What is he best known for?
The fields of study he is best known for:
Toshiya Hirayama mainly investigates Molecular biology, Transfection, Biochemistry, Helicobacter pylori and Microbiology.
His Molecular biology research is multidisciplinary, incorporating elements of Secretion, Phospholipase C, Phosphorylation, Internalization and PI3K/AKT/mTOR pathway.
Toshiya Hirayama has researched Transfection in several fields, including Protein structure, GSK3B and Complementary DNA.
His work on In vitro, Phosphatase, Protein tyrosine phosphatase and Oligopeptide as part of general Biochemistry study is frequently linked to Peanut agglutinin, bridging the gap between disciplines.
His Helicobacter pylori study integrates concerns from other disciplines, such as CagA, Immunology and Tyrosine phosphorylation.
His study of Antimicrobial peptides is a part of Microbiology.
His most cited work include:
- β-Defensin-2 Expression Is Regulated by TLR Signaling in Intestinal Epithelial Cells (302 citations)
- In vitro gene transfection using dendritic poly(L-lysine) (228 citations)
- Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori (224 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Microbiology, Molecular biology, Helicobacter pylori, Biochemistry and Immunology.
The concepts of his Microbiology study are interwoven with issues in Pseudomonas aeruginosa, Receptor, Vibrio cholerae and Virulence.
Toshiya Hirayama combines subjects such as Cell culture, Transfection, HeLa, Mutant and Intracellular with his study of Molecular biology.
His Transfection research integrates issues from DNA, Phosphorylation and Antimicrobial peptides.
His Helicobacter pylori research incorporates elements of Inflammation, CagA and Secretion.
His work on Peptide, Protein tyrosine phosphatase, Amino acid and Ganglioside as part of general Biochemistry research is frequently linked to Amphiphile, bridging the gap between disciplines.
He most often published in these fields:
- Microbiology (32.80%)
- Molecular biology (32.80%)
- Helicobacter pylori (32.00%)
What were the highlights of his more recent work (between 2011-2019)?
- Helicobacter pylori (32.00%)
- Autophagy (4.80%)
- CagA (11.20%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Helicobacter pylori, Autophagy, CagA, Immunology and Apoptosis.
His Helicobacter pylori research incorporates themes from Proinflammatory cytokine, Lung, A549 cell and Microbiology.
Within one scientific family, Toshiya Hirayama focuses on topics pertaining to Virulence under Microbiology, and may sometimes address concerns connected to Salmonella enterica and Enterotoxin.
His CagA study also includes
- Phosphorylation which intersects with area such as Helicobacter pylori infection, Gene and Transfection,
- Cancer research which intersects with area such as Receptor, Protein tyrosine phosphatase and Phosphatase,
- Secretion that intertwine with fields like Cancer, CD44, Cancer stem cell and Reactive oxygen species.
He interconnects Signal transduction and Mitochondrion in the investigation of issues within Immunology.
Toshiya Hirayama has researched Apoptosis in several fields, including Toxin, Endoplasmic reticulum and Molecular biology.
Between 2011 and 2019, his most popular works were:
- Reactive Oxygen Species-Induced Autophagic Degradation of Helicobacter pylori CagA Is Specifically Suppressed in Cancer Stem-like Cells (153 citations)
- Low-density Lipoprotein Receptor-related Protein-1 (LRP1) Mediates Autophagy and Apoptosis Caused by Helicobacter pylori VacA (90 citations)
- Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis (44 citations)
In his most recent research, the most cited papers focused on:
Molecular biology, Apoptosis, Programmed cell death, Autophagy and Immunology are his primary areas of study.
The Molecular biology study combines topics in areas such as Virulence factor, Virulence, Periplasmic space, Mutant and Salmonella enterica.
His research in Apoptosis intersects with topics in Cell surface receptor, Receptor and Cell biology.
His studies deal with areas such as Unfolded protein response, Endoplasmic reticulum, Signal transduction and Mitochondrion as well as Programmed cell death.
His Inflammation study frequently draws parallels with other fields, such as Helicobacter pylori.
His Helicobacter pylori research is multidisciplinary, incorporating elements of Tumor necrosis factor alpha, CagA, Cancer, Reactive oxygen species and Microbiology.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
