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Genetics

D-Index
50
Citations
11468
World Ranking
3914
National Ranking
454

Overview

Jane Mellor is affiliated with the University of Oxford in the United Kingdom. Their research spans several domains within biochemistry, genetics, and molecular biology, with a significant focus on molecular biology. They have contributed to areas such as infectious diseases, physiology, endocrine and autonomic systems, and plant science.

The scientist's main research topics include:

  • RNA Research and Splicing
  • Circadian rhythm and melatonin
  • Genomics and Chromatin Dynamics
  • Gut microbiota and health
  • Fungal and yeast genetics research
  • Genetics, Aging, and Longevity in Model Organisms
  • Light effects on plants

Among their recent publications are:

  • H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner (2021, BMC Biology)
  • Cold-induced chromatin compaction and nuclear retention of clock mRNAs resets the circadian rhythm (2020, The EMBO Journal)
  • FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner (2020, bioRxiv, Cold Spring Harbor Laboratory)
  • 3D genomic capture of regulatory immuno-genetic profiles in COVID-19 patients for prognosis of severe COVID disease outcome (2021, bioRxiv, Cold Spring Harbor Laboratory)
  • Pharmacologically induced weight loss is associated with distinct gut microbiome changes in obese rats (2022, BMC Microbiology)

Jane Mellor frequently collaborates with a consistent group of coauthors, indicating active teamwork in their research projects. Notable frequent coauthors include Harry Fischl, André Furger, Andrew Angel, Alexandre Akoulitchev, and Paul T. Pfluger.

Their research output is often published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Yeast
  • BMC Biology
  • The EMBO Journal
  • Molecular Metabolism

Best Publications

  • Active genes are tri-methylated at K4 of histone H3

    Helena Santos-Rosa;Robert Schneider;Andrew J. Bannister;Julia Sherriff

  • Is H3K4me3 instructive for transcription activation

    Françoise S. Howe;Harry Fischl;Struan C. Murray;Jane Mellor

  • Gene loops juxtapose promoters and terminators in yeast.

    Justin M O'Sullivan;Sue Mei Tan-Wong;Antonin Morillon;Barbara Lee

  • Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae.

    J. Mellor;M.J. Dobson;N.A. Roberts;M.F. Tuite

  • Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin.

    Helena Santos-Rosa;Robert Schneider;Bradley E. Bernstein;Nickoletta Karabetsou

  • A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization.

    Triantaffyllos Gkikopoulos;Pieta Schofield;Vijender Singh;Marina Pinskaya

  • Dynamic Lysine Methylation on Histone H3 Defines the Regulatory Phase of Gene Transcription

    Antonin Morillon;Nickoletta Karabetsou;Anitha Nair;Jane Mellor

  • The Dynamics of Chromatin Remodeling at Promoters

    Jane Mellor

  • It Takes a PHD to Read the Histone Code

    Jane Mellor

  • Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

    Antonin Morillon;Nickoletta Karabetsou;Justin O'Sullivan;Nicholas Kent

  • Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

    Hanlin Zhang;Ghada Alsaleh;Jack Feltham;Yizhe Sun

  • CPF1, a yeast protein which functions in centromeres and promoters.

    J Mellor;W Jiang;M Funk;J Rathjen

  • Dynamic nucleosomes and gene transcription.

    Jane Mellor

  • A retrovirus-like strategy for expression of a fusion protein encoded by yeast transposon Ty1.

    Jane Mellor;Sandra M. Fulton;Melanie J. Dobson;Wilma Wilson

  • Reverse transcriptase activity and Ty RNA are associated with virus-like particles in yeast

    Jane Mellor;Michael H. Malim;Keith Gull;Mick F. Tuite

  • Roles for Ctk1 and Spt6 in regulating the different methylation states of histone H3 lysine 36.

    Michael L. Youdell;Kelby O. Kizer;Elena Kisseleva-Romanova;Stephen M. Fuchs

  • Efficient expression of the Saccharomyces cerevisiae PGK gene depends on an upstream activation sequence but does not require TATA sequences.

    J E Ogden;C Stanway;S Kim;J Mellor

  • The functions and relationships of Ty-VLP proteins in yeast reflect those of mammalian retroviral proteins.

    Sally E Adams;Jane Mellor;Keith Gull;Robert B Sim

  • In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p

    Nicholas A. Kent;Nickoletta Karabetsou;Panagiotis K. Politis;Jane Mellor

  • Factors affecting heterologous gene expression in Saccharomyces cerevisiae

    J. Mellor;M.J. Dobson;N.A. Roberts;A.J. Kingsman

Frequent Co-Authors

Alan J. Kingsman
Alan J. Kingsman Oxford BioMedica (United Kingdom)
Susan M. Kingsman
Susan M. Kingsman Oxford BioMedica (United Kingdom)
Tom Brown
Tom Brown University of Oxford
Afaf H. El-Sagheer
Afaf H. El-Sagheer University of Southampton
Mick F. Tuite
Mick F. Tuite University of Kent
Stuart L. Schreiber
Stuart L. Schreiber Harvard University
Michael H. Malim
Michael H. Malim King's College London
Colin R. Goding
Colin R. Goding University of Oxford
Nick J. Proudfoot
Nick J. Proudfoot University of Oxford
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute

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