World's Best Scientists 2026 revealed!
John R. G. Challis

John R. G. Challis

D-Index & Metrics

Medicine

D-Index
85
Citations
26118
World Ranking
14629
National Ranking
609

Overview

John R. G. Challis is affiliated with the University of Toronto in Canada and has contributed to research primarily in the fields of Medicine and Immunology and Microbiology. Their work spans several subfields, including Epidemiology, Pediatrics, Perinatology and Child Health, Obstetrics and Gynecology, Immunology, and Microbiology.

The scientist's research topics cover a range of issues related to reproductive health and development. These include:

  • Preterm Birth and Chorioamnionitis
  • Birth, Development, and Health
  • Pregnancy and Preeclampsia Studies
  • Reproductive System and Pregnancy
  • Reproductive Tract Infections Research
  • Urinary Tract Infections Management
  • Health, Environment, Cognitive Aging

Recent publications represent a diverse set of research areas and include the following papers:

  • Effect of Oral Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on the Vaginal Microbiota, Cytokines and Chemokines in Pregnant Women, 2020, published in Nutrients
  • Early life risk and resiliency factors and their influences on developmental outcomes and disease pathways: a rapid evidence review of systematic reviews and meta-analyses, 2020, published in Journal of Developmental Origins of Health and Disease
  • Image-based Stability Quantification, 2022, published in arXiv (Cornell University)

Challis has collaborated frequently with a number of coauthors, notably:

  • Felice Petraglia
  • Viola Seravalli
  • Mariarosaria Di Tommaso
  • Siwen Yang
  • Gregor Reid

The scientist has published in several well-regarded venues, including:

  • Nutrients
  • Journal of Developmental Origins of Health and Disease
  • arXiv (Cornell University)

Best Publications

  • ENDOCRINE AND PARACRINE REGULATION OF BIRTH AT TERM AND PRETERM

    John R.G. Challis;Stephen G. Matthews;William Gibb;William Gibb;Stephen J. Lye

  • Inflammation and Pregnancy

    John R. Challis;Charles J. Lockwood;Leslie Myatt;Jane E. Norman

  • Endocrine control of parturition

    GD Thorburn;John Challis

  • The Control of Labor

    E. R. Norwitz;J. N. Robinson;J. R.G. Challis

  • The expression of insulin-like growth factor (IGF) and IGF-binding protein (IGFBP) genes in the human placenta and membranes: evidence for IGF-IGFBP interactions at the feto-maternal interface

    V. K. M. Han;N. Bassett;J. Walton;J. R. G. Challis

  • Prostaglandins and mechanisms of preterm birth

    John R G Challis;Deborah M Sloboda;Nadia Alfaidy;Steven J Lye

  • The fetal placental hypothalamic-pituitary-adrenal (HPA) axis, parturition and post natal health.

    J.R.G. Challis;J.R.G. Challis;D.M. Sloboda;D.M. Sloboda;S.G. Matthews;S.G. Matthews;A. Holloway;A. Holloway

  • Steroids Modulate Corticotropin-Releasing Hormone Production in Human Fetal Membranes and Placenta*

    S. A. Jones;A. N. Brooks;J. R. G. Challis

  • Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in human placenta and fetal membranes in relation to preterm and term labor

    Ping Xu;Nadia Alfaidy;John R G Challis

  • MATURATION AND ACTIVATION OF HYPOTHALAMIC-PITUITARY-ADRENAL FUNCTION IN FETAL SHEEP

    J. R. G. Challis;A. N. Brooks

  • A periconceptional nutritional origin for noninfectious preterm birth.

    Frank H Bloomfield;Frank H Bloomfield;Frank H Bloomfield;Mark H Oliver;Mark H Oliver;Mark H Oliver;Paul Hawkins;Paul Hawkins;Paul Hawkins;Melanie Campbell;Melanie Campbell;Melanie Campbell

  • Expression of natural antimicrobials by human placenta and fetal membranes.

    A.E. King;A. Paltoo;R.W. Kelly;J.-M. Sallenave

  • Tihe Concentrations of Progesterone, Estrone and Estradiol-17β in the Plasma of Pregnant Rabbits

    John R. G. Challis;I. John Davies;Kenneth J. Ryan

  • SHARP INCREASE IN FREE CIRCULATING OESTROGENS IMMEDIATELY BEFORE PARTURITION IN SHEEP

    J. R. G. Challis

  • Neuroendocrine Mechanisms in Pregnancy and Parturition

    Felice Petraglia;Alberto Imperatore;John R. G. Challis

  • Concentrations of oestrogen and progesterone in the plasma of non-pregnant, pregnant and lactating guinea-pigs.

    J. R. G. Challis;R. B. Heap;Doreen V. Illingworth

  • Programming effects in sheep of prenatal growth restriction and glucocorticoid exposure

    Timothy J. M. Moss;Deborah M. Sloboda;Lyle C. Gurrin;Richard Harding

  • Changes in the synthesis and metabolism of prostaglandins by human fetal membranes and decidua at labor

    Karolina A. Skinner;Karolina A. Skinner;John R.G. Challis;John R.G. Challis

  • Differential Expression of 11β-Hydroxysteroid Dehydrogenase Types 1 and 2 in Human Placenta and Fetal Membranes1

    Kang Sun;Kaiping Yang;Kaiping Yang;John R. G. Challis

  • Fetal sex and preterm birth

    John Challis;John Newnham;F. Petraglia;M. Yeganegi

Frequent Co-Authors

Stephen J. Lye
Stephen J. Lye University of Toronto
Stephen G. Matthews
Stephen G. Matthews University of Toronto
Gregor Reid
Gregor Reid University of Western Ontario
Kenneth J. Ryan
Kenneth J. Ryan Harvard University
John P. Newnham
John P. Newnham University of Western Australia
Jane E. Harding
Jane E. Harding University of Auckland
Geoffrey L. Hammond
Geoffrey L. Hammond University of British Columbia
Felice Petraglia
Felice Petraglia University of Florence
Peter D. Gluckman
Peter D. Gluckman University of Auckland
Edwin E. Daniel
Edwin E. Daniel University of Alberta

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