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D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
17568
World Ranking
8153
National Ranking
136

Overview

Juan Sastre is affiliated with the University of Valencia in Spain. Their research focuses primarily on biochemistry, genetics, and molecular biology, with a significant number of publications also related to medicine. Key subfields of their work include molecular biology, surgery, immunology, cell biology, and biochemistry.

The main topics covered in Juan Sastre's research are:

  • Pancreatitis Pathology and Treatment
  • Redox biology and oxidative stress
  • Endoplasmic Reticulum Stress and Disease
  • Mitochondrial Function and Pathology
  • Folate and B Vitamins Research
  • Phagocytosis and Immune Regulation
  • Biomedical Research and Pathophysiology

The scientist has published in several prominent venues. The most frequent publication venues include:

  • Free Radical Biology and Medicine
  • Redox Biology
  • Antioxidants and Redox Signaling
  • The EMBO Journal
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry

Juan Sastre has collaborated extensively with a number of co-authors, including:

  • Salvador Pérez
  • Sergio Rius-Pérez
  • Pablo Martí-Andrés
  • Antonio Martínez-Ruiz
  • Isabela Finamor

Recent publications authored by or involving Juan Sastre cover a range of topics related to redox biology, oxidative stress, and cell death mechanisms. Notable recent papers are:

  • "Health position paper and redox perspectives - Disease burden by transportation noise" (2023, Redox Biology)
  • "p53 drives necroptosis via downregulation of sulfiredoxin and peroxiredoxin 3" (2022, Redox Biology)
  • "Mitochondrial Reactive Oxygen Species and Lytic Programmed Cell Death in Acute Inflammation" (2023, Antioxidants and Redox Signaling)
  • "Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer" (2020, Redox Biology)
  • "Importance of immunometabolic markers for the classification of patients with major depressive disorder using machine learning" (2022, Progress in Neuro-Psychopharmacology and Biological Psychiatry)

Best Publications

  • Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance

    Mari-Carmen Gomez-Cabrera;Elena Domenech;Marco Romagnoli;Alessandro Arduini

  • Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males

    Consuelo Borrás;Juan Sastre;David García-Sala;Ana Lloret

  • Decreasing xanthine oxidase‐mediated oxidative stress prevents useful cellular adaptations to exercise in rats

    Maria Carmen Gomez-Cabrera;Consuelo Borrás;Federico V. Pallardo;Juan Sastre

  • Preterm resuscitation with low oxygen causes less oxidative stress, inflammation, and chronic lung disease.

    Maximo Vento;Manuel Moro;Raquel Escrig;Luis Arruza

  • Mitochondrial oxidative stress plays a key role in aging and apoptosis.

    Juan Sastre;Federico V. Pallardó;José Viña

  • The role of mitochondrial oxidative stress in aging.

    Juan Sastre;Federico V Pallardó;José Viña

  • Mitochondria, oxidative stress and aging.

    Juan Sastre;Federico V. Pallardó;José García de la Asunción;José Viña

  • Oxidative stress in asphyxiated term infants resuscitated with 100% oxygen

    Máximo Vento;Miguel Asensi;Juan Sastre;Ana Lloret

  • Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA.

    J G de la Asuncion;A Millan;R Pla;L Bruseghini

  • Exhaustive physical exercise causes oxidation of glutathione status in blood: prevention by antioxidant administration.

    J. Sastre;M. Asensi;E. Gasco;F. V. Pallardo

  • Free radicals in exhaustive physical exercise: mechanism of production, and protection by antioxidants.

    Jose VinÑa;Mari-Carmen Gomez-Cabrera;Ana Lloret;Rafael Marquez

  • Why females live longer than males? Importance of the upregulation of longevity-associated genes by oestrogenic compounds

    Jose Viña;Consuelo Borrás;Juan Gambini;Juan Sastre

  • Room-Air Resuscitation Causes Less Damage to Heart and Kidney than 100% Oxygen

    Máximo Vento;Juan Sastre;Miguel A. Asensi;José Viña

  • 17beta-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFkappaB cascade.

    Consuelo Borrás;Juan Gambini;Ma Carmen Gómez-Cabrera;Juan Sastre

  • A Ginkgo Biloba Extract (EGb 761) Prevents Mitochondrial Aging by Protecting Against Oxidative Stress

    Juan Sastre;Arantxa Millan;Jose Garcia de la Asuncion;Rosa Pla

  • Aging of the liver: Age-associated mitochondrial damage in intact hepatocytes

    J Sastre;F V Pallardó;R Plá;A Pellín

  • Mechanism of free radical production in exhaustive exercise in humans and rats; role of xanthine oxidase and protection by allopurinol

    José Viña;Amparo Gimeno;Juan Sastre;Carmen Desco

  • Antibodies to carbonic anhydrase and IgG4 levels in idiopathic chronic pancreatitis: relevance for diagnosis of autoimmune pancreatitis

    L Aparisi;A Farre;L Gomez-Cambronero;J Martinez

  • Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro

    J. M. Esteve;J. Mompo;J. Garcia De La Asuncion;J. Sastre

  • Ratio of reduced to oxidized glutathione as indicator of oxidative stress status and DNA damage

    M Asensi;J Sastre;F V Pallardo;A Lloret

Frequent Co-Authors

Jose Viña
Jose Viña University of Valencia
Federico V. Pallardó
Federico V. Pallardó University of Valencia
Angel R. Nebreda
Angel R. Nebreda Institució Catalana de Recerca i Estudis Avançats
Richard J. Martin
Richard J. Martin Case Western Reserve University
George Perry
George Perry The University of Texas at San Antonio
Giuseppe Poli
Giuseppe Poli University of Turin
Ola Didrik Saugstad
Ola Didrik Saugstad Oslo University Hospital
Mark A. Smith
Mark A. Smith Case Western Reserve University
Michele C. Walsh
Michele C. Walsh Case Western Reserve University
Frank van Bel
Frank van Bel Utrecht University

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