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Manuel R. Teixeira

Manuel R. Teixeira

D-Index & Metrics

Medicine

D-Index
82
Citations
25062
World Ranking
16099
National Ranking
17

Overview

Manuel R. Teixeira is affiliated with the University of Porto in Portugal and has an extensive research portfolio primarily in Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Genetics, Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, and Cancer Research.

The scientist's research focuses on topics such as:

  • Genetic factors in colorectal cancer
  • BRCA gene mutations in cancer
  • Cancer Genomics and Diagnostics
  • Prostate Cancer Treatment and Research
  • Genetic Associations and Epidemiology
  • DNA Repair Mechanisms
  • Molecular Biology Techniques and Applications

Frequent co-authors include Ana Peixoto, Catarina Santos, Carla Pinto, Rosalind A. Eeles, and Kenneth Muir, reflecting collaborative efforts across multiple projects.

Manuel R. Teixeira's research outputs have appeared in a variety of publication venues, including:

  • Cancers
  • Nature Communications
  • European Journal of Human Genetics
  • Scientific Reports
  • GE Portuguese Journal of Gastroenterology

Significant recent papers demonstrate a focus on cancer-related genomics and clinical implications. Notable examples include:

  • An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk (2020, Nature Communications)
  • Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome (2020, European Journal of Human Genetics)
  • A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study (2021, The Lancet Oncology)
  • Hereditary Predisposition to Prostate Cancer: From Genetics to Clinical Implications (2020, International Journal of Molecular Sciences)
  • Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan (2020, Nature Communications)

Their scientific contributions primarily address complex mechanisms underlying cancer susceptibility and progression, particularly in prostate cancer and hereditary cancer syndromes. This is supported by the strong emphasis on DNA repair mechanisms and cancer genomics found in their publications.

Best Publications

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

    Rosalind A. Eeles;Ali Amin Al Olama;Sara Benlloch;Edward J. Saunders

  • The MLL recombinome of acute leukemias in 2013

    C. Meyer;J. Hofmann;T. Burmeister;D. Gröger

  • A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

    Ali Amin Al Olama;Zsofia Kote-Jarai;Sonja I. Berndt;David V. Conti

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    Haoyu Zhang;Haoyu Zhang;Thomas U. Ahearn;Julie Lecarpentier;Daniel Barnes

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • SMARCB1/INI1 Tumor Suppressor Gene Is Frequently Inactivated in Epithelioid Sarcomas

    Piergiorgio Modena;Elena Lualdi;Federica Facchinetti;Lisa Galli

  • A quantitative promoter methylation profile of prostate cancer.

    Carmen Jerónimo;Rui Henrique;Rui Henrique;Mohammad O. Hoque;Elizabeth Mambo

  • Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers

    Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Lesley McGuffog;Daniel Barrowdale;Andrew Lee

  • TMPRSS2-ERG Gene Fusion Causing ERG Overexpression Precedes Chromosome Copy Number Changes in Prostate Carcinomas and Paired HGPIN Lesions

    Nuno Cerveira;Franclim R. Ribeiro;Ana Peixoto;Vera Costa

  • Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

    Yilong Li;Claire Schwab;Sarra L. Ryan;Elli Papaemmanuil

  • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

    Timothy R. Rebbeck;Tara M. Friebel;Eitan Friedman;Ute Hamann

  • Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study

    Elizabeth K. Bancroft;Elizabeth C. Page;Elena Castro;Hans Lilja

  • An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk.

    Lang Wu;Yaohua Yang;Xingyi Guo;Xiao Ou Shu

  • Association of ERBB2 gene status with histopathological parameters and disease-specific survival in gastric carcinoma patients

    J D Barros-Silva;D Leitão;L Afonso;J Vieira

  • Guidelines for the Li–Fraumeni and heritable TP53-related cancer syndromes

    Thierry Frebourg;Svetlana Bajalica Lagercrantz;Carla Oliveira;Rita Magenheim

  • Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci.

    Marianne Berg;Marianne Berg;Trude H. Ågesen;Trude H. Ågesen;Espen Thiis-Evensen;Marianne A. Merok

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Kenneth W. Muir
Kenneth W. Muir University of Manchester
Johanna Schleutker
Johanna Schleutker Turku University Hospital
David E. Neal
David E. Neal University of Cambridge
Lisa A. Cannon-Albright
Lisa A. Cannon-Albright University of Utah
Rui Henrique
Rui Henrique University of Porto
Rosalind A. Eeles
Rosalind A. Eeles Institute of Cancer Research
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Melissa C. Southey
Melissa C. Southey Monash University
Jyotsna Batra
Jyotsna Batra Queensland University of Technology

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