Andrew D. Wells

Overview

Best Publications

• Drug repurposing: progress, challenges and recommendations

  Sudeep Pushpakom;Francesco Iorio;Patrick A Eyers;K Jane Escott

  3546
  Citations

• Deacetylase inhibition promotes the generation and function of regulatory T cells

  Ran Tao;Edwin F de Zoeten;Engin Özkaynak;Chunxia Chen

  1039
  Citations

• Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

  Yongsheng Li;Xian Chang Li;Xin Xiao Zheng;Andrew D. Wells

  868
  Citations

• Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.

  Andrew D. Wells;Hrefna Gudmundsdottir;Laurence A. Turka

  726
  Citations

• Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

  Andrew D. Wells;Xian Chang Li;Yongsheng Li;Matthew C. Walsh

  718
  Citations

• Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.

  Marc O. Johnson;Marc O. Johnson;Melissa M. Wolf;Matthew Z. Madden;Gabriela Andrejeva

  665
  Citations

• Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question.

  Elliot J. Suchin;Peter B. Langmuir;Ed Palmer;Mohamed H. Sayegh

  663
  Citations

• Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression

  Valerie A Gerriets;Rigel J Kishton;Marc O Johnson;Marc O Johnson;Sivan Cohen

  536
  Citations

• Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor

  Iris Lee;Liqing Wang;Andrew D. Wells;Martin E. Dorf

  448
  Citations

• Dynamics and Requirements of T Cell Clonal Expansion In Vivo at the Single-Cell Level: Effector Function Is Linked to Proliferative Capacity

  Hrefna Gudmundsdottir;Andrew D. Wells;Laurence A. Turka

  341
  Citations

• The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo.

  Jianuo Liu;Takashi Miwa;Brendan Hilliard;Youhai Chen

  294
  Citations

• Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation.

  Chunxia Chen;Emily A. Rowell;Rajan M. Thomas;Wayne W. Hancock

  292
  Citations

• Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression

  Scott H. Adler;Elise Chiffoleau;Lanwei Xu;Nicole M. Dalton

  286
  Citations

• Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate

  Preston R. Arnold;Andrew D. Wells;Xian C. Li

  283
  Citations

• Epigenetic Remodeling of the IL-2 and IFN-γ Loci in Memory CD8 T Cells Is Influenced by CD4 T Cells

  John K. Northrop;Rajan M. Thomas;Andrew D. Wells;Andrew D. Wells;Hao Shen

  279
  Citations

• Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy.

  Andrew D. Wells;Matthew C. Walsh;Jeffrey A. Bluestone;Laurence A. Turka

  239
  Citations

• T cell death and transplantation tolerance.

  Xian Chang Li;Terry B. Strom;Laurence A. Turka;Andrew D. Wells

  236
  Citations

• Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view.

  Andrew D. Wells;Miroslav Malkovsky

  234
  Citations

• New Insights into the Molecular Basis of T Cell Anergy: Anergy Factors, Avoidance Sensors, and Epigenetic Imprinting

  Andrew D. Wells

  190
  Citations

• Signals from CD28 induce stable epigenetic modification of the IL-2 promoter.

  Rajan M. Thomas;Ling Gao;Andrew D. Wells;Andrew D. Wells

  173
  Citations