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Biology and Biochemistry

D-Index
46
Citations
6626
World Ranking
18994
National Ranking
31

Overview

Vilím Šimánek was affiliated with Palacký University, Olomouc in the Czech Republic. Their research contributions primarily focused on medicine and neuroscience, with additional work in pharmacology, endocrine and autonomic systems, molecular biology, toxicology, and pharmacy.

The scientific work of Vilím Šimánek addressed multiple topics, including:

  • Cannabis and Cannabinoid Research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Forensic Toxicology and Drug Analysis
  • Infant Health and Development
  • Neuroscience of respiration and sleep
  • Biochemical effects in animals
  • Free Radicals and Antioxidants

Among the recent published papers were:

  • Cannabidiol and periodontal inflammatory disease: A critical assessment, 2022, published in Biomedical Papers
  • Phytocannabinoids and gingival inflammation: Preclinical findings and a placebo-controlled double-blind randomized clinical trial with cannabidiol, 2024, published in Journal of Periodontal Research
  • Carnosine and β-alanine in aging. Their impact on skeletal muscle and neurodegenerative disorders, 2021, published in Medicína pro praxi

Vilím Šimánek frequently collaborated with coauthors including P Jirásek, A Jusku, Jana Franková, Jan Storch, and Jan Vacek. Their work was published in a variety of scientific venues, notably the Journal of Periodontal Research, Biomedical Papers, and Medicína pro praxi.

Best Publications

  • Antiinflammatory activity of quaternary benzophenanthridine alkaloids from Chelidonium majus.

    J. Lenfeld;M. Kroutil;E. Maršálek;J. Slavík

  • Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment

    Pavel Kosina;Daniela Walterová;Jitka Ulrichová;Václav Lichnovský

  • Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities

    Roman Zuber;Martin Modrianský;Zdeněk Dvořák;Petr Rohovský

  • Phytochemical and antimicrobial characterization of Macleaya cordata herb.

    Pavel Kosina;Jana Gregorova;Jiri Gruz;Jan Vacek

  • Silymarin Inhibits the Development of Diet-Induced Hypercholesterolemia in Rats

    V. Krečman;N. Škottová;D. Walterová;J. Ulrichová

  • Biosafety, Antioxidant Status, and Metabolites in Urine after Consumption of Dried Cranberry Juice in Healthy Women: A Pilot Double-Blind Placebo-Controlled Trial

    Kateřina Valentová;David Stejskal;Petr Bednář;Jitka Vostálová

  • Constituents and antimicrobial properties of blue honeysuckle: a novel source for phenolic antioxidants.

    Irena Palíková;Jan Heinrich;Petr Bednář;Petr Marhol

  • Antioxidant activity of extracts from the leaves of Smallanthus sonchifolius.

    Katerina Valentova;Ladislav Cvak;Alexandr Muck;Jitka Ulrichova

  • Are High Proanthocyanidins Key to Cranberry Efficacy in the Prevention of Recurrent Urinary Tract Infection

    Jitka Vostalova;Ales Vidlar;Vilim Simanek;Adela Galandakova

  • Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts.

    A Zdarilová;A Svobodová;V Simánek;J Ulrichová

  • Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Part III. Apigenin, baicalelin, kaempherol, luteolin and quercetin.

    Jitka Psotová;Šárka Chlopčíková;Petra Miketová;Jan Hrbáč

  • The in vitro biological activity of Lepidium meyenii extracts

    K Valentová;D Buckiová;V Kren;J Peknicová

  • Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum.

    Zdeněk Dvořák;Pavel Kosina;Daniela Walterová;Vilı́m Šimánek

  • Silymarin: What is in the name...? An appeal for a change of editorial policy.

    Vilím Šimánek;Vladimír Kren;Jitka Ulrichová;Jaroslav Vicar

  • The influence of maca (Lepidium meyenii) on antioxidant status, lipid and glucose metabolism in rat.

    Rostislav Vecera;Jan Orolin;Nina Skottová;Ludmila Kazdová

  • Effects of silymarin flavonolignans and synthetic silybin derivatives on estrogen and aryl hydrocarbon receptor activation

    Martina Plísková;Jan Vondrácek;Vladimír Kren;Radek Gazák

  • Chemoprotective effect of plant phenolics against anthracycline‐induced toxicity on rat cardiomyocytes Part II. caffeic, chlorogenic and rosmarinic acids

    Šárka Chlopčíková;Jitka Psotová;Petra Miketová;Jaromír Soušek

  • Cytotoxicity of natural compounds in hepatocyte cell culture models. The case of quaternary benzo[c]phenanthridine alkaloids.

    Jitka Ulrichová;Zdeněk Dvořák;Jaroslav Vičar;Jan Lata

  • Alkaloids and organic acids content of eight Fumaria species

    J. Soušek;D. Guédon;T. Adam;Hana Bochořáková

  • Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: in vivo safety assessment.

    Katerina Valentová;David Stejskal;Josef Bartek;Svatava Dvorácková

Frequent Co-Authors

Jitka Ulrichová
Jitka Ulrichová Palacký University, Olomouc
Vladimir Kren
Vladimir Kren Czech Academy of Sciences
Vladimír Křen
Vladimír Křen Czech Academy of Sciences
Marie Stiborová
Marie Stiborová Charles University
Michal Holčapek
Michal Holčapek University of Pardubice
Eva Frei
Eva Frei Charles University
Osao Adachi
Osao Adachi Yamaguchi University
Pavel Hobza
Pavel Hobza Czech Academy of Sciences
Miroslav Fojta
Miroslav Fojta Czech Academy of Sciences
Bořivoj Klejdus
Bořivoj Klejdus Mendel University Brno

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