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Takashi Ikejima

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
13642
World Ranking
9744
National Ranking
301

Takashi Ikejima publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Takashi Ikejima sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 262 publications — 70th percentile

70% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Takashi Ikejima D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Takashi Ikejima sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 64 D-Index — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Takashi Ikejima is affiliated with Shenyang Pharmaceutical University in China. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, with a substantial focus also on Medicine. Subfields of study include Molecular Biology, Pulmonary and Respiratory Medicine, Immunology, Cell Biology, and Physiology.

Their main research topics cover a variety of biological and biochemical mechanisms, specifically:

  • Silymarin and Mushroom Poisoning
  • Interferon and Immune Responses
  • Autophagy in Disease and Therapy
  • Heme Oxygenase-1 and Carbon Monoxide
  • Hippo pathway signaling and YAP/TAZ
  • Inflammasome and Immune Disorders
  • Calcium signaling and nucleotide metabolism

Takashi Ikejima has contributed to numerous research publications. Among the recent papers are:

  • "DNA damage-triggered activation of cGAS-STING pathway induces apoptosis in human keratinocyte HaCaT cells" (2021, Molecular Immunology)
  • "Silibinin ameliorates depression/anxiety-like behaviors of Parkinson's disease mouse model and is associated with attenuated STING-IRF3-IFN-β pathway activation and neuroinflammation" (2021, Physiology & Behavior)
  • "Silibinin inhibits ethanol- or acetaldehyde-induced ferroptosis in liver cell lines" (2022, Toxicology in Vitro)
  • "Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy" (2023, Archives of Biochemistry and Biophysics)
  • "Silibinin-induced mitochondria fission leads to mitophagy, which attenuates silibinin-induced apoptosis in MCF-7 and MDA-MB-231 cells" (2020, Archives of Biochemistry and Biophysics)

Frequent publication venues for Ikejima's work include:

  • Archives of Biochemistry and Biophysics
  • Molecular Immunology
  • Toxicology in Vitro
  • Connective Tissue Research
  • Cellular Signalling

Their collaborative work features co-authorship with several researchers, notably:

  • Shunji Hattori
  • Hitomi Fujisaki
  • Kazunori Mizuno
  • Toshihiko Hayashi
  • Weiwei Liu

Best Publications

  • Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

    S Okusawa;J A Gelfand;T Ikejima;R J Connolly

  • Interleukin 1 induces interleukin 1. I: Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro

    C. A. Dinarello;T. Ikejima;S. J. C. Warner;S. F. Orencole

  • Silibinin prevents amyloid β peptide-induced memory impairment and oxidative stress in mice

    P. Lu;P. Lu;T. Mamiya;L. L. Lu;L. L. Lu;Akihiro Mouri

  • Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro

    J. W.M. Van Der Meer;S. Endres;G. Lonnemann;Joseph Gerard Cannon

  • Induction of human interleukin-1 by a product of Staphylococcus aureus associated with toxic shock syndrome.

    T Ikejima;C A Dinarello;D M Gill;S M Wolff

  • Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits.

    T. Ikejima;S. Okusawa;P. Ghezzi;J.W.M. van der Meer

  • ERK and JNK mediate TNFα-induced p53 activation in apoptotic and autophagic L929 cell death

    Yan Cheng;Feng Qiu;Shin-ichi Tashiro;Satoshi Onodera

  • Autophagy preceded apoptosis in oridonin-treated human breast cancer MCF-7 cells.

    Qiao Cui;Shin-ichi Tashiro;Satoshi Onodera;Mutsuhiko Minami

  • Molecular Characterization and Diagnostic Value of Taenia solium Low-Molecular-Weight Antigen Genes

    Yasuhito Sako;Minoru Nakao;Takashi Ikejima;Xian Zhi Piao

  • Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways

    Ning Kang;Jing-Hai Zhang;Feng Qiu;Shin-ichi Tashiro

  • Reactive Oxygen Species Mediate Oridonin-Induced HepG2 Apoptosis Through p53, MAPK, and Mitochondrial Signaling Pathways

    Jian Huang;Lijun Wu;Shin-ichi Tashiro;Satoshi Onodera

  • Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells.

