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Eminy H. Y. Lee

Eminy H. Y. Lee

D-Index & Metrics

Neuroscience

D-Index
42
Citations
5199
World Ranking
7729
National Ranking
20

Overview

Eminy H. Y. Lee is a researcher affiliated with Academia Sinica in Taiwan, focusing primarily on the field of Biochemistry, Genetics and Molecular Biology. Their research encompasses subfields such as Molecular Biology, Genetics, Cognitive Neuroscience, Cell Biology, and Cellular and Molecular Neuroscience.

The scientist's body of work covers diverse topics, with significant emphasis on Genetics and Neurodevelopmental Disorders, Ubiquitin and proteasome pathways, and Autism Spectrum Disorder Research. Other areas of study include Epigenetics and DNA Methylation, Endoplasmic Reticulum Stress and Disease, Cancer-related gene regulation, and Signaling Pathways in Disease.

Notable recent publications by Eminy H. Y. Lee include the following:

  • Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome, 2020, Scientific Reports
  • Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation, 2020, Molecular Therapy
  • Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN, 2023, PLoS ONE
  • Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2, 2024, Cellular and Molecular Life Sciences
  • APP SUMOylation prevents BACE1 cleavage of APP and increases BACE1 degradation to promote the nonamyloidogenic pathway, 2025, Molecular Medicine

The frequent co-authors collaborating with Eminy H. Y. Lee include:

  • Yun-Li Ma
  • Yen-Chen Liu
  • Wei-Lun Hsu
  • Kuang-Min Cheng

The scientific articles appear in a range of publication venues such as:

  • Scientific Reports
  • Molecular Therapy
  • PLoS ONE
  • Cellular and Molecular Life Sciences
  • Molecular Medicine

Best Publications

  • Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats.

    Y.L Ma;H.L Wang;H.C Wu;C.L Wei

  • Intra-amygdala injections of corticotropin releasing factor facilitate inhibitory avoidance learning and reduce exploratory behavior in rats

    K. C. Liang;Eminy H. Y. Lee

  • The mesolimbic dopaminergic pathway is more resistant than the nigrostriatal dopaminergic pathway to MPTP and MPP+ toxicity: role of BDNF gene expression

    Hui-Chuan Hung;Eminy H.Y. Lee

  • sgk, a primary glucocorticoid-induced gene, facilitates memory consolidation of spatial learning in rats.

    Kuen J. Tsai;Shau K. Chen;Yun L. Ma;Wei L. Hsu

  • Corticotrophin-releasing factor produces a long-lasting enhancement of synaptic efficacy in the hippocampus

    H. L. Wang;M. J. Wayner;M. J. Wayner;C. Y. Chai;E. H. Y. Lee

  • MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways.

    Hui-Chuan Hung;Eminy H.Y Lee

  • Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease.

    Chih-Chieh Tao;Chih-Chieh Tao;Kuang-Min Cheng;Yun-Li Ma;Wei-Lun Hsu

  • Enhanced glial cell line-derived neurotrophic factor mRNA expression upon (−)-deprenyl and melatonin treatments

    Yu Ping Tang;Yun Li Ma;Chih Chang Chao;Kai Yi Chen

  • Enrichment enhances the expression of sgk, a glucocorticoid-induced gene, and facilitates spatial learning through glutamate AMPA receptor mediation.

    Eminy H. Y. Lee;W. L. Hsu;Y. L. Ma;P. J. Lee

  • Hippocampal CRF, NE, and NMDA system interactions in memory processing in the rat.

    E. H. Y. Lee;C. P. Lee;H. I. Wang;W. R. Lin

  • SGK1 Phosphorylation of IκB Kinase α and p300 Up-regulates NF-κB Activity and Increases N-Methyl-D-aspartate Receptor NR2A and NR2B Expression

    Derek J.C. Tai;Chia-Chen Su;Yun-Li Ma;Eminy H.Y. Lee

  • Neuroprotective mechanism of glial cell line-derived neurotrophic factor on dopamine neurons: role of antioxidation.

    C.C. Chao;Eminy H.Y. Lee

  • Integrin αv and NCAM mediate the effects of GDNF on DA neuron survival, outgrowth, DA turnover and motor activity in rats

    Chih Chang Chao;Yun Li Ma;Kuan Yu Chu;Eminy H.Y Lee

  • Role of lateral habenula in the regulation of exploratory behavior and its relationship to stress in rats

    Eminy H.Y. Lee;S.L. Huang

  • Expression of Integrin-Associated Protein Gene Associated with Memory Formation in Rats

    A-Min Huang;Hai Long Wang;Yu Ping Tang;Eminy H. Y. Lee

  • Role of hippocampal nitric oxide in memory retention in rats.

    A-Min Huang;Eminy H.Y. Lee

  • Corticotropin-releasing factor produces a protein synthesis--dependent long-lasting potentiation in dentate gyrus neurons.

    Hai L. Wang;Li Y. Tsai;Eminy H. Y. Lee

  • Impaired Memory Retention and Decreased Long-Term Potentiation in Integrin-Associated Protein-Deficient Mice

    Hui P. Chang;Frederik P. Lindberg;Hai L. Wang;A.M. Huang

  • SUMO modification of Akt regulates global SUMOylation and substrate SUMOylation specificity through Akt phosphorylation of Ubc9 and SUMO1.

    C H Lin;S Y Liu;E H Y Lee

  • Protein synthesis in the hippocampus associated with memory facilitation by corticotropin-releasing factor in rats

    E.H.Y. Lee;H.C. Hung;K.T. Lu;W.H. Chen

  • Amphetamine enhances memory retention and facilitates norepinephrine release from the hippocampus in rats

    E.H.Y. Lee;Y.L. Ma

  • MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.

    Derek J. C. Tai;Yen C. Liu;Yen C. Liu;Wei L. Hsu;Yun L. Ma

Frequent Co-Authors

Mark A. Geyer
Mark A. Geyer University of California, San Diego
Keng-Chen Liang
Keng-Chen Liang National Taiwan University

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