Akinori Takaoka

Overview

Best Publications

• IRF-7 is the master regulator of type-I interferon-dependent immune responses

  Kenya Honda;Hideyuki Yanai;Hideo Negishi;Masataka Asagiri

  2782
  Citations

• DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

  Akinori Takaoka;Zhichao Wang;Myoung Kwon Choi;Hideyuki Yanai

  2088
  Citations

• Type I Inteferon Gene Induction by the Interferon Regulatory Factor Family of Transcription Factors

  Kenya Honda;Akinori Takaoka;Tadatsugu Taniguchi

  1694
  Citations

• T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma.

  Hiroshi Takayanagi;Kouetsu Ogasawara;Shigeaki Hida;Tomoki Chiba

  1564
  Citations

• Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

  Akinori Takaoka;Hideyuki Yanai;Seiji Kondo;Gordon Duncan

  1262
  Citations

• Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.

  Kenya Honda;Yusuke Ohba;Yusuke Ohba;Hideyuki Yanai;Hideo Negishi

  1139
  Citations

• Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

  Akinori Takaoka;Sumio Hayakawa;Hideyuki Yanai;Dagmar Stoiber;Dagmar Stoiber

  1105
  Citations

• Comparing antibody and small-molecule therapies for cancer

  Kohzoh Imai;Akinori Takaoka

  1057
  Citations

• Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

  Shigeki Chiba;Muhammad Baghdadi;Hisaya Akiba;Hironori Yoshiyama

  910
  Citations

• Interferon signalling network in innate defence.

  Akinori Takaoka;Hideyuki Yanai

  794
  Citations

• The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors.

  Tadatsugu Taniguchi;Akinori Takaoka

  695
  Citations

• Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

  Kenya Honda;Hideyuki Yanai;Tatsuaki Mizutani;Hideo Negishi

  685
  Citations

• A weak signal for strong responses: interferon-alpha/beta revisited.

  Tadatsugu Taniguchi;Akinori Takaoka

  654
  Citations

• Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

  Masahisa Jinushi;Shigeki Chiba;Hironori Yoshiyama;Kenkichi Masutomi

  623
  Citations

• Negative regulation of Toll-like-receptor signaling by IRF-4

  Hideo Negishi;Yusuke Ohba;Hideyuki Yanai;Akinori Takaoka

  479
  Citations

• Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection

  Kenya Honda;Shinya Sakaguchi;Chigusa Nakajima;Ai Watanabe

  472
  Citations

• The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus

  Seiichi Sato;Kai Li;Takeshi Kameyama;Takaya Hayashi

  459
  Citations

• Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.

  ZhiChao Wang;Myoung Kwon Choi;Tatsuma Ban;Hideyuki Yanai

  457
  Citations

• Cross Talk Between Interferon-γ and -α/β Signaling Components in Caveolar Membrane Domains

  Akinori Takaoka;Yukiko Mitani;Hirofumi Suemori;Mitsuharu Sato

  452
  Citations

• Integral role of Noxa in p53-mediated apoptotic response

  Tsukasa Shibue;Kiyoshi Takeda;Eri Oda;Hiroshi Tanaka

  434
  Citations