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Molecular Biology

D-Index
58
Citations
10913
World Ranking
2098
National Ranking
142

Overview

Manfred Frasch is affiliated with the University of Erlangen-Nuremberg in Germany. Their research spans the field of Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology, Cellular and Molecular Neuroscience, Immunology, Insect Science, and Biomaterials.

Their recent research outputs include papers published between 2021 and 2024. Selected publications are:

  • "Screens in fly and beetle reveal vastly divergent gene sets required for developmental processes" (2022, BMC Biology)
  • "Longitudinal visceral muscles in Drosophila fully dedifferentiate and fragment prior to their reestablishment during metamorphosis" (2023, PubMed)
  • "From promoter motif to cardiac function: a single DPE motif affects transcription regulation and organ function in vivo" (2024, Development)
  • "Large portion of essential genes is missed by screening either fly or beetle indicating unexpected diversity of insect gene function" (2021, bioRxiv (Cold Spring Harbor Laboratory))
  • "The RNF220 domain nuclear factor Teyrha-Meyrha (Tey) regulates the migration and differentiation of specific visceral and somatic muscles inDrosophila" (2022, bioRxiv (Cold Spring Harbor Laboratory))

Frequent coauthors include:

  • Dorothea Schultheis
  • Muhammad Salim Hakeemi
  • Salim Ansari
  • Matthias Teuscher
  • Matthias Weißkopf

The primary venues featuring their research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Development
  • BMC Biology
  • PubMed
  • Journal of Cell Science

Research topics addressed by Manfred Frasch include:

  • Neurobiology and Insect Physiology Research
  • Invertebrate Immune Response Mechanisms
  • Insect Utilization and Effects
  • Insect Resistance and Genetics
  • Congenital heart defects research
  • Genomics and Chromatin Dynamics
  • Silk-based biomaterials and applications

Best Publications

  • tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila.

    N Azpiazu;M Frasch

  • Characterization and localization of the even-skipped protein of Drosophila.

    M. Frasch;T. Hoey;C. Rushlow;H. Doyle

  • Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo

    Manfred Frasch

  • Early Signals in Cardiac Development

    Stéphane Zaffran;Manfred Frasch

  • The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.

    R. Fernandez;D. Tabarini;N. Azpiazu;M. Frasch

  • Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2.

    Maarten van Lohuizen;Manfred Frasch;Manfred Frasch;Ellen Wientjens;Anton Berns

  • Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila.

    M Frasch;M Levine

  • Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm.

    Xiaolei Xu;Zhizhang Yin;John B. Hudson;Edwin L. Ferguson

  • A new Drosophila homeo box gene is expressed in mesodermal precursor cells of distinct muscles during embryogenesis.

    Cord Dohrmann;Natalia Azpiazu;Manfred Frasch

  • Segmentation and specification of the Drosophila mesoderm.

    Natalia Azpiazu;Peter A. Lawrence;Jean-Paul Vincent;Manfred Frasch

  • Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila.

    M. Frasch;Xiaowei Chen;T. Lufkin

  • Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development

    Zhizhang Yin;Xiao Lei Xu;Manfred Frasch

  • Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers

    Hsiu-Hsiang Lee;Audra Norris;Joseph B. Weiss;Manfred Frasch

  • A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila.

    Patrick C.H Lo;Manfred Frasch

  • pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos

    Angelike Stathopoulos;Bergin Tam;Matthew Ronshaugen;Manfred Frasch

  • Maternal regulation of zerknüllt: a homoeobox gene controlling differentiation of dorsal tissues in Drosophila

    Christine Rushlow;Manfred Frasch;Helen Doyle;Michael Steven Levine

  • biniou (FoxF), a central component in a regulatory network controlling visceral mesoderm development and midgut morphogenesis in Drosophila

    Stephane Zaffran;Axel Küchler;Hsiu-Hsiang Lee;Manfred Frasch

  • The role of the NK-homeobox gene slouch (S59) in somatic muscle patterning

    Stefan Knirr;Natalia Azpiazu;Manfred Frasch

  • Cloning of a gene encoding an antigen associated with the centrosome in Drosophila.

    W. G. F. Whitfield;S. E. Millar;H. Saumweber;M. Frasch

  • Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 l

    Manfred Frasch;X. Chen;Thomas Lufkin

Frequent Co-Authors

Michael S. Levine
Michael S. Levine Princeton University
Thomas Lufkin
Thomas Lufkin Clarkson University
Rolf Bodmer
Rolf Bodmer Discovery Institute
Bruce M. Paterson
Bruce M. Paterson National Institutes of Health
David M. Glover
David M. Glover California Institute of Technology
Siegfried Roth
Siegfried Roth University of Cologne
Werner Risau
Werner Risau Max Planck Society
Mario Stanke
Mario Stanke University of Greifswald
Anton Berns
Anton Berns Antoni van Leeuwenhoek Hospital

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