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Genetics

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Molecular Biology

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Research.com Recognitions

  • 1998 - Fellow of American Physical Society (APS) Citation For fundamental studies of the biochemistry of nucleic acids with particular regard to recombinantDNA
  • 1988 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1987 - Fellow of the Royal Society, United Kingdom
  • 1980 - Nobel Prize for their contributions concerning the determination of base sequences in nucleic acids
  • 1979 - Canada Gairdner International Award
  • 1979 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 1979 - Louisa Gross Horwitz Prize, Columbia University
  • 1976 - Member of the National Academy of Sciences
  • 1968 - Fellow of the American Academy of Arts and Sciences
  • 1967 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1947 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Walter Gilbert is affiliated with Harvard University in the United States. Their research spans important areas of medicine and biochemistry, genetics, and molecular biology. Specifically, their work includes significant contributions within neurology, biochemistry, molecular biology, genetics, and organic chemistry subfields.

The primary topics covered in their research include:

  • Amyotrophic Lateral Sclerosis Research
  • Biochemical Acid Research Studies
  • Prion Diseases and Protein Misfolding
  • Parkinson's Disease Mechanisms and Treatments
  • Neurogenetic and Muscular Disorders Research
  • Sulfur-Based Synthesis Techniques

Their recent publications reflect an emphasis on amyotrophic lateral sclerosis (ALS), with studies appearing in notable journals as follows:

  • Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis, 2020, New England Journal of Medicine
  • Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis, 2020, Muscle & Nerve
  • Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial, 2022, Journal of Neurology Neurosurgery & Psychiatry

Frequent collaborators in these studies include the following coauthors:

  • Sabrina Paganoni
  • Suzanne Hendrix
  • James D. Berry
  • Michael A. Elliott
  • Samuel Maiser

Over the course of their career, Walter Gilbert has been recognized with several awards and honors, including:

  • Nobel Prize (1980) for contributions concerning the determination of base sequences in nucleic acids
  • Canada Gairdner International Award (1979)
  • Louisa Gross Horwitz Prize, Columbia University (1979)
  • Albert Lasker Award for Basic Medical Research, Lasker Foundation (1979)
  • Member of the National Academy of Sciences (1976)
  • Fellow of the American Physical Society (APS) (1998) with citation for fundamental studies of the biochemistry of nucleic acids with particular regard to recombinant DNA
  • Fellow of the Royal Society, United Kingdom (1987)
  • Fellow of the American Association for the Advancement of Science (AAAS) (multiple years: 1947, 1988)
  • Fellow of the American Academy of Arts and Sciences (1968)
  • Fellow of John Simon Guggenheim Memorial Foundation (1967)

Best Publications

  • Sequencing end-labeled DNA with base-specific chemical cleavages.

    Allan M. Maxam;Walter Gilbert

  • A new method for sequencing DNA

    Allan M. Maxam;Walter Gilbert

  • Genomic sequencing

    G M Church;W Gilbert

  • Origin of life: The RNA world

    Walter Gilbert

  • Why genes in pieces

    Walter Gilbert

  • Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

    Dipankar Sen;Walter Gilbert

  • Mapping adenines, guanines, and pyrimidines in RNA

    Helen Donis-Keller;Allan M. Maxam;Walter Gilbert

  • Molecular basis of base substitution hotspots in Escherichia coli.

    Christine Coulondre;Jeffrey H. Miller;Philip J. Farabaugh;Walter Gilbert

  • E. coli RNA polymerase interacts homologously with two different promoters

    Ulrich Siebenlist;Robert B. Simpson;Walter Gilbert

  • Nucleotide sequence of rous sarcoma virus

    Dennis E. Schwartz;Richard Tizard;Walter Gilbert

  • DNA sequencing at 40: past, present and future

    Jay Shendure;Shankar Balasubramanian;George M. Church;Walter Gilbert

  • A sodium-potassium switch in the formation of four-stranded G4-DNA

    Dipankar Sen;Walter Gilbert

  • ISOLATION OF THE LAC REPRESSOR

    Walter Gilbert;Benno Müller-Hill

  • Hepatitis B virus genes and their expression in E. coli.

    Mark Pasek;Tadaatsu Goto;Walter Gilbert;Barbara Zink

  • The evolution of genes: the chicken preproinsulin gene

    Francine Perler;Argiris Efstratiadis;Peter Lomedico;Walter Gilbert

  • A bacterial clone synthesizing proinsulin.

    Lydia Villa-Komaroff;Argiris Efstratiadis;Stephanie Broome;Peter Lomedico

  • B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo

    Anne Ephrussi;George M. Church;Susumu Tonegawa;Walter Gilbert

  • Unstable Ribonucleic Acid Revealed by Pulse Labelling of Escherichia Coli

    Francois Gros;H. Hiatt;Walter Gilbert;C. G. Kurland

  • Useful proteins from recombinant bacteria.

    Walter Gilbert;Lydia Villa-Komaroff

  • The limited universe of exons

    Robert L. Dorit;Walter Gilbert

Frequent Co-Authors

Scott William Roy
Scott William Roy San Francisco State University
Argiris Efstratiadis
Argiris Efstratiadis Biomedical Research Foundation of the Academy of Athens
Manyuan Long
Manyuan Long University of Chicago
George M. Church
George M. Church Harvard University
Winship Herr
Winship Herr University of Lausanne
Dipankar Sen
Dipankar Sen Simon Fraser University
Didier Y. R. Stainier
Didier Y. R. Stainier Max Planck Society
Richard D. Kolodner
Richard D. Kolodner University of California, San Diego
Laura F. Landweber
Laura F. Landweber Columbia University

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