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Neuroscience

D-Index
88
Citations
27257
World Ranking
1212
National Ranking
618

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2016 - Member of the National Academy of Sciences
  • 2011 - Fellow of the American Academy of Arts and Sciences
  • 2009 - Member of the National Academy of Medicine (NAM)

Overview

Amita Sehgal is affiliated with the University of Pennsylvania in the United States. Their research is primarily centered in the field of Neuroscience, with a significant focus on several subfields including Endocrine and Autonomic Systems, Cellular and Molecular Neuroscience, Cognitive Neuroscience, Physiology, and Molecular Biology.

Their research topics encompass a range of themes related to biological rhythms and neurobiology. Key topics include:

  • Circadian rhythm and melatonin
  • Neurobiology and Insect Physiology Research
  • Sleep and Wakefulness Research
  • Dietary Effects on Health
  • Genetics, Aging, and Longevity in Model Organisms
  • Photoreceptor and optogenetics research
  • Epigenetics and DNA Methylation

Sehgal has a strong publication record in reputable venues, frequently publishing in the following journals and platforms:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Proceedings of the National Academy of Sciences
  • Journal of Biological Rhythms
  • Nature Communications

Several coauthors have been frequent collaborators in Sehgal's work, including:

  • Yongjun Li (18 publications)
  • Shirley Zhang (17 publications)
  • Zhifeng Yue (12 publications)
  • Cynthia T. Hsu (10 publications)
  • Sara B. Noya (9 publications)

Recent notable papers by Sehgal include:

  • "Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System" (2020, Cell Metabolism)
  • "Circadian Rhythms, Disease and Chronotherapy" (2021, Journal of Biological Rhythms)
  • "A circadian clock regulates efflux by the blood-brain barrier in mice and human cells" (2021, Nature Communications)
  • "A neuron-glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis" (2024, Nature Neuroscience)
  • "Availability of food determines the need for sleep in memory consolidation" (2020, Nature)

Amita Sehgal has received several distinctions over the course of their career. Awards include:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2016
  • Member of the National Academy of Sciences, 2016
  • Fellow of the American Academy of Arts and Sciences, 2011
  • Member of the National Academy of Medicine (NAM), 2009

Best Publications

  • Expression and structure of the human NGF receptor

    Dan Johnson;Anthony Lanahan;C.Randy Buck;Amita Sehgal

  • Rest in Drosophila Is a Sleep-like State

    Joan C Hendricks;Stefanie M Finn;Karen A Panckeri;Jessica Chavkin

  • Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless

    Amita Sehgal;Jeffrey L. Price;Bernice Man;Michael W. Young

  • Gene transfer and molecular cloning of the human NGF receptor

    MV Chao;MA Bothwell;AH Ross;H Koprowski

  • Pharmacological Rescue of Synaptic Plasticity, Courtship Behavior, and Mushroom Body Defects in a Drosophila Model of Fragile X Syndrome

    Sean M.J. McBride;Catherine H. Choi;Yan Wang;David Liebelt

  • Regulation of CLOCK and MOP4 by Nuclear Hormone Receptors in the Vasculature: A Humoral Mechanism to Reset a Peripheral Clock

    Peter McNamara;Sang beom Seo;Radu Daniel Rudic;Amita Sehgal

  • Circadian Rhythms and Sleep in Drosophila melanogaster

    Christine Dubowy;Amita Sehgal

  • Sleep in Drosophila is regulated by adult mushroom bodies

    William J. Joiner;Amanda Crocker;Benjamin H. White;Amita Sehgal

  • Regulation of the Drosophila Protein Timeless Suggests a Mechanism for Resetting the Circadian Clock by Light

    Melissa Hunter-Ensor;Andrea Ousley;Amita Sehgal

  • Isolation of timeless by PER Protein Interaction: Defective Interaction Between timeless Protein and Long-Period Mutant PERL

    Nicholas Gekakis;Lino Saez;Anne-Marie Delahaye-Brown;Michael P. Myers

  • Block in nuclear localization of period protein by a second clock mutation, timeless

    Leslie B. Vosshall;Jeffrey L. Price;Amita Sehgal;Lino Saez

  • Rhythmic Expression of timeless: A Basis for Promoting Circadian Cycles in period Gene Autoregulation

    Amita Sehgal;Adrian Rothenfluh-Hilfiker;Melissa Hunter-Ensor;Yifeng Chen

  • Genetics of Sleep and Sleep Disorders

    Amita Sehgal;Emmanuel Mignot

  • A Drosophila model for age-associated changes in sleep:wake cycles

    Kyunghee Koh;Joshua M. Evans;Joan C. Hendricks;Amita Sehgal

  • Identification of SLEEPLESS, a Sleep-Promoting Factor

    Kyunghee Koh;William J. Joiner;Mark N. Wu;Zhifeng Yue

  • Circadian Rhythms, Sleep, and Disorders of Aging.

    Joanna Mattis;Amita Sehgal

  • Identification of a Neural Circuit that Underlies the Effects of Octopamine on Sleep:Wake Behavior

    Amanda Crocker;Mohammad Shahidullah;Irwin B. Levitan;Amita Sehgal

  • Positional cloning and sequence analysis of the Drosophila clock gene, timeless

    Michael P. Myers;Karen Wager-Smith;Cedric S. Wesley;Michael W. Young

  • JETLAG Resets the Drosophila Circadian Clock by Promoting Light-Induced Degradation of TIMELESS

    Kyunghee Koh;Xiangzhong Zheng;Amita Sehgal

  • Regulation of feeding and metabolism by neuronal and peripheral clocks in Drosophila

    Kanyan Xu;Xiangzhong Zheng;Amita Sehgal

  • A role for the proteasome in the light response of the timeless clock protein.

    Nirinjini Naidoo;Wei Song;Melissa Hunter-Ensor;Amita Sehgal

  • Role of Molecular Oscillations in Generating Behavioral Rhythms in Drosophila

    Zhaohai Yang;Amita Sehgal

  • A constitutive promoter directs expression of the nerve growth factor receptor gene.

    Amita Sehgal;Nila Patil;Moses Chao

Frequent Co-Authors

Michael W. Young
Michael W. Young Rockefeller University
Moses V. Chao
Moses V. Chao New York University
Leslie B. Vosshall
Leslie B. Vosshall Rockefeller University
Samer Hattar
Samer Hattar National Institutes of Health
Peter Meerlo
Peter Meerlo University of Groningen
Yasufumi Shigeyoshi
Yasufumi Shigeyoshi Kindai University
Nirinjini Naidoo
Nirinjini Naidoo University of Pennsylvania
Max B. Kelz
Max B. Kelz University of Pennsylvania
Mark Bothwell
Mark Bothwell University of Washington
Ian D. Krantz
Ian D. Krantz Children's Hospital of Philadelphia

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