H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Chemistry D-index 41 Citations 19,283 60 World Ranking 12203 National Ranking 679

Research.com Recognitions

Awards & Achievements

2001 - Fellow of the Royal Society, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • DNA
  • Biochemistry

Andrew G. W. Leslie focuses on Stereochemistry, ATP synthase, ATP synthase alpha/beta subunits, ATPase and Protein structure. His Stereochemistry research incorporates themes from Inverse agonist, Adenosine, Adenosine receptor and Transmembrane domain. His studies in ATP synthase integrate themes in fields like Adenosine triphosphate and ATP synthase gamma subunit.

His ATP synthase gamma subunit research includes themes of Catalytic cycle, Protein secondary structure and Chemiosmosis. His ATPase research is multidisciplinary, relying on both Hydrolase and Crystallography. The various areas that Andrew G. W. Leslie examines in his Protein structure study include Molecular biology, C-terminus, Conserved sequence and Capsid.

His most cited work include:

  • Overview of the CCP4 suite and current developments. (8258 citations)
  • Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria. (2569 citations)
  • iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM (2062 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in ATPase, Biochemistry, ATP synthase, Stereochemistry and Protein structure. His work carried out in the field of ATPase brings together such families of science as Hydrolase, Catalytic cycle, Crystallography and Yeast. His work on Enzyme as part of general Biochemistry research is frequently linked to Trypanosoma brucei, thereby connecting diverse disciplines of science.

The ATP synthase study which covers ATP synthase alpha/beta subunits that intersects with Chemiosmosis. His studies deal with areas such as Beta, Catalysis, Binding site and Protein folding as well as Stereochemistry. As a member of one scientific family, Andrew G. W. Leslie mostly works in the field of Protein structure, focusing on Biophysics and, on occasion, G protein-coupled receptor and Transmembrane protein.

He most often published in these fields:

  • ATPase (48.04%)
  • Biochemistry (38.24%)
  • ATP synthase (31.37%)

What were the highlights of his more recent work (between 2012-2020)?

  • Biochemistry (38.24%)
  • ATPase (48.04%)
  • ATP synthase (31.37%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Biochemistry, ATPase, ATP synthase, Binding site and Biophysics. His work on Protein structure, Polymerase, Transferase and Nucleic acid as part of his general Biochemistry study is frequently connected to Trypanosoma brucei, thereby bridging the divide between different branches of science. In general ATPase, his work in V-ATPase and ATP synthase gamma subunit is often linked to Fusobacterium nucleatum and Photophosphorylation linking many areas of study.

Andrew G. W. Leslie interconnects Hydrolase, ATP hydrolysis and Paracoccus denitrificans in the investigation of issues within ATP synthase. His Binding site research focuses on G protein-coupled receptor and how it connects with Agonist and Ligand. His studies examine the connections between Biophysics and genetics, as well as such issues in Transmembrane domain, with regards to G protein.

Between 2012 and 2020, his most popular works were:

  • Structure of the adenosine A2A receptor bound to an engineered G protein (252 citations)
  • High-resolution structure determination by continuous-rotation data collection in MicroED (191 citations)
  • The 2.1 Å resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor. (117 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • DNA
  • Biochemistry

Biophysics, Binding site, Protein structure, Transmembrane domain and Biochemistry are his primary areas of study. Andrew G. W. Leslie combines subjects such as Adenosine A2A receptor, G protein-coupled receptor and G protein with his study of Binding site. His G protein research incorporates themes from Arrestin and C-terminus.

His study in Protein structure is interdisciplinary in nature, drawing from both ATP hydrolysis, ATPase, Agonist, Inhibitor protein and Intrinsically disordered proteins. His Transmembrane domain study often links to related topics such as Ligand. His studies in ATP synthase and Hydrolase are all subfields of Biochemistry research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Overview of the CCP4 suite and current developments.

Martyn D. Winn;Charles C. Ballard;Kevin D Cowtan;Eleanor J. Dodson.
Acta Crystallographica Section D-biological Crystallography (2011)

9927 Citations

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria.

Jan Pieter Abrahams;Andrew G. W. Leslie;René Lutter;René Lutter;John E. Walker.
Nature (1994)

3678 Citations

iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

T.G.G. Battye;L. Kontogiannis;O. Johnson;H.R. Powell.
Acta Crystallographica Section D-biological Crystallography (2011)

3576 Citations

The integration of macromolecular diffraction data

Andrew G. W. Leslie.
Acta Crystallographica Section D-biological Crystallography (1999)

1860 Citations

Structure of a beta1-adrenergic G-protein-coupled receptor.

Tony Warne;Maria J. Serrano-Vega;Jillian G. Baker;Rouslan Moukhametzianov.
Nature (2008)

1716 Citations

Molecular architecture of the rotary motor in ATP synthase

Daniela Stock;Andrew G. W. Leslie;John E. Walker.
Science (1999)

1519 Citations

Methods used in the structure determination of bovine mitochondrial F1 ATPase.

J.P. Abrahams;A.G.W. Leslie.
Acta Crystallographica Section D-biological Crystallography (1996)

1500 Citations

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

Guillaume Lebon;Tony Warne;Patricia C. Edwards;Kirstie A. Bennett.
Nature (2011)

863 Citations

The Crystal Structure of the Human Hepatitis B Virus Capsid

S.A Wynne;R.A Crowther;A.G.W Leslie.
Molecular Cell (1999)

777 Citations

Processing diffraction data with mosflm

Andrew G. W. Leslie;Harold R. Powell.
NATO Advanced Science Institutes (ASI) Series B (2007)

768 Citations

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