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Noel F. Lowndes

Noel F. Lowndes

D-Index & Metrics

Biology and Biochemistry

D-Index
43
Citations
8472
World Ranking
19376
National Ranking
80

Research.com Recognitions

  • 2017 - Member of the Royal Irish Academy
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Noel F. Lowndes is affiliated with the National University of Ireland, Galway, and conducts research primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their work extensively covers Molecular Biology, with additional contributions to Public Health, Environmental and Occupational Health, Cell Biology, Oncology, and Genetics.

The researcher's investigations focus mainly on DNA Repair Mechanisms, which make up a significant portion of their publications. Other key topics include DNA and Nucleic Acid Chemistry, Nuclear Structure and Function, RNA Research and Splicing, CRISPR and Genetic Engineering, Acute Lymphoblastic Leukemia research, and Microtubule and mitosis dynamics.

Notable recent papers authored or co-authored by Lowndes include:

  • Immediate-Early, Early, and Late Responses to DNA Double Stranded Breaks (2022) - Frontiers in Genetics
  • The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair (2021) - Cell Reports
  • DDX17 is required for efficient DSB repair at DNA:RNA hybrid deficient loci (2022) - Nucleic Acids Research
  • Novel Pt(IV) Prodrugs Displaying Antimitochondrial Effects (2020) - Molecular Pharmaceutics
  • A function for ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission (2022) - iScience

Frequent co-authors collaborating with Lowndes include:

  • Janna Luessing
  • Aldo S. Bader
  • Ben R Hawley
  • George Skalka
  • Wei-Ting Lu

The researcher has published in various respected venues, such as Frontiers in Genetics, Cell Reports, Nucleic Acids Research, Molecular Pharmaceutics, and iScience.

Recognition for Lowndes's scientific contributions includes memberships in distinguished organizations like the Royal Irish Academy since 2017 and the European Molecular Biology Organization (EMBO).

Best Publications

  • A role for Saccharomyces cerevisiae histone H2A in DNA repair

    Jessica A. Downs;Noel F. Lowndes;Stephen P. Jackson;Stephen P. Jackson

  • Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

    Christopher S Gilbert;Catherine M Green;Noel F Lowndes;Noel F Lowndes

  • The MRN complex: coordinating and mediating the response to broken chromosomes

    Michael van den Bosch;Ronan T Bree;Noel F Lowndes

  • The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage.

    Jorge E. Vialard;Christopher S. Gilbert;Catherine M. Green;Noel F. Lowndes

  • Sensing and responding to DNA damage.

    Noel F Lowndes;Jose R Murguia

  • Control of DNA Synthesis Genes in Fission Yeast by the Cell-Cycle Gene cdc10+

    Lowndes Nf;McInerny Cj;Johnson Al;Fantes Pa

  • Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage

    Christophe Redon;Duane R Pilch;Emmy P Rogakou;Ann H Orr

  • A novel Rad24 checkpoint protein complex closely related to replication factor C.

    Catherine M. Green;Hediye Erdjument-Bromage;Paul Tempst;Noel F. Lowndes

  • Coordination of expression of DNA synthesis genes in budding yeast by a cell-cycle regulated trans factor.

    Noel F. Lowndes;Anthony L. Johnson;Leland H. Johnston

  • DNA repair: from molecular mechanism to human disease.

    Errol C. Friedberg;Andres Aguilera;Martin Gellert;Phillip C. Hanawalt

  • Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

    Muriel Grenon;Chris Gilbert;Noel F. Lowndes;Noel F. Lowndes

  • DNA Repair: The Importance of Phosphorylating Histone H2AX

    Noel F. Lowndes;Geraldine W.-L. Toh

  • SWI6 protein is required for transcription of the periodically expressed DNA synthesis genes in budding yeast

    Noel F. Lowndes;Anthony L. Johnson;Linda Breeden;Leland H. Johnston

  • RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation

    Maria‐Angeles de la Torre‐Ruiz;Catherine M. Green;Noel F. Lowndes

  • 53BP1: function and mechanisms of focal recruitment.

    Jennifer E. FitzGerald;Muriel Grenon;Noel F. Lowndes

  • Cell cycle control of DNA synthesis in budding yeast.

    Leland H. Johnston;Noel F. Lowndes

  • Modification of Histones by Sugar β-N-Acetylglucosamine (GlcNAc) Occurs on Multiple Residues, Including Histone H3 Serine 10, and Is Cell Cycle-regulated

    Suisheng Zhang;Kevin Roche;Heinz-Peter Nasheuer;Noel Francis Lowndes

  • Eukaryotic DNA damage checkpoint activation in response to double-strand breaks

    Karen Finn;Noel Francis Lowndes;Muriel Grenon

  • Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation

    Geraldine W.-L. Toh;Aisling M. O'Shaughnessy;Sonia Jimeno;Ian M. Dobbie

  • Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks

    Kyoko Nakamura;Wataru Sakai;Wataru Sakai;Takuo Kawamoto;Ronan T. Bree

Frequent Co-Authors

Leland H. Johnston
Leland H. Johnston Medical Research Council
Stephen P. Jackson
Stephen P. Jackson University of Cambridge
David G. Schatz
David G. Schatz Yale University
S.B. Richard
S.B. Richard McGill University
Hediye Erdjument-Bromage
Hediye Erdjument-Bromage New York University
Paul Tempst
Paul Tempst Memorial Sloan Kettering Cancer Center
Shunichi Takeda
Shunichi Takeda Shenzhen University
Pierre Thibault
Pierre Thibault University of Montreal
Afshin Samali
Afshin Samali University of Galway
Leif A. Eriksson
Leif A. Eriksson University of Gothenburg

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