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Biology and Biochemistry

D-Index
58
Citations
13049
World Ranking
13102
National Ranking
5586

Overview

M. Kathryn Liszewski is affiliated with Washington University in St. Louis in the United States. Their research spans multiple fields including Medicine and Immunology and Microbiology, with particular expertise in Immunology, Infectious Diseases, Neurology, Molecular Biology, and Ophthalmology as subfields of study.

The scientist's research primarily focuses on the complement system in diseases, with notable work in SARS-CoV-2 and COVID-19 research. Other main topics include cerebrovascular and carotid artery diseases, ocular diseases such as Behçet's syndrome, renal diseases and glomerulopathies, COVID-19 clinical research studies, and the long-term effects of COVID-19.

Several recent papers demonstrate the range of their research interests and contributions:

  • The complement system in COVID-19: friend and foe? (2020, JCI Insight)
  • Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections (2021, Current Opinion in Immunology)
  • Dengue and the Lectin Pathway of the Complement System (2021, Viruses)
  • Lesion evolution and neurodegeneration in RVCL-S (2020, Neurology)
  • Alternative pathway activation: Ever ancient and ever new (2022, Immunological Reviews)

Liszewski has collaborated frequently with several researchers, including:

  • John P. Atkinson
  • John Atkinson
  • Anuja Java
  • Andria L. Ford
  • Jonathan J. Miner

Their work has been published in diverse venues, reflecting interdisciplinary contributions. Key publication venues include:

  • JCI Insight
  • Current Opinion in Immunology
  • Viruses
  • Neurology
  • Immunological Reviews

The focus on the complement system connects to a range of disease mechanisms and infectious agents, as illustrated by publications on COVID-19, dengue virus, and neurodegenerative conditions related to vascular inflammation. This interdisciplinary approach encompasses molecular biology aspects alongside clinical research.

Overall, M. Kathryn Liszewski's research contributions address critical immunological pathways and their implications across various organ systems and disease states, documented through multiple peer-reviewed publications and collaborative efforts within the scientific community.

Best Publications

  • Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.

    Jessica Caprioli;Marina Noris;Simona Brioschi;Gaia Pianetti

  • Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster.

    M K Liszewski;T W Post;J P Atkinson

  • Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

    M. Kathryn Liszewski;Martin Kolev;Gaelle Le Friec;Marilyn Leung

  • Virulence differences between monkeypox virus isolates from West Africa and the Congo basin.

    Nanhai Chen;Guiyun Li;M. Kathryn Liszewski;John P. Atkinson

  • Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria

    Helena Källström;M. Kathryn Liszewski;John P. Atkinson;Ann‐Beth Jonsson

  • Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome

    Anna Richards;Elizabeth J Kemp;M Kathryn Liszewski;Judith A Goodship

  • C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy

    Anna Richards;Arn M J M Van Den Maagdenberg;Joanna C. Jen;David Kavanagh

  • Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus.

    N Okada;M K Liszewski;J P Atkinson;M Caparon

  • West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H.

    Kyung Min Chung;M. Kathryn Liszewski;Grant Nybakken;Alan E. Davis

  • The complement system in COVID-19: friend and foe?

    Anuja Java;Anthony J. Apicelli;M. Kathryn Liszewski;Ariella Coler-Reilly

  • Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort

    Jane E. Salmon;Cara Heuser;Michael Triebwasser;M. Kathryn Liszewski

  • Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins.

    D M Lublin;M K Liszewski;T W Post;M A Arce

  • Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.

    T W Post;M K Liszewski;E M Adams;I Tedja

  • CD46: expanding beyond complement regulation.

    Rebecca C. Riley-Vargas;Darcy B. Gill;Claudia Kemper;M. Kathryn Liszewski

  • Membrane cofactor protein (CD46) protects cells from complement-mediated attack by an intrinsic mechanism.

    T. J. Oglesby;C. J. Allen;M. K. Liszewski;D. J. G. White

  • Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus

    M. Manchester;M. K. Liszewski;J. P. Atkinson;M. B. A. Oldstone

  • CD46 Is a Cellular Receptor for All Species B Adenoviruses except Types 3 and 7

    Marko Marttila;David Persson;Dan Gustafsson;M. Kathryn Liszewski

  • Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome

    Celia J. Fang;Veronique Fremeaux-Bacchi;M. Kathryn Liszewski;Gaia Pianetti

  • Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells

    Maria L. Barilla-LaBarca;M. Kathryn Liszewski;John D. Lambris;Dennis Hourcade

  • New roles for the major human 3'-5' exonuclease TREX1 in human disease.

    David Kavanagh;Dirk Spitzer;Parul H Kothari;Aisha Shaikh

Frequent Co-Authors

John P. Atkinson
John P. Atkinson Washington University in St. Louis
David J. Kavanagh
David J. Kavanagh Queensland University of Technology
Timothy H.J. Goodship
Timothy H.J. Goodship Newcastle University
Claudia Kemper
Claudia Kemper National Institutes of Health
Steven L. Brody
Steven L. Brody Washington University in St. Louis
Paul N. Barlow
Paul N. Barlow University of Edinburgh
Marina Noris
Marina Noris Mario Negri Institute for Pharmacological Research
Judith A. Goodship
Judith A. Goodship Newcastle University

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