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Stephen J. Lye

Stephen J. Lye

D-Index & Metrics

Medicine

D-Index
87
Citations
27076
World Ranking
13671
National Ranking
563

Overview

Stephen J. Lye is affiliated with the University of Toronto in Canada and is active in the field of Medicine, with a focus on Pediatrics, Perinatology and Child Health, Obstetrics and Gynecology, Public Health, Environmental and Occupational Health, General Health Professions, and Immunology.

Their research extensively covers topics such as:

  • Pregnancy and preeclampsia studies
  • Reproductive System and Pregnancy
  • Birth, Development, and Health
  • Preterm Birth and Chorioamnionitis
  • Child Nutrition and Water Access
  • Obesity, Physical Activity, Diet
  • Maternal Mental Health During Pregnancy and Postpartum

Stephen J. Lye has contributed to several recent papers, including:

  • Effects of the Global Coronavirus Disease-2019 Pandemic on Early Childhood Development: Short- and Long-Term Risks and Mitigating Program and Policy Actions, 2020, The Journal of Pediatrics
  • Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia, 2020, American Journal of Obstetrics and Gynecology
  • Efficient derivation of human trophoblast stem cells from primed pluripotent stem cells, 2021, Science Advances
  • Supporting Child Development Through Parenting Interventions in Low- to Middle-Income Countries: An Updated Systematic Review, 2021, Frontiers in Public Health
  • Myometrial activation: Novel concepts underlying labor, 2020, Placenta

The frequent co-authors collaborating with Stephen J. Lye include:

  • Shane A. Norris
  • Stephen G. Matthews
  • Catherine E. Draper
  • Oksana Shynlova
  • Caroline Dunk

The notable publication venues for Stephen J. Lye's work are:

  • American Journal of Obstetrics and Gynecology
  • Placenta
  • Cells
  • bioRxiv (Cold Spring Harbor Laboratory)
  • BMJ Open

Best Publications

  • Nurturing care: promoting early childhood development

    Pia R Britto;Stephen J Lye;Kerrie Proulx;Aisha K Yousafzai

  • ENDOCRINE AND PARACRINE REGULATION OF BIRTH AT TERM AND PRETERM

    John R.G. Challis;Stephen G. Matthews;William Gibb;William Gibb;Stephen J. Lye

  • Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3

    Isabella Caniggia;Homa Mostachfi;Jennifer Winter;Max Gassmann

  • Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsia.

    I. Caniggia;J. Winter;S.J. Lye;M. Post

  • Inhibition of TGF-β3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies

    Isabella Caniggia;Sorina Grisaru-Gravnosky;Maciej Kuliszewsky;Martin Post

  • Prostaglandins and mechanisms of preterm birth

    John R G Challis;Deborah M Sloboda;Nadia Alfaidy;Steven J Lye

  • Early childhood development: the foundation of sustainable development

    Bernadette Daelmans;Gary L. Darmstadt;Joan Lombardi;Maureen M. Black;Maureen M. Black

  • Effects of the Global Coronavirus Disease-2019 Pandemic on Early Childhood Development: Short- and Long-Term Risks and Mitigating Program and Policy Actions.

    Hirokazu Yoshikawa;Alice J. Wuermli;Pia Rebello Britto;Benard Dreyer

  • Macrophages Infiltrate the Human and Rat Decidua During Term and Preterm Labor: Evidence That Decidual Inflammation Precedes Labor

    Sarah Hamilton;Yasamin Oomomian;Gillian Stephen;Oksana Shynlova

  • Expression of the multidrug resistance P-glycoprotein, (ABCB1 glycoprotein) in the human placenta decreases with advancing gestation.

    M. Sun;J. Kingdom;D. Baczyk;Stephen Lye

  • Integration of endocrine and mechanical signals in the regulation of myometrial functions during pregnancy and labour.

    Oksana Shynlova;Prudence Tsui;Prudence Tsui;Shabana Jaffer;Shabana Jaffer;Stephen J. Lye

  • Activin Is a Local Regulator of Human Cytotrophoblast Cell Differentiation

    Isabella Caniggia;Stephen J. Lye;James C. Cross

  • Reduced placental villous tree elaboration in small-for-gestational-age pregnancies: relationship with umbilical artery Doppler waveforms.

    Moira R. Jackson;Anne J. Walsh;Robert J. Morrow;Brendan M. Muller

  • Endoglin regulates trophoblast differentiation along the invasive pathway in human placental villous explants.

    I. Caniggia;C. V. Taylor;J. W. K. Ritchie;S. J. Lye

  • Physiologic Uterine Inflammation and Labor Onset: Integration of Endocrine and Mechanical Signals

    Oksana Shynlova;Yu-Hui Lee;Yu-Hui Lee;Khetsopon Srikhajon;Stephen J Lye

  • Genome-wide Association and Longitudinal Analyses Reveal Genetic Loci Linking Pubertal Height Growth, Pubertal Timing, and Childhood Adiposity

    Diana L. Cousminer;Diane J. Berry;Nicholas J. Timpson;Wei Ang

  • Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast.

    D. Baczyk;S. Drewlo;L. Proctor;C. Dunk

  • Expression of connexin-43 and connexin-26 in the rat myometrium during pregnancy and labor is differentially regulated by mechanical and hormonal signals.

    Che-Wei Ou;Angela Orsino;Stephen J. Lye

  • Understanding Preterm Labor

    John R. G. Challis;Stephen J. Lye;William Gibb;Wendy Whittle

  • Genetic epidemiologic studies of preterm birth: guidelines for research.

    Craig E. Pennell;Craig E. Pennell;Bo Jacobsson;Bo Jacobsson;Scott M. Williams;Rebecca M. Buus

Frequent Co-Authors

Craig E. Pennell
Craig E. Pennell University of Newcastle Australia
Stephen G. Matthews
Stephen G. Matthews University of Toronto
John R. G. Challis
John R. G. Challis University of Toronto
Lyle J. Palmer
Lyle J. Palmer University of Adelaide
John Kingdom
John Kingdom University of Toronto
Nicole M. Warrington
Nicole M. Warrington University of Queensland
Chun Peng
Chun Peng York University
Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Martin Post
Martin Post University of Toronto
John P. Newnham
John P. Newnham University of Western Australia

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