World's Best Scientists 2026 revealed!
Award Badge
Molecular Biology
Spain
2026

D-Index & Metrics

Molecular Biology

D-Index
80
Citations
27680
World Ranking
989
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Spain Leader Award
  • 2025 - Research.com Molecular Biology in Spain Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Angel R. Nebreda is affiliated with the Institució Catalana de Recerca i Estudis Avançats in Spain. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, with a particular focus on molecular biology and oncology.

Their scholarly output includes recent papers covering a range of topics related to cellular signaling, cancer metastasis, and regulatory mechanisms in disease contexts. Notable publications include:

  • Diversity and versatility of p38 kinase signalling in health and disease, 2021, Nature Reviews Molecular Cell Biology
  • Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation, 2020, European Journal of Medicinal Chemistry
  • ERK1/2 Signaling Induces Upregulation of ANGPT2 and CXCR4 to Mediate Liver Metastasis in Colon Cancer, 2020, Cancer Research
  • The atypical CDK activator RingoA/Spy1 regulates exit from quiescence in neural stem cells, 2023, iScience
  • A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia, 2020, Blood Cancer Journal

Their research interests are reflected in the main topics they have explored, including:

  • Melanoma and MAPK Pathways
  • Computational Drug Discovery Methods
  • Ubiquitin and proteasome pathways
  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Protein Degradation and Inhibitors
  • Peptidase Inhibition and Analysis

The scientist has contributed to journals and platforms such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Proceedings of the National Academy of Sciences
  • Nature Communications
  • Nature Reviews Molecular Cell Biology

Frequent collaborators include Begoña Cánovas, Monica Cubillos-Rojas, Antoni Riéra, Nuria Martí Gutiérrez, and Elisabet Llonch. These coauthors have jointly contributed to various aspects of cellular signaling, molecular pathways, and disease mechanisms.

Angel R. Nebreda's research has garnered attention within the scientific community, demonstrated in citation counts notably for their 2021 publication on p38 kinase signalling. Their contributions span both experimental and computational methods in molecular biosciences.

An award recognizing their involvement in the broader molecular biology community is the membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Signal integration by JNK and p38 MAPK pathways in cancer development

    Erwin F. Wagner;Ángel R. Nebreda

  • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.

    John Rouse;Philip Cohen;Sylviane Trigon;Michel Morange

  • Mechanisms and functions of p38 MAPK signalling

    Ana Cuadrado;Angel R. Nebreda

  • TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

    Daniele V. F. Tauriello;Sergio Palomo-Ponce;Diana Stork;Antonio Berenguer-Llergo

  • p38 MAP kinases: beyond the stress response

    Angel R Nebreda;Almudena Porras

  • Essential Role of p38α MAP Kinase in Placental but Not Embryonic Cardiovascular Development

    Ralf H. Adams;Almudena Porras;Gema Alonso;Margaret Jones

  • Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

    Dmitry V. Bulavin;Oleg N. Demidov;Shin'ichi Saito;Paivikki Kauraniemi;Paivikki Kauraniemi

  • p38α MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis

    Ignacio Dolado;Aneta Swat;Nuria Ajenjo;Gabriella De Vita

  • Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.

    Ricardo M Biondi;Angel R Nebreda

  • A link between MAP kinase and p34cdc2/cyclin B during oocyte maturation: p90rsk phosphorylates and inactivates the p34cdc2 inhibitory kinase Myt1

    Amparo Palmer;Anne‐Claude Gavin;Angel R. Nebreda

  • Diversity and versatility of p38 kinase signalling in health and disease.

    Begoña Canovas;Angel R. Nebreda

  • Feedback control of the protein kinase TAK1 by SAPK2a/p38α

    Peter C.F. Cheung;David G. Campbell;Angel R. Nebreda;Philip Cohen

  • Regulation of the meiotic cell cycle in oocytes.

    Angel R Nebreda;Ingvar Ferby

  • p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation.

    Juan José Ventura;Stephan Tenbaum;Eusebio Perdiguero;Marion Huth

  • Regulation of skeletal muscle gene expression by p38 MAP kinases

    Frederic Lluís;Eusebio Perdiguero;Angel R. Nebreda;Pura Muñoz-Cánoves

  • Xkid, a Chromokinesin Required for Chromosome Alignment on the Metaphase Plate

    Celia Antonio;Ingvar Ferby;Heike Wilhelm;Margaret Jones

  • p38α Mitogen-activated Protein Kinase Sensitizes Cells to Apoptosis Induced by Different Stimuli

    Almudena Porras;Susana Zuluaga;Emma Black;Amparo Valladares

  • Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling.

    Brooke M. Emerling;Leonidas C. Platanias;Emma Black;Angel R. Nebreda

  • Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

    Panagiotis Galanos;Konstantinos Vougas;David Walter;Alexander Polyzos

  • p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint.

    Vanesa Lafarga;Ana Cuadrado;Isabel Lopez de Silanes;Rocio Bengoechea

Frequent Co-Authors

Vassilis G. Gorgoulis
Vassilis G. Gorgoulis National and Kapodistrian University of Athens
Juan Sastre
Juan Sastre University of Valencia
Anne-Claude Gavin
Anne-Claude Gavin University of Geneva
Philip Cohen
Philip Cohen University of Dundee
Matthias Gaestel
Matthias Gaestel Hannover Medical School
Reuben Kapur
Reuben Kapur Indiana University
J. Simon C. Arthur
J. Simon C. Arthur University of Dundee
Bernard Ducommun
Bernard Ducommun Federal University of Toulouse Midi-Pyrénées
Carlos G. Dotti
Carlos G. Dotti Spanish National Research Council
Manolis Pasparakis
Manolis Pasparakis University of Cologne

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology can open doors to a variety of interdisciplinary career pathways in science, education, healthcare, and research. Many students choose to widen their skills by pursuing flexible online programs that align with today’s evolving job market.

For those seeking broad scientific training, there are cheap online interdisciplinary studies degree options available, combining biological principles with subjects like chemistry, math, or healthcare. If you’re interested in the historical and ethical foundations of scientific progress, consider the cheapest online masters in history, which can enhance your understanding of the societal impact of scientific breakthroughs.

Careers outside traditional laboratory work—such as in data management or scientific librarianship—can benefit from pursuing the cheapest masters in library science, providing expertise in information organization and retrieval. Additionally, if you’re drawn to healthcare communication, especially with bio-related disorders, accredited online programs like accredited speech pathology programs may offer a fast, reputable route into clinical practice.

Diversifying your education with these online degrees can amplify your skill set and open new professional avenues within or beyond Molecular Biology.

Best Scientists Citing Angel R. Nebreda

Trending Scientists