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Biology and Biochemistry

D-Index
47
Citations
10640
World Ranking
18610
National Ranking
7608

Overview

Shinya Shibutani is affiliated with Stony Brook University in the United States. Their research contributions span the fields of medicine, biochemistry, genetics, and molecular biology. The main areas of study focus on genetics, endocrinology, diabetes and metabolism, as well as oncology.

The scientific topics addressed in Shibutani's work include:

  • Estrogen and related hormone effects
  • Menopause: Health Impacts and Treatments
  • Cancer Risks and Factors

Shibutani has published research in the International Journal of Molecular Sciences. One notable paper is titled "Less Carcinogenic Chlorinated Estrogens Applicable to Hormone Replacement Therapy", published in 2021 in the same journal.

Collaboration with other researchers is a component of Shibutani's scholarly work. Frequent co-authors include:

  • Yoshinori Okamoto
  • Hideto Jinno
  • Shinji Itoh

The primary disciplines of Shibutani's publications demonstrate an interdisciplinary approach, combining molecular biology and clinical medicine to address questions related to hormone replacement therapies and cancer risks.

Best Publications

  • Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG.

    Shinya Shibutani;Masaru Takeshita;Arthur P. Grollman

  • 8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

    J Tchou;H Kasai;S Shibutani;M H Chung

  • Aristolochic acid and the etiology of endemic (Balkan) nephropathy

    Arthur P. Grollman;Shinya Shibutani;Masaaki Moriya;Frederick Miller

  • Substrate specificity of Fpg protein. Recognition and cleavage of oxidatively damaged DNA.

    J Tchou;V Bodepudi;S Shibutani;I Antoshechkin

  • NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).cntdot.dA(anti) alignment at lesion site

    Michael Kouchakdjian;Veeraiah Bodepudi;Shinya Shibutani;Moises Eisenberg

  • Translesional synthesis on DNA templates containing a single abasic site. A mechanistic study of the "A rule"

    Shinya Shibutani;Masaru Takeshita;Arthur P. Grollman

  • Translesion Synthesis by Human DNA Polymerase κ on a DNA Template Containing a Single Stereoisomer of dG-(+)- or dG-(−)-anti-N2-BPDE (7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene)†

    Naomi Suzuki;Eiji Ohashi;Alexander Kolbanovskiy;Nicholas E. Geacintov

  • Increased DNA damage in ALDH2-deficient alcoholics.

    Tomonari Matsuda;Hisatoshi Yabushita;Robert A Kanaly;Shinya Shibutani

  • Selective toxicity of aristolochic acids I and II.

    Shinya Shibutani;Huan Dong;Naomi Suzuki;Shiro Ueda

  • Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage.

    Kevin G. Pinz;Shinya Shibutani;Daniel F. Bogenhagen

  • On the mechanism of frameshift (deletion) mutagenesis in vitro.

    Shinya Shibutani;A. P. Grollman

  • Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2′-deoxyadenosine and 8-oxo-7,8-dihydro-2′-deoxyguanosine DNA lesions in mammalian cells

    Xingzhi Tan;Arthur P. Grollman;Shinya Shibutani

  • Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen.

    Shinya Shibutani;Anisetti Ravindernath;Naomi Suzuki;Isamu Terashima

  • Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase δ

    Dmitry Ju. Mozzherin;Shinya Shibutani;Cheng-Keat Tan;Kathleen M. Downey

  • α-Hydroxytamoxifen Is a Substrate of Hydroxysteroid (Alcohol) Sulfotransferase, Resulting in Tamoxifen DNA Adducts

    Shinya Shibutani;Lakkaraju Dasaradhi;Isamu Terashima;Erden Banoglu

  • Sulfation of alpha-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts.

    S Shibutani;P M Shaw;N Suzuki;L Dasaradhi

  • Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7, 8-dihydroxy-anti-9, 10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

    Shinya Shibutani;Leonid A. Margulis;Nicholas E. Geacintov;Arthur P. Grollman

  • Tamoxifen-DNA adducts detected in the endometrium of women treated with tamoxifen.

    Shinya Shibutani;Naomi Suzuki;Isamu Terashima;Steven M. Sugarman

  • Effective Utilization of N2-Ethyl-2‘-deoxyguanosine Triphosphate during DNA Synthesis Catalyzed by Mammalian Replicative DNA Polymerases†

    Tomonari Matsuda;Isamu Terashima;Yoshihiro Matsumoto;Hisatoshi Yabushita

  • Identification of tamoxifen-DNA adducts formed by alpha-sulfate tamoxifen and alpha-acetoxytamoxifen.

    Lakkaraju Dasaradhi;Shinya Shibutani

Frequent Co-Authors

Arthur P. Grollman
Arthur P. Grollman Stony Brook University
Francis Johnson
Francis Johnson Stony Brook University
Fumio Hanaoka
Fumio Hanaoka National Institute of Genetics
Nicholas E. Geacintov
Nicholas E. Geacintov New York University
Frederick W. Miller
Frederick W. Miller National Institutes of Health
Toshio Mori
Toshio Mori Nara Medical University
Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Miriam C. Poirier
Miriam C. Poirier National Institutes of Health
Aziz Sancar
Aziz Sancar University of North Carolina at Chapel Hill

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