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Molecular Biology

D-Index
42
Citations
8357
World Ranking
3010
National Ranking
1431

Overview

Patricia Wadsworth is affiliated with the University of Massachusetts Amherst in the United States and has focused their research on topics mainly within biochemistry, genetics, and molecular biology. Their scholarly output includes a significant emphasis on cell biology and molecular biology, with additional contributions to biophysics, plant science, and structural biology.

The scientist's research interests concentrate on microtubule and mitosis dynamics, protist diversity and phylogeny, photosynthetic processes and mechanisms, ubiquitin and proteasome pathways, cellular transport and secretion, advanced fluorescence microscopy techniques, and plant molecular biology research.

Frequent collaborators within their research include Carline Fermino do Rosário, Katrina Velle, Lillian K. Fritz-Laylin, Ying Zhang, and Jennifer Stadnicki.

Patricia Wadsworth's publications have been featured in venues such as Cytoskeleton, bioRxiv (Cold Spring Harbor Laboratory), Current Protocols, UNC Libraries, and the Biophysical Journal.

Recent papers include the following:

  • "Naegleria's mitotic spindles are built from unique tubulins and highlight core spindle features," 2022, Current Biology
  • "The multifunctional spindle midzone in vertebrate cells at a glance," 2021, Journal of Cell Science
  • "A OneStep Solution to Fix and Stain Cells for Correlative Live and Fixed Microscopy," 2021, Current Protocols
  • "Analysis of the treadmilling model during metaphase of mitosis using fluorescence redistribution after photobleaching," 2020, UNC Libraries
  • "Lateral and longitudinal compaction of PRC1 overlap zones drives stabilization of interzonal microtubules," 2023, Molecular Biology of the Cell

Best Publications

  • Taxol suppresses dynamics of individual microtubules in living human tumor cells

    Anne Marie C. Yvon;Patricia Wadsworth;Mary Ann Jordan

  • Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin.

    Nasser M. Rusan;Carey J. Fagerstrom;Anne-Marie C. Yvon;Patricia Wadsworth

  • Myosin-II-dependent localization and dynamics of F-actin during cytokinesis.

    Kausalya Murthy;Patricia Wadsworth

  • Molecular Requirements for Kinetochore-Associated Microtubule Formation in Mammalian Cells

    U. Serdar Tulu;Carey Fagerstrom;Nick P. Ferenz;Patricia Wadsworth

  • Kinetochore Dynein Is Required for Chromosome Motion and Congression Independent of the Spindle Checkpoint

    Zhenye Yang;U. Serdar Tulu;Patricia Wadsworth;Conly L. Rieder;Conly L. Rieder

  • Observation and quantification of individual microtubule behavior in vivo: microtubule dynamics are cell-type specific.

    E Shelden;P Wadsworth

  • Microtubule dynamics in living dividing plant cells: confocal imaging of microinjected fluorescent brain tubulin.

    Dahong Zhang;Patricia Wadsworth;Peter K. Hepler

  • Centrosome maturation: Measurement of microtubule nucleation throughout the cell cycle by using GFP-tagged EB1

    Michelle Piehl;U. Serdar Tulu;Pat Wadsworth;Lynne Cassimeris

  • Quantification of microtubule dynamics in living plant cells using fluorescence redistribution after photobleaching

    J.M. Hush;P. Wadsworth;D.A. Callaham;P.K. Hepler

  • Vinblastine suppresses dynamics of individual microtubules in living interphase cells.

    Rama Dhamodharan;M. A. Jordan;D. Thrower;L. Wilson

  • Mitotic functions of kinesin-5.

    Nick P. Ferenz;Alyssa Gable;Pat Wadsworth

  • Noscapine Alters Microtubule Dynamics in Living Cells and Inhibits the Progression of Melanoma

    Jaren W Landen;Roland Lang;Steve J McMahon;Nasser M Rusan

  • Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport

    Nasser M. Rusan;U. Serdar Tulu;Carey Fagerstrom;Patricia Wadsworth

  • E pluribus unum: towards a universal mechanism for spindle assembly

    Patricia Wadsworth;Alexey Khodjakov

  • Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells.

    U.S. Tulu;N.M. Rusan;P. Wadsworth

  • Kinesin-5 Regulation and Function in Mitosis

    Barbara J. Mann;Patricia Wadsworth

  • Dynamics of Microfilaments are Similar, but Distinct from Microtubules During Cytokinesis in Living, Dividing Plant-Cells

    Dahong Zhang;Patricia Wadsworth;Peter K. Hepler

  • Modulation of microtubule dynamic instability in vivo by brain microtubule associated proteins

    Rama Dhamodharan;P. Wadsworth

  • Centrosome reorientation in wound-edge cells is cell type specific

    Anne-Marie C. Yvon;Jonathan W. Walker;Barbara Danowski;Carey Fagerstrom

  • SV40 VP2 and VP3 Insertion into ER Membranes Is Controlled by the Capsid Protein VP1: Implications for DNA Translocation out of the ER

    Robert Daniels;Nasser M. Rusan;Patricia Wadsworth;Daniel N. Hebert

Frequent Co-Authors

Alfred J. Crosby
Alfred J. Crosby University of Massachusetts Amherst
Lynne Cassimeris
Lynne Cassimeris Lehigh University
Peter K. Hepler
Peter K. Hepler University of Massachusetts Amherst
Conly L. Rieder
Conly L. Rieder New York State Department of Health
Angus I. Lamond
Angus I. Lamond University of Dundee
Alexey Khodjakov
Alexey Khodjakov New York State Department of Health
Edward D. Salmon
Edward D. Salmon University of North Carolina at Chapel Hill
Mary Ann Jordan
Mary Ann Jordan University of California, Santa Barbara
Tobias I. Baskin
Tobias I. Baskin University of Massachusetts Amherst
Donald P. Bottaro
Donald P. Bottaro National Institutes of Health

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