart H. Ralston

University of Edinburgh

Publications: 45

Masaaki Komatsu

Masaaki Komatsu

Juntendo University

Publications: 43

Kenneth Smith

Kenneth Smith

University of Nottingham

Publications: 43

Saeid Ghavami

Saeid Ghavami

University of Manitoba

Publications: 37

Paul L. Greenhaff

Paul L. Greenhaff

University of Nottingham

Publications: 36

David C. Rubinsztein

David C. Rubinsztein

University of Cambridge

Publications: 35

Sergio Lavandero

Sergio Lavandero

University of Chile

Publications: 35

Gábor Juhász

Gábor Juhász

Eötvös Loránd University

Publications: 32

Anne Simonsen

Anne Simonsen

University of Oslo

Publications: 31

Ana Maria Cuervo

Ana Maria Cuervo

Albert Einstein College of Medicine

Publications: 31

Terje Johansen

Terje Johansen

University of Tromsø - The Arctic University of Norway

Publications: 30

Patrice Codogno

Patrice Codogno

Université Paris Cité

Publications: 30

Ciro Isidoro

Ciro Isidoro

University of Eastern Piedmont Amadeo Avogadro

Publications: 29

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