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James P. O'Gara

James P. O'Gara

D-Index & Metrics

Microbiology

D-Index
48
Citations
9535
World Ranking
4662
National Ranking
24

Overview

James P. O'Gara is affiliated with the National University of Ireland, Galway, where their research focuses on infectious diseases, molecular biology, and molecular medicine, particularly in the context of antimicrobial resistance and bacterial biofilms.

Their work spans several main fields of study, including:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader disciplines, their subfields of study include:

  • Infectious Diseases
  • Molecular Biology
  • Molecular Medicine
  • Microbiology
  • Rehabilitation

O'Gara's research centers around key topics such as:

  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Antibiotic Resistance in Bacteria
  • Antimicrobial Peptides and Activities
  • Wound Healing and Treatments
  • Antifungal resistance and susceptibility
  • Pressure Ulcer Prevention and Management

Their frequent co-authors include:

  • Merve S. Zeden
  • Georgina Gethin
  • Vinai C. Thomas
  • Aaron C. Nolan
  • Laura A. Gallagher

They have published extensively in several venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • PLoS Pathogens
  • International Journal of Nanomedicine
  • International Wound Journal

Recent papers by James P. O'Gara include:

  • Tailoring Nanoparticle-Biofilm Interactions to Increase the Efficacy of Antimicrobial Agents Against Staphylococcus aureus, 2020, International Journal of Nanomedicine
  • Enzyme-Functionalized Mesoporous Silica Nanoparticles to Target Staphylococcus aureus and Disperse Biofilms, 2021, International Journal of Nanomedicine
  • Purine Nucleosides Interfere with c-di-AMP Levels and Act as Adjuvants To Re-Sensitize MRSA To β-Lactam Antibiotics, 2022, mBio
  • Glycomics Microarrays Reveal Differential In Situ Presentation of the Biofilm Polysaccharide Poly-N-acetylglucosamine on Acinetobacter baumannii and Staphylococcus aureus Cell Surfaces, 2020, International Journal of Molecular Sciences
  • Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant Staphylococcus aureus (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics, 2021, mBio

Best Publications

  • ica and beyond: biofilm mechanisms and regulation in Staphylococcus epidermidis and Staphylococcus aureus

    James P. O'Gara

  • A Novel Staphylococcus aureus Biofilm Phenotype Mediated by the Fibronectin-Binding Proteins, FnBPA and FnBPB

    Eoghan O'Neill;Eoghan O'Neill;Clarissa Pozzi;Patrick Houston;Hilary Humphreys

  • Staphylococcus epidermidis biofilms: importance and implications.

    James P. O'gara;Hilary Humphreys

  • Association between Methicillin Susceptibility and Biofilm Regulation in Staphylococcus aureus Isolates from Device-Related Infections

    Eoghan O'Neill;Eoghan O'Neill;Clarissa Pozzi;Patrick Houston;Davida Smyth

  • Methicillin resistance and the biofilm phenotype in Staphylococcus aureus

    Hannah McCarthy;Justine K. Rudkin;Nikki S. Black;Laura Gallagher

  • icaR Encodes a Transcriptional Repressor Involved in Environmental Regulation of ica Operon Expression and Biofilm Formation in Staphylococcus epidermidis

    Kevin M. Conlon;Hilary Humphreys;James P. O'Gara

  • Methicillin Resistance Alters the Biofilm Phenotype and Attenuates Virulence in Staphylococcus aureus Device-Associated Infections

    Clarissa Pozzi;Elaine M. Waters;Justine K. Rudkin;Carolyn R. Schaeffer

  • Essential Role for the Major Autolysin in the Fibronectin-Binding Protein-Mediated Staphylococcus aureus Biofilm Phenotype

    Patrick Houston;Sarah E. Rowe;Clarissa Pozzi;Elaine M. Waters

  • Evidence for icaADBC-Independent Biofilm Development Mechanism in Methicillin-Resistant Staphylococcus aureus Clinical Isolates

    Fidelma Fitzpatrick;Hilary Humphreys;James P. O'Gara

  • Role of Surface Protein SasG in Biofilm Formation by Staphylococcus aureus

    Joan A. Geoghegan;Rebecca M. Corrigan;Dominika T. Gruszka;Pietro Speziale

  • The genetics of staphylococcal biofilm formation—will a greater understanding of pathogenesis lead to better management of device‐related infection?

    F. Fitzpatrick;H. Humphreys;H. Humphreys;J.P. O'Gara

  • Evaluation of Protein Adsorption on Atmospheric Plasma Deposited Coatings Exhibiting Superhydrophilic to Superhydrophobic Properties

    C. P. Stallard;K. A. McDonnell;O. D. Onayemi;J. P. O’Gara

  • Inactivations of rsbU and sarA by IS256 Represent Novel Mechanisms of Biofilm Phenotypic Variation in Staphylococcus epidermidis

    Kevin M. Conlon;Hilary Humphreys;James P. O'Gara

  • Convergence of Staphylococcus aureus Persister and Biofilm Research: Can Biofilms Be Defined as Communities of Adherent Persister Cells?

    Elaine M. Waters;Sarah E. Rowe;James P. O'Gara;Brian P. Conlon

  • Fibronectin-binding proteins are required for biofilm formation by community-associated methicillin-resistant Staphylococcus aureus strain LAC

    Jennifer McCourt;Dara P. O'Halloran;Hannah McCarthy;James P. O'Gara

  • Control of Photosystem Formation in Rhodobacter sphaeroides

    Jill Zeilstra-Ryalls;Mark Gomelsky;Jesus M. Eraso;Alexei Yeliseev

  • Methicillin Resistance Reduces the Virulence of Healthcare-Associated Methicillin-Resistant Staphylococcus aureus by Interfering With the agr Quorum Sensing System

    Justine K. Rudkin;Andrew M. Edwards;Maria G. Bowden;Eric L. Brown

  • Anti-biofilm activity of sub-inhibitory povidone-iodine concentrations against Staphylococcus epidermidis and Staphylococcus aureus.

    Kayode O. Oduwole;Aaron A. Glynn;Diarmuid C. Molony;David Murray

  • Untangling the Diverse and Redundant Mechanisms of Staphylococcus aureus Biofilm Formation.

    Marta Zapotoczna;Eoghan O’Neill;Eoghan O’Neill;James P. O'Gara

  • A Staphylococcal GGDEF Domain Protein Regulates Biofilm Formation Independently of Cyclic Dimeric GMP

    Linda M. Holland;Sinéad T. O'Donnell;Dmitri A. Ryjenkov;Larissa Gomelsky

Frequent Co-Authors

Hilary Humphreys
Hilary Humphreys Royal College of Surgeons in Ireland
Paul D. Fey
Paul D. Fey University of Nebraska Medical Center
Felipe Cava
Felipe Cava Umeå University
Aras Kadioglu
Aras Kadioglu University of Liverpool
Catherine M. Greene
Catherine M. Greene Royal College of Surgeons in Ireland
Joan A. Geoghegan
Joan A. Geoghegan University of Birmingham
Timothy J. Foster
Timothy J. Foster Campden BRI (United Kingdom)
Alex J. O'Neill
Alex J. O'Neill University of Leeds
Mark Gomelsky
Mark Gomelsky University of Wyoming
Samuel Kaplan
Samuel Kaplan The University of Texas Health Science Center at Houston

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