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D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
41649
World Ranking
8429
National Ranking
560

Overview

Tomoki Chiba is affiliated with the University of Tsukuba in Japan. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on Molecular Biology, Cancer Research, and Immunology. Additional subfields include Orthopedics and Sports Medicine as well as Surgery.

The scientist's research interests cover diverse main topics such as RNA modifications and cancer, RNA research and splicing, tendon structure and treatment, ubiquitin and proteasome pathways, immune response and inflammation, cancer-related molecular mechanisms research, and immune cells in cancer.

Tomoki Chiba has contributed to several publications appearing in notable venues. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Cell and Developmental Biology, FEBS Letters, Journal of Bone and Mineral Metabolism, and International Journal of Molecular Sciences.

Selected recent papers authored or coauthored by Tomoki Chiba are:

  • Cartilage Homeostasis and Osteoarthritis, 2022, International Journal of Molecular Sciences
  • The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performance, 2022, Science Translational Medicine
  • Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice, 2022, Nature Communications
  • In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System, 2020, Frontiers in Cell and Developmental Biology
  • The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA, 2020, The EMBO Journal

Frequent coauthors collaborating with Tomoki Chiba include Hiroshi Asahara, Ryota Kurimoto, Takahide Matsushima, Y. Uchida, and Fuminori Tsuruta.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • AN NRF2/SMALL MAF HETERODIMER MEDIATES THE INDUCTION OF PHASE II DETOXIFYING ENZYME GENES THROUGH ANTIOXIDANT RESPONSE ELEMENTS

    Ken Itoh;Tomoki Chiba;Satoru Takahashi;Tetsuro Ishii

  • Loss of autophagy in the central nervous system causes neurodegeneration in mice

    Masaaki Komatsu;Satoshi Waguri;Satoshi Waguri;Tomoki Chiba;Shigeo Murata

  • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

    Hideki Shimura;Nobutaka Hattori;Shin-ichiro Kubo;Yoshikuni Mizuno

  • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

    Masaaki Komatsu;Satoshi Waguri;Takashi Ueno;Junichi Iwata

  • Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

    Akira Kobayashi;Moon Il Kang;Hiromi Okawa;Makiko Ohtsuji

  • T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma.

    Hiroshi Takayanagi;Kouetsu Ogasawara;Shigeaki Hida;Tomoki Chiba

  • Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

    Takanori Ebisawa;Minoru Fukuchi;Gyo Murakami;Tomoki Chiba

  • Dioxin receptor is a ligand-dependent E3 ubiquitin ligase

    Fumiaki Ohtake;Atsushi Baba;Ichiro Takada;Maiko Okada

  • CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein.

    Shigeo Murata;Yasufumi Minami;Michiko Minami;Tomoki Chiba

  • E3 ubiquitin ligase that recognizes sugar chains

    Yukiko Yoshida;Tomoki Chiba;Fuminori Tokunaga;Hiroshi Kawasaki

  • Covalent modification of all members of human cullin family proteins by NEDD8.

    Tomoko Hori;Fumio Osaka;Tomoki Chiba;Chikara Miyamoto

  • A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier

    Masaaki Komatsu;Tomoki Chiba;Kanako Tatsumi;Shun-ichiro Iemura

  • NEDD8 recruits E2-ubiquitin to SCF E3 ligase

    Takayuki Kawakami;Tomoki Chiba;Toshiaki Suzuki;Kazuhiro Iwai

  • A new NEDD8-ligating system for cullin-4A

    Fumio Osaka;Hiroshi Kawasaki;Noriko Aida;Mihoro Saeki

  • Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis

    Min Xian Qian;Ye Pang;Cui Hua Liu;Cui Hua Liu;Kousuke Haratake

  • Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins.

    Minoru Fukuchi;Takeshi Imamura;Tomoki Chiba;Takanori Ebisawa

  • The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

    Keisuke Tateishi;Masao Omata;Keiji Tanaka;Tomoki Chiba

  • Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

    Fumio Osaka;Mihoro Saeki;Satoshi Katayama;Noriko Aida

  • Excess peroxisomes are degraded by autophagic machinery in mammals.

    Jun Ichi Iwata;Junji Ezaki;Masaaki Komatsu;Masaaki Komatsu;Sadaki Yokota

Frequent Co-Authors

Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Shigeo Murata
Shigeo Murata University of Tokyo
Nobutaka Hattori
Nobutaka Hattori Juntendo University
Kazuhiro Iwai
Kazuhiro Iwai Kyoto University
Masaaki Komatsu
Masaaki Komatsu Juntendo University
Yoshikuni Mizuno
Yoshikuni Mizuno Juntendo University
Kohei Miyazono
Kohei Miyazono University of Tokyo
Koichi Kato
Koichi Kato National Institutes of Natural Sciences
Isei Tanida
Isei Tanida Juntendo University
Eiki Kominami
Eiki Kominami Juntendo University

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