    Xiao Fang Fei;Ben Xiang Wang;Tei Jin Li;Shin-ichi Tashiro

  • p53-Mediated Cell Cycle Arrest and Apoptosis Induced by Shikonin via a Caspase-9-Dependent Mechanism in Human Malignant Melanoma A375-S2 Cells

    Zhen Wu;Lijun Wu;Linhao Li;Shin-ichi Tashiro

  • Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK, and P38 regulation.

    Qiao Cui;Shin-ichi Tashiro;Satoshi Onodera;Mutsuhiko Minami

  • P53-mediated cell cycle arrest and apoptosis through a caspase-3- independent, but caspase-9-dependent pathway in oridonin-treated MCF-7 human breast cancer cells.

    Qiao Cui;Jing-hua Yu;Jin-nan Wu;Shin-ichi Tashiro

  • Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells.

    Jia Yang;Li-Jun Wu;Shin-Ichi Tashino;Satoshi Onodera

  • Autophagy inhibits reactive oxygen species‐mediated apoptosis via activating p38‐nuclear factor‐kappa B survival pathways in oridonin‐treated murine fibrosarcoma L929 cells

    Yan Cheng;Feng Qiu;Yuan-Chao Ye;Zhao-Ming Guo

  • Crystallization behavior and environmental biodegradability of the blend films of poly(3-hydroxybutyric acid) with chitin and chitosan

    T Ikejima;Y Inoue

  • Induction by Toxic-Shock-Syndrome Toxin-1 of a Circulating Tumor Necrosis Factor-Like Substance in Rabbits and of Immunoreactive Tumor Necrosis Factor and Interleukin-1 from Human Mononuclear Cells

    T. Ikejima;S. Okusawa;J.W.M. van der Meer;C.A. Dinarello

  • Silibinin Protects Against Isoproterenol-Induced Rat Cardiac Myocyte Injury Through Mitochondrial Pathway After Up-regulation of SIRT1

    Bei Zhou;Li-Jun Wu;Lin-Hao Li;Shin-ichi Tashiro

Frequent Co-Authors

Satoshi Onodera
Satoshi Onodera Showa Pharmaceutical University
Shin-ichi Tashiro
Shin-ichi Tashiro Kyoto Prefectural University of Medicine
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Masayuki Yamato
Masayuki Yamato Tokyo Women's Medical University
Akira Ito
Akira Ito Asahikawa Medical University
Minoru Nakao
Minoru Nakao Asahikawa Medical University
Toshitaka Nabeshima
Toshitaka Nabeshima Meijo University
Haruki Yamada
Haruki Yamada Kitasato University
Taku Nagai
Taku Nagai Nagoya University
Marcello Otake Sato
Marcello Otake Sato Niigata University of Pharmacy and Applied Life Sciences

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Best Scientists Citing Takashi Ikejima

Charles A. Dinarello

Charles A. Dinarello

University of Colorado Anschutz Medical Campus

Publications: 148

Akira Ito

Akira Ito

Asahikawa Medical University

Publications: 69

Minoru Nakao

Minoru Nakao

Asahikawa Medical University

Publications: 34

Stefan Endres

Stefan Endres

Ludwig-Maximilians-Universität München

Publications: 25

Jos W. M. van der Meer

Jos W. M. van der Meer

Radboud University Medical Center

Publications: 23

Toni Wandra

Toni Wandra

Universitas Sari Mutiara Indonesia - (USM-Indonesia)

Publications: 21

Mihai G. Netea

Mihai G. Netea

Radboud University

Publications: 20

Munehiro Okamoto

Munehiro Okamoto

Kyoto University

Publications: 18

Marcello Otake Sato

Marcello Otake Sato

Niigata University of Pharmacy and Applied Life Sciences

Publications: 18

Leo A. B. Joosten

Leo A. B. Joosten

Radboud University

Publications: 17

Yitao Wang

Yitao Wang

University of Macau

Publications: 16

Jean-Marc Cavaillon

Jean-Marc Cavaillon

Institut Pasteur

Publications: 14

Jia Zhou

Jia Zhou

The University of Texas Medical Branch at Galveston

Publications: 13

Carl Grunfeld

Carl Grunfeld

University of California, San Francisco

Publications: 13

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Philip S. Craig

University of Salford

Publications: 13

Tetsuya Yanagida

Tetsuya Yanagida

Yamaguchi University

Publications: 12

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