World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
106
Citations
37458
World Ranking
6589
National Ranking
185

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Estrogen
  • Internal medicine

Evan R. Simpson mostly deals with Aromatase, Internal medicine, Endocrinology, Estrogen and Aromatase deficiency. His studies deal with areas such as Adipose tissue, Molecular biology and Cancer research as well as Aromatase. His study on Follicular phase, Antral follicle, Endocrine system and Menopause is often connected to Extragonadal as part of broader study in Internal medicine.

His Endocrinology research integrates issues from Knockout mouse and Germ cell. Evan R. Simpson has researched Estrogen in several fields, including Intracrine, Hormone, Receptor and Estrogen receptor, Estrogen receptor alpha. In his study, Metabolic syndrome is inextricably linked to Testosterone, which falls within the broad field of Aromatase deficiency.

His most cited work include:

  • Aromatase Cytochrome P450, The Enzyme Responsible for Estrogen Biosynthesis* (1288 citations)
  • Estrogen and spermatogenesis. (674 citations)
  • Sources of estrogen and their importance. (672 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Aromatase, Estrogen and Adipose tissue. In his study, which falls under the umbrella issue of Internal medicine, CRTC2 is strongly linked to Protein kinase A. He combines subjects such as Receptor, Knockout mouse, AMPK and Estrogen receptor alpha with his study of Endocrinology.

The study incorporates disciplines such as Testosterone, Molecular biology and Cancer research, Stromal cell in addition to Aromatase. His research in Estrogen intersects with topics in Hypothalamus, Intracrine, Menopause and Transcription factor. The concepts of his Adipose tissue study are interwoven with issues in Promoter, Response element, Dihydrotestosterone and Forskolin.

He most often published in these fields:

  • Internal medicine (93.16%)
  • Endocrinology (90.00%)
  • Aromatase (88.42%)

What were the highlights of his more recent work (between 2011-2019)?

  • Internal medicine (93.16%)
  • Endocrinology (90.00%)
  • Aromatase (88.42%)

In recent papers he was focusing on the following fields of study:

Evan R. Simpson mainly focuses on Internal medicine, Endocrinology, Aromatase, Breast cancer and Estrogen. Evan R. Simpson interconnects AMPK and Protein kinase A in the investigation of issues within Endocrinology. His Aromatase research incorporates elements of Molecular biology, CRTC2, Cell biology, Regulation of gene expression and Transcription.

His Breast cancer study combines topics from a wide range of disciplines, such as Inflammation, Cancer research, Obesity and Oncology. His work on Phytoestrogens as part of general Estrogen study is frequently linked to Erythrina lysistemon, therefore connecting diverse disciplines of science. His Adipose tissue research is multidisciplinary, relying on both Stromal cell and Endocrine system.

Between 2011 and 2019, his most popular works were:

  • p53: protection against tumor growth beyond effects on cell cycle and apoptosis (114 citations)
  • p53: protection against tumor growth beyond effects on cell cycle and apoptosis (114 citations)
  • Research resource: nuclear receptors as transcriptome: discriminant and prognostic value in breast cancer. (65 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

Evan R. Simpson focuses on Breast cancer, Internal medicine, Aromatase, Endocrinology and Adipose tissue. His Breast cancer research is multidisciplinary, incorporating elements of Inflammation and Cancer research. His research on Internal medicine focuses in particular on Lipogenesis.

His research investigates the link between Aromatase and topics such as Regulation of gene expression that cross with problems in Synaptic plasticity, Aromatase inhibitor and Candidate gene. His primary area of study in Endocrinology is in the field of Estrogen. His studies in Estrogen integrate themes in fields like Prostaglandin E2 and Response element.

Best Publications

  • Aromatase Cytochrome P450, The Enzyme Responsible for Estrogen Biosynthesis*

    Evan R. Simpson;Mala S. Mahendroo;Gary D. Means;Michael W. Kilgore

  • Sources of estrogen and their importance.

    E.R Simpson

  • Estrogen and spermatogenesis.

    Liza O’Donnell;Kirsten M. Robertson;Kirsten M. Robertson;Margaret E. Jones;Evan R. Simpson

  • Aromatase—A Brief Overview

    Evan R Simpson;Colin Clyne;Gary Rubin;Wah Chin Boon

  • Control of mammary stem cell function by steroid hormone signalling

    Marie Liesse Asselin-Labat;François Vaillant;Julie M. Sheridan;Bhupinder Pal

  • Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene

    Kirsten M. Robertson;Liza O’Donnell;Margaret E. E. Jones;Sarah J. Meachem

  • Female androgen insufficiency: the princeton consensus statement on definition, classification, and assessment

    Gloria Bachmann;John Bancroft;Glenn Braunstein;Henry Burger

  • History of Aromatase: Saga of an Important Biological Mediator and Therapeutic Target

    R. J. Santen;H. Brodie;E. R. Simpson;P. K. Siiteri

  • Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment

    Laura Maffei;Yoko Murata;Vincenzo Rochira;Gloria Tubert

  • Assay of aromatase activity.

    Edwin D. Lephart;Evan R. Simpson

  • ESTROGEN - THE GOOD, THE BAD, AND THE UNEXPECTED

    Evan R Simpson;Marie Louise Misso;Kylie Narelle Hewitt;Rachel Anne Hill

  • The role of local estrogen biosynthesis in males and females.

    Evan Simpson;Gary Rubin;Colin Clyne;Kirsten Robertson

  • Liver Receptor Homologue-1 (LRH-1) Regulates Expression of Aromatase in Preadipocytes

    Colin D. Clyne;Caroline J. Speed;Jiong Zhou;Evan R. Simpson

  • p53: protection against tumor growth beyond effects on cell cycle and apoptosis

    Xuyi Wang;Evan Rutherford Simpson;Kristy A Brown;Kristy A Brown

  • Update on estrogen signaling

    Zhang Weihua;Sandra Andersson;Guojun Cheng;Evan R. Simpson

  • Anti-Müllerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells.

    Laura Pellatt;Suman Rice;Nafi Dilaver;Amira Heshri

  • Bone Has a Sexually Dimorphic Response to Aromatase Deficiency

    Orhan K. Öz;Joseph E. Zerwekh;Carolyn Fisher;Kathy Graves

  • An age-related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene.

    Kara L. Britt;Ann E. Drummond;Victoria A. Cox;Mitzilee Dyson

  • Postnatal Development of an Estradiol-Kisspeptin Positive Feedback Mechanism Implicated in Puberty Onset

    Jenny Clarkson;Wah Chin Boon;Evan R. Simpson;Allan E. Herbison

  • Aromatase: biologic relevance of tissue-specific expression.

    Evan R Simpson

Frequent Co-Authors

Susan R. Davis
Susan R. Davis Monash University
Hironobu Sasano
Hironobu Sasano Tohoku University
Jock K. Findlay
Jock K. Findlay Hudson Institute of Medical Research
Serdar E. Bulun
Serdar E. Bulun Northwestern University
John W. Funder
John W. Funder Hudson Institute of Medical Research
Gregory R. Steinberg
Gregory R. Steinberg McMaster University
Wayne D. Tilley
Wayne D. Tilley University of Adelaide
Geoffrey J. Lindeman
Geoffrey J. Lindeman Peter MacCallum Cancer Centre
George E. O. Muscat
George E. O. Muscat University of Queensland
Maarten van den Buuse
Maarten van den Buuse La Trobe University

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