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S.B. Richard

S.B. Richard

D-Index & Metrics

Molecular Biology

D-Index
84
Citations
21524
World Ranking
881
National Ranking
27

Overview

S.B. Richard is affiliated with McGill University in Canada and specializes in Biochemistry, Genetics, and Molecular Biology, with a research focus predominantly in Molecular Biology. Their work also spans Oncology, Immunology, Cancer Research, and Neurology.

Their research topics include:

  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing
  • CAR-T cell therapy research
  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering

S.B. Richard has published extensively, with a significant number of their papers appearing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, Nature Communications, Life Science Alliance, and Neuro-Oncology.

Frequent co-authors collaborating with S.B. Richard include Zhenbao Yu, Oscar D. Villarreal, Ting Cai, Dalia Baršytė-Lovejoy, and Claudia Dominici.

Selected recent publications by S.B. Richard include:

  • "Cellular pathways influenced by protein arginine methylation: Implications for cancer," 2021, Molecular Cell
  • "Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response," 2020, Nature Communications
  • "DDX5 resolves R-loops at DNA double-strand breaks to promote DNA repair and avoid chromosomal deletions," 2020, NAR Cancer
  • "Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication," 2021, Journal of Biological Chemistry
  • "Synergistic effects of type I PRMT and PARP inhibitors against non-small cell lung cancer cells," 2021, Clinical Epigenetics

Best Publications

  • Arginine methylation an emerging regulator of protein function.

    Mark T. Bedford;Stéphane Richard

  • Protein hydration in solution: Experimental observation by x-ray and neutron scattering

    D. I. Svergun;S. Richard;M. H. J. Koch;Z. Sayers

  • The regