World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
64
Citations
13793
World Ranking
8091
National Ranking
1423

Overview

Wenhao Hu is affiliated with Sun Yat-sen University in China and has a research focus primarily in the field of Chemistry, with notable contributions across several subfields including Organic Chemistry, Materials Chemistry, Molecular Biology, Oncology, and Electrical and Electronic Engineering.

Their work spans a range of topics related to chemical synthesis and reaction mechanisms. Key topics associated with their research include:

  • Cyclopropane Reaction Mechanisms
  • Catalytic C-H Functionalization Methods
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Catalytic Alkyne Reactions
  • Synthesis and Catalytic Reactions
  • Synthetic Organic Chemistry Methods

Wenhao Hu has published extensively in various scientific venues. The most frequent publication platforms include:

  • The Cambridge Structural Database
  • Organic Letters
  • arXiv (Cornell University)
  • SSRN Electronic Journal
  • Organic & Biomolecular Chemistry

Their recent papers demonstrate a range of interdisciplinary research topics and techniques. Notable recent publications include:

  • Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001), 2023, Signal Transduction and Targeted Therapy
  • A novel STAT3 inhibitor W2014-S regresses human non-small cell lung cancer xenografts and sensitizes EGFR-TKI acquired resistance, 2020, Theranostics
  • Ternary Catalysis Enabled Three-Component Asymmetric Allylic Alkylation as a Concise Track to Chiral α,α-Disubstituted Ketones, 2021, Journal of the American Chemical Society
  • Enantioselective three-component aminomethylation of α-diazo ketones with alcohols and 1,3,5-triazines, 2020, Nature Communications
  • Enantioselective Oxidative Multi-Functionalization of Terminal Alkynes with Nitrones and Alcohols for Expeditious Assembly of Chiral α-Alkoxy-β-amino-ketones, 2021, Journal of the American Chemical Society

Their collaborative network includes frequent coauthors such as Xinfang Xu, Yu Qian, Taoda Shi, Kemiao Hong, and Huang Qiu, reflecting a multidisciplinary approach to scientific inquiry.

Best Publications

  • Novel multicomponent reactions via trapping of protic onium ylides with electrophiles.

    Xin Guo;Wenhao Hu

  • Cooperative catalysis with chiral Brønsted acid-Rh2(OAc)4: highly enantioselective three-component reactions of diazo compounds with alcohols and imines.

    Wenhao Hu;Xinfang Xu;Jing Zhou;Wei-Jun Liu

  • Highly enantioselective trapping of zwitterionic intermediates by imines

    Huang Qiu;Ming Li;Li Qin Jiang;Feng Ping Lv

  • Diastereoselectively Switchable Enantioselective Trapping of Carbamate Ammonium Ylides with Imines

    Jun Jiang;Hua-Dong Xu;Jian-Bei Xi;Bai-Yan Ren

  • Novel Spiro Phosphinite Ligands and Their Application in Homogeneous Catalytic Hydrogenation Reactions

    Albert S. C. Chan;Wenhao Hu;and Cheng-Chao Pai;Chak-Po Lau

  • Highly Effective Soluble Polymer-Supported Catalysts for Asymmetric Hydrogenation

    Qing-hua Fan;Chang-yu Ren;Chi-hung Yeung;Wen-hao Hu

  • Catalytic Asymmetric Functionalization of Aromatic CH Bonds by Electrophilic Trapping of Metal‐Carbene‐Induced Zwitterionic Intermediates

    Shikun Jia;Dong Xing;Dan Zhang;Wenhao Hu

  • Asymmetric Multicomponent Reactions Based on Trapping of Active Intermediates

    Dan Zhang;Wenhao Hu

  • Dirhodium(II) tetrakis[methyl 2-oxaazetidine-4-carboxylate]: a chiral dirhodium(II) carboxamidate of exceptional reactivity and selectivity.

    Michael P. Doyle;Simon B. Davies;Wenhao Hu

  • Epoxides and aziridines from diazoacetates via ylide intermediates.

