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Pietro Speziale

Pietro Speziale

D-Index & Metrics

Microbiology

D-Index
63
Citations
13430
World Ranking
2750
National Ranking
66

Overview

Pietro Speziale is affiliated with the University of Pavia in Italy. Their research focuses primarily on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, their work spans several subfields including Molecular Biology, Infectious Diseases, Atomic and Molecular Physics, and Optics, Immunology, and Public Health, Environmental and Occupational Health.

The main topics covered by Speziale's research include:

  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Biochemical and Structural Characterization
  • Force Microscopy Techniques and Applications
  • Streptococcal Infections and Treatments
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Antimicrobial Peptides and Activities

Their recent publications illustrate a focus on bacterial pathogenesis, host-pathogen interactions, and the molecular mechanisms underlying infections caused by Staphylococcus aureus. Notable recent papers include:

  • "The Multivalent Role of Fibronectin-Binding Proteins A and B (FnBPA and FnBPB) of Staphylococcus aureus in Host Infections" (2020, Frontiers in Microbiology)
  • "Staphylococcus aureus induces neutrophil extracellular traps (NETs) and neutralizes their bactericidal potential" (2021, Computational and Structural Biotechnology Journal)

Speziale has also contributed to interdisciplinary articles in collaboration with other researchers. Frequent co-authors in their work include Giampiero Pietrocola, Yves F. Dufrêne, Marion Mathelié-Guinlet, Felipe Viela, and Chiara Motta.

Publication venues where Speziale's work appears repeatedly include:

  • Nano Letters
  • International Journal of Molecular Sciences
  • Computational and Structural Biotechnology Journal
  • Scientific Reports
  • Research Square

The research involves a range of experimental techniques and focuses on elucidating molecular mechanisms involved in bacterial adhesion, immune evasion, and infection persistence, often emphasizing Staphylococcus aureus. The integration of biophysical methods such as force microscopy is also evident in their contributions, enhancing understanding of pathogen-host interactions at the molecular level.

Best Publications

  • Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials.

    Carla Renata Arciola;Davide Campoccia;Pietro Speziale;Lucio Montanaro

  • Antibiotic-loaded biomaterials and the risks for the spread of antibiotic resistance following their prophylactic and therapeutic clinical use.

    Davide Campoccia;Lucio Montanaro;Pietro Speziale;Carla Renata Arciola

  • Scenery of Staphylococcus implant infections in orthopedics

    Lucio Montanaro;Pietro Speziale;Davide Campoccia;Stefano Ravaioli

  • Role of fibronectin-binding MSCRAMMs in bacterial adherence and entry into mammalian cells.

    Danny Joh;Elisabeth R. Wann;Bernd Kreikemeyer;Pietro Speziale

  • Extracellular DNA in biofilms.

    Lucio Montanaro;Alessandro Poggi;Livia Visai;Stefano Ravaioli

  • Protein-based biofilm matrices in Staphylococci.

    Pietro Speziale;Giampiero Pietrocola;Timothy J. Foster;Joan A. Geoghegan

  • A collagen receptor on Staphylococcus aureus strains isolated from patients with septic arthritis mediates adhesion to cartilage

    Lech M. Switalski;Joseph M. Patti;Wade Butcher;Anthony G. Gristina

  • Characterization of novel LPXTG-containing proteins of Staphylococcus aureus identified from genome sequences.

    Fiona M. Roche;Ruth Massey;Sharon J. Peacock;Nicholas P. J. Day

  • Role of Surface Protein SasG in Biofilm Formation by Staphylococcus aureus

    Joan A. Geoghegan;Rebecca M. Corrigan;Dominika T. Gruszka;Pietro Speziale

  • The serine-aspartate repeat (Sdr) protein family in Staphylococcus epidermidis.

    Kirk W. McCrea;Orla Hartford;Stacey Davis;Deirdre Nı́ Eidhin

  • The collagen-binding protein of Streptococcus mutans is involved in haemorrhagic stroke

    Kazuhiko Nakano;Kazuya Hokamura;Naho Taniguchi;Koichiro Wada

  • Isolation and characterization of a fibronectin receptor from Staphylococcus aureus.

    G Fröman;Lm Switalski;Pietro Speziale;M. Höök

  • Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model.

    Adam C. Schaffer;Robert M. Solinga;Jordan Cocchiaro;Marta Portoles

  • Toluidine Blue-Mediated Photodynamic Effects on Staphylococcal Biofilms

    Mrinalini Sharma;Livia Visai;Francesca Bragheri;Ilaria Cristiani

  • Identification and preliminary characterization of cell-wall-anchored proteins of Staphylococcus epidermidis

    M. Gabriela Bowden;Wei Chen;Jenny Singvall;Yi Xu

  • Fibronectin receptors from Staphylococcus aureus.

    C. Ryden;K. Rubin;P. Speziale;Magnus Hook

  • The Sbi Protein Is a Multifunctional Immune Evasion Factor of Staphylococcus aureus

    Emma Jane Smith;Livia Visai;Steven W. Kerrigan;Pietro Speziale

  • The effect of photodynamic treatment combined with antibiotic action or host defence mechanisms on Staphylococcus aureus biofilms

    Antonella Di Poto;Maria S. Sbarra;Giulio Provenza;Livia Visai

  • Fibronectin-binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FcγRIIa receptor

    J. Ross Fitzgerald;Anthony Loughman;Fiona Keane;Marian Brennan

  • Antibiotic resistance in exopolysaccharide-forming Staphylococcus epidermidis clinical isolates from orthopaedic implant infections

    Carla Renata Arciola;Davide Campoccia;Simonetta Gamberini;Maria Elena Donati

Frequent Co-Authors

Livia Visai
Livia Visai University of Pavia
Timothy J. Foster
Timothy J. Foster Campden BRI (United Kingdom)
Carla Renata Arciola
Carla Renata Arciola University of Bologna
Lucio Montanaro
Lucio Montanaro University of Bologna
Magnus Höök
Magnus Höök Texas A&M Health Science Center
Joan A. Geoghegan
Joan A. Geoghegan University of Birmingham
Yves F. Dufrêne
Yves F. Dufrêne Université Catholique de Louvain
Maria Cristina Tanzi
Maria Cristina Tanzi Polytechnic University of Milan
Antonio Toniolo
Antonio Toniolo University of Insubria
Silvia Farè
Silvia Farè Polytechnic University of Milan

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