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Genetics

D-Index
41
Citations
11042
World Ranking
4323
National Ranking
105

Overview

Silvia K. Nicolis is affiliated with the University of Milano-Bicocca in Italy. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a total of 43 publications. Within this broad field, their work focuses particularly on Molecular Biology, Cancer Research, Genetics, Oncology, and Cellular and Molecular Neuroscience.

The scientist's research topics cover several key areas including RNA Research and Splicing, MicroRNA in disease regulation, Genomics and Chromatin Dynamics, Pluripotent Stem Cells Research, Congenital heart defects research, Single-cell and spatial transcriptomics, and Cancer Cells and Metastasis.

Recent publications involve contributions to notable journals with topics addressing gene regulation, stem cell biology, and neural development. Selected papers include:

  • Sox2 Controls Neural Stem Cell Self-Renewal Through a Fos-Centered Gene Regulatory Network, 2021, Stem Cells
  • Deconstructing Sox2 Function in Brain Development and Disease, 2022, Cells
  • Structural basis for nuclear import selectivity of pioneer transcription factor SOX2, 2021, Nature Communications
  • SoxD genes are required for adult neural stem cell activation, 2022, Cell Reports
  • An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development, 2021, Open Biology

Frequent coauthors who have collaborated with Silvia K. Nicolis include:

  • Sara Mercurio
  • Miriam Pagin
  • Sergio Ottolenghi
  • Giulio Pavesi
  • Claudio Cantù

Publication venues where their work has often appeared include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cells
  • International Journal of Molecular Sciences
  • Zenodo (CERN European Organization for Nuclear Research)
  • Stem Cells

Best Publications

  • Multipotent cell lineages in early mouse development depend on SOX2 function

    Ariel A. Avilion;Silvia K. Nicolis;Larysa H. Pevny;Lidia Perez

  • Circular transcripts of the testis-determining gene Sry in adult mouse testis

    Blanche Capel;Amanda Swain;Silvia Nicolis;Adam Hacker

  • Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain.

    Anna L. M. Ferri;Maurizio Cavallaro;Daniela Braida;Antonello Di Cristofano

  • Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

    Rebecca Favaro;Menella Valotta;Anna L M Ferri;Elisa Latorre

  • Chromatin connectivity maps reveal dynamic promoter–enhancer long-range associations

    Yubo Zhang;Chee-Hong Wong;Ramon Y. Birnbaum;Guoliang Li

  • Sox2 roles in neural stem cells

    Larysa H. Pevny;Silvia K. Nicolis

  • Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells.

    M.V. Zappone;R. Galli;R. Catena;N. Meani

  • Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants

    Maurizio Cavallaro;Jessica Mariani;Cesare Lancini;Elisa Latorre

  • Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2.

    Eric T. Domyan;Elisabetta Ferretti;Kurt Throckmorton;Yuji Mishina

  • Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.

    Raffaella Catena;Cecilia Tiveron;Antonella Ronchi;Silvia Porta

  • Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest

    Igor Adameyko;Francois Lallemend;Alessandro Furlan;Nikolay Zinin

  • Cancer stem cells and "stemness" genes in neuro-oncology.

    Silvia K. Nicolis

  • Sox2 in the dermal papilla niche controls hair growth by fine-tuning Bmp signaling in differentiating hair shaft progenitors

    Carlos Clavel;Laura Grisanti;Roland Zemla;Amelie Rezza

  • A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

    Alessia Gagliardi;Nicholas P Mullin;Zi Ying Tan;Douglas Colby

  • Essential role of Sox2 for the establishment and maintenance of the germ cell line.

    Federica Campolo;Manuele Gori;Rebecca Favaro;Silvia Nicolis

  • Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells

    Evan S Bardot;Victor J Valdes;Jisheng Zhang;Carolina N Perdigoto

  • UFD1L, a Developmentally Expressed Ubiquitination Gene, is Deleted in CATCH 22 Syndrome

    Antonio Pizzuti;Giuseppe Novelli;Antonia Ratti;Francesca Amati

  • The transcription factor Sox2 is required for osteoblast self-renewal

    Upal Basu-Roy;Davide Ambrosetti;Rebecca Favaro;Silvia K. Nicolis

  • The effects of HPFH mutations in the human γ-globin promoter on binding of ubiquitous and erythroid specific nuclear factors

    R. Mantovani;N. Malgaretti;S. Nicolis;A. Ronchi

  • Sox2 is required to maintain cancer stem cells in a mouse model of high-grade oligodendroglioma

    Rebecca Favaro;Irene Appolloni;Serena Pellegatta;Alexandra Badiola Sanga

Frequent Co-Authors

Sergio Ottolenghi
Sergio Ottolenghi University of Milano-Bicocca
Roberto Mantovani
Roberto Mantovani University of Milan
Chia-Lin Wei
Chia-Lin Wei Lawrence Berkeley National Laboratory
Giovanni Migliaccio
Giovanni Migliaccio University of Washington
Anna Rita Migliaccio
Anna Rita Migliaccio University of Bologna
John W. Adamson
John W. Adamson University of California, San Diego
Robin Lovell-Badge
Robin Lovell-Badge The Francis Crick Institute
Paola Bovolenta
Paola Bovolenta Spanish National Research Council
Gaetano Finocchiaro
Gaetano Finocchiaro Istituto Neurologico Carlo Besta
Carolina Frassoni
Carolina Frassoni Istituto Neurologico Carlo Besta

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