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Molecular Biology

D-Index
64
Citations
15435
World Ranking
1734
National Ranking
21

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Francesc Posas is affiliated with Pompeu Fabra University in Spain and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research spans multiple subfields, including molecular biology, cell biology, plant science, electrical and electronic engineering, and oncology.

Their work encompasses a variety of specialized topics, reflecting a diverse range of interests within molecular and cellular processes. Key research topics include:

  • Fungal and yeast genetics research
  • Gene Regulatory Network Analysis
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • Bioinformatics and Genomic Networks
  • Single-cell and spatial transcriptomics

Posas has published papers in several renowned venues, frequently contributing to publications such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Nature Communications
  • International Journal of Molecular Sciences
  • Proceedings of the National Academy of Sciences

Some of the recent publications include:

  • "The p38 Pathway: From Biology to Cancer Therapy," 2020, International Journal of Molecular Sciences
  • "The HOG pathway and the regulation of osmoadaptive responses in yeast," 2022, FEMS Yeast Research
  • "LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions," 2021, Proceedings of the National Academy of Sciences
  • "Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies," 2022, Cancers
  • "A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress," 2020, Nucleic Acids Research

Collaborations are a significant aspect of Posas's research, with frequent co-authors including:

  • Eulàlia de Nadal
  • Carme Solé
  • Mariona Nadal-Ribelles
  • Pablo Latorre
  • Gerhard Seisenbacher

Among their recognitions, Francesc Posas is noted as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Yeast HOG1 MAP Kinase Cascade Is Regulated by a Multistep Phosphorelay Mechanism in the SLN1–YPD1–SSK1 “Two-Component” Osmosensor

    Francesc Posas;Susannah M Wurgler-Murphy;Tatsuya Maeda;Elizabeth A Witten

  • Controlling gene expression in response to stress

    Eulàlia de Nadal;Gustav Ammerer;Francesc Posas

  • Osmotic Activation of the HOG MAPK Pathway via Ste11p MAPKKK: Scaffold Role of Pbs2p MAPKK

    Francesc Posas;Haruo Saito

  • Response to hyperosmotic stress.

    Haruo Saito;Francesc Posas

  • The Transcriptional Response of Yeast to Saline Stress

    Francesc Posas;Francesc Posas;James R. Chambers;John A. Heyman;James P. Hoeffler

  • Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1.

    Paul Ferrigno;Francesc Posas;Deanna Koepp;Haruo Saito

  • Distributed biological computation with multicellular engineered networks

    Sergi Regot;Javier Macia;Núria Conde;Kentaro Furukawa

  • The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes

    Eulàlia de Nadal;Meritxell Zapater;Paula M. Alepuz;Paula M. Alepuz;Lauro Sumoy

  • Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator.

    Francesc Posas;Haruo Saito

  • Yeast Cdc42 GTPase and Ste20 PAK‐like kinase regulate Sho1‐dependent activation of the Hog1 MAPK pathway

    Desmond C. Raitt;Francesc Posas;Francesc Posas;Haruo Saito

  • Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1.

    Xavier Escoté;Meritxell Zapater;Josep Clotet;Francesc Posas

  • 3D-printing of transparent bio-microfluidic devices in PEG-DA

    Arturo Urrios;Cesar Parra-Cabrera;Nirveek Bhattacharjee;Alan M. Gonzalez-Suarez;Alan M. Gonzalez-Suarez

  • The p38 Pathway: From Biology to Cancer Therapy.

    Adrián Martínez-Limón;Manel Joaquin;María Caballero;Francesc Posas

  • Dealing with osmostress through MAP kinase activation

    Eulàlia de Nadal;Paula M Alepuz;Francesc Posas

  • Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress

    Markus Proft;Amparo Pascual-Ahuir;Eulàlia de Nadal;Joaquin Ariño

  • Osmostress‐induced transcription by Hot1 depends on a Hog1‐mediated recruitment of the RNA Pol II

    Paula M. Alepuz;Paula M. Alepuz;Eulàlia de Nadal;Meritxell Zapater;Gustav Ammerer

  • A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

    Mutsuhiro Takekawa;Francesc Posas;Haruo Saito

  • The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress.

    Clara Bermejo;Estefanía Rodríguez;Raúl García;Jose M. Rodríguez-Peña

  • Signal transduction by MAP kinase cascades in budding yeast.

    Francesc Posas;Mutsuhiro Takekawa;Haruo Saito

  • The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.

    Michael Thorsen;Yujun Di;Carolina Tängemo;Montserrat Morillas

Frequent Co-Authors

Joaquín Ariño
Joaquín Ariño Autonomous University of Barcelona
Ricard V. Solé
Ricard V. Solé Pompeu Fabra University
Haruo Saito
Haruo Saito University of Tokyo
Gustav Ammerer
Gustav Ammerer University of Vienna
Edda Klipp
Edda Klipp Humboldt-Universität zu Berlin
Matthias Peter
Matthias Peter ETH Zurich
Andrés Aguilera
Andrés Aguilera University of Seville
Lars M. Steinmetz
Lars M. Steinmetz Stanford University
Ramón Serrano
Ramón Serrano Universitat Politècnica de València
Stefan Hohmann
Stefan Hohmann Chalmers University of Technology

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