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Genetics

D-Index
77
Citations
33497
World Ranking
1742
National Ranking
223

Research.com Recognitions

  • 2008 - Fellow of the Royal Society of Edinburgh

Overview

Ian J. Jackson is affiliated with the University of Edinburgh in the United Kingdom. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a particular focus on cellular and molecular mechanisms related to pigmentation, ocular development, and related disorders.

The scientist's publication record includes research in various notable venues such as bioRxiv (Cold Spring Harbor Laboratory), Disease Models & Mechanisms, Genetics in Medicine, Genes, and Pigment Cell & Melanoma Research. Key recent papers include:

  • "Dopachrome tautomerase variants in patients with oculocutaneous albinism," 2020, Genetics in Medicine
  • "Genetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice," 2021, Disease Models & Mechanisms
  • "The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification," 2020, PLoS Genetics
  • "A mouse model of brittle cornea syndrome caused by mutation in Zfp469," 2021, Disease Models & Mechanisms
  • "Dopachrome tautomerase variants in patients with oculocutaneous albinism," 2020, bioRxiv (Cold Spring Harbor Laboratory)

Jackson collaborates frequently with several coauthors, including Lisa McKie, Margaret Keighren, Erola Pairo-Castineira, Angèle Tingaud-Sequeira, and Vincent Michaud. These partnerships have contributed to a range of joint publications across their research interests.

Their work covers a range of topics within genetics and molecular biology, with substantial emphasis on understanding melanin and skin pigmentation, retinal development and disorders, and biochemical analysis and sensing techniques. Other notable areas include ocular disorders and treatments, corneal surgery and disorders, skin protection and aging, and glaucoma-related retinal conditions.

  • Melanin and skin pigmentation
  • Retinal Development and Disorders
  • Biochemical Analysis and Sensing Techniques
  • Ocular Disorders and Treatments
  • Corneal surgery and disorders
  • Skin Protection and Aging
  • Glaucoma and retinal disorders

Their research is situated mainly within the broader fields of biochemistry, genetics, and molecular biology, with relevant subfields including cell biology, molecular biology, nutrition and dietetics, genetics, and radiology, nuclear medicine, and imaging.

  • Cell Biology
  • Molecular Biology
  • Nutrition and Dietetics
  • Genetics
  • Radiology, Nuclear Medicine and Imaging

Ian J. Jackson has been recognized as a Fellow of the Royal Society of Edinburgh since 2008, reflecting their standing within the scientific community.

Best Publications

  • Initial sequencing and comparative analysis of the mouse genome.

    Robert H. Waterston;Kerstin Lindblad-Toh;Ewan Birney;Jane Rogers

  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

    Y. Okazaki;M. Furuno;T. Kasukawa;J. Adachi

  • Mouse genomic variation and its effect on phenotypes and gene regulation

    T M Keane;L Goodstadt;P Danecek;M A White

  • Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans.

    Paloma Valverde;Eugene Healy;Ian Jackson;Jonathan L. Rees

  • Dominant role of the niche in melanocyte stem-cell fate determination

    Emi K. Nishimura;Emi K. Nishimura;Siobhán A. Jordan;Hideo Oshima;Hideo Oshima;Hisahiro Yoshida

  • Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability

    Gaël G. McGill;Martin Horstmann;Hans R. Widlund;Jinyan Du

  • A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase.

    Katsuhiko Tsukamoto;Ian Jackson;Kazunori Urabe;Paul M Montague

  • TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor.

    Karen P Steel;Duncan R. Davidson;Ian Jackson

  • A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

    Michelle M Simon;Simon Greenaway;Jacqueline K White;Helmut Fuchs

  • Evidence for Variable Selective Pressures at MC1R

    Rosalind M. Harding;Eugene Healy;Amanda J. Ray;Nichola S. Ellis

  • A reappraisal of non-consensus mRNA splice sites.

    Jackson Ij

  • Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo

    Marina A.F. Mackenzie;Siobhán A. Jordan;Peter S. Budd;Ian J. Jackson

  • A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus.

    Ian J. Jackson;Doreen M. Chambers;Katsuhiko Tsukamoto;Neal G. Copeland

  • The melanocyte lineage in development and disease.

    Richard L. Mort;Ian J. Jackson;E. Elizabeth Patton

  • Molecular and developmental genetics of mouse coat color.

    Ian J. Jackson

  • The Asp84Glu Variant of the Melanocortin 1 Receptor (MC1R) is Associated with Melanoma

    Paloma Valverde;Eugene Healy;Stephen Sikkink;Faye Haldane

  • Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation

    Niamh Flanagan;Eugene Healy;Amanda Ray;Sion Philips

  • A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse

    Ian J. Jackson

  • Melanocortin 1 receptor variants in an Irish population

    Rachel Smith;Eugene Healy;Shazia Siddiqui;Niamh Flanagan

  • The retinal pigmented epithelium is required for development and maintenance of the mouse neural retina

    Sophie M. Raymond;Ian J. Jackson

Frequent Co-Authors

Eugene Healy
Eugene Healy University of Southampton
Jonathan L. Rees
Jonathan L. Rees University of Edinburgh
Martin S. Taylor
Martin S. Taylor Harvard University
Mark A. Birch-Machin
Mark A. Birch-Machin Newcastle University
Steve D.M. Brown
Steve D.M. Brown Medical Research Council
Raoul C.M. Hennekam
Raoul C.M. Hennekam University of Amsterdam
Karen P. Steel
Karen P. Steel King's College London
Gudrun E. Moore
Gudrun E. Moore University College London
Philip Stanier
Philip Stanier University College London
Roger D. Cox
Roger D. Cox Medical Research Council

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