    Michael P. Doyle;Wenhao Hu;Daren J. Timmons

  • Design, Synthesis, and Structure–Activity Relationship Studies of Novel Fused Heterocycles-Linked Triazoles with Good Activity and Water Solubility

    Xufeng Cao;Zhaoshuan Sun;Yongbing Cao;Ruilian Wang

  • Cooperative Catalysis in Multicomponent Reactions: Highly Enantioselective Synthesis of γ‐Hydroxyketones with a Quaternary Carbon Stereocenter

    Xiao-Yu Guan;Li-Ping Yang;Wenhao Hu

  • Enantioselective Palladium(II) Phosphate Catalyzed Three‐Component Reactions of Pyrrole, Diazoesters, and Imines

    Dan Zhang;Huang Qiu;Liqin Jiang;Fengping Lv

  • Highly selective catalyst-directed pathways to dihydropyrroles from vinyldiazoacetates and imines.

    Michael P. Doyle;Ming Yan;Wenhao Hu;Luisa S. Gronenberg

  • DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 2: C-terminal benzimidazoles and derivatives.

    Roland W. Bürli;Peter Jones;Dustin McMinn;Quan Le

  • Three-Component Reaction of Aryl Diazoacetates, Alcohols, and Aldehydes (or Imines): Evidence of Alcoholic Oxonium Ylide Intermediates

    Chong-Dao Lu;Hui Liu;Zhi-Yong Chen;Wen-Hao Hu

  • Efficient Trapping of Oxonium Ylides with Imines: A Highly Diastereoselective Three-Component Reaction for the Synthesis of β-Amino-α-hydroxyesters with Quaternary Stereocenters

    Haoxi Huang;Xin Guo;Xin Guo;Wenhao Hu;Wenhao Hu

  • A new class of chiral lewis acid catalysts for highly enantioselective hetero-Diels-Alder reactions: exceptionally high turnover numbers from dirhodium(II) carboxamidates.

    Michael P. Doyle;Iain M. Phillips;Wenhao Hu

  • Asymmetric Counter-Anion-Directed Aminomethylation: Synthesis of Chiral β-Amino Acids via Trapping of an Enol Intermediate.

    Zhenghui Kang;Zhenghui Kang;Yongheng Wang;Dan Zhang;Ruibo Wu

  • Bond cleavage, fragment modification and reassembly in enantioselective three-component reactions

    Dan Zhang;Jun Zhou;Fei Xia;Zhenghui Kang

  • A novel three-component reaction catalyzed by dirhodium(II) acetate: decomposition of phenyldiazoacetate with arylamine and imine for highly diastereoselective synthesis of 1,2-diamines.

    Yuanhua Wang;Yanxin Zhu;Zhiyong Chen;Aiqiao Mi

  • Selectivity control in enantioselective four-component reactions of aryl diazoacetates with alcohols, aldehydes and amines: an efficient approach to synthesizing chiral β-amino-α-hydroxyesters

    Xinfang Xu;Jing Zhou;Liping Yang;Wenhao Hu

  • An ylide transformation of rhodium(I) carbene: enantioselective three-component reaction through trapping of rhodium(I)-associated ammonium ylides by β-nitroacrylates.

    Xiaochu Ma;Jun Jiang;Siying Lv;Wenfeng Yao

Frequent Co-Authors

Michael P. Doyle
Michael P. Doyle The University of Texas at San Antonio
Albert S. C. Chan
Albert S. C. Chan Sun Yat-sen University
Peter Y. Zavalij
Peter Y. Zavalij University of Maryland, College Park
Eldon E. Baird
Eldon E. Baird California Institute of Technology
Jingen Deng
Jingen Deng Sichuan University
Do-Hyun Nam
Do-Hyun Nam Samsung Medical Center
Peter G. Jones
Peter G. Jones Technische Universität Braunschweig
Ichiro Nakano
Ichiro Nakano University of Alabama at Birmingham
Xiaoming Feng
Xiaoming Feng Sichuan University
Weiping Tang
Weiping Tang University of Wisconsin–Madison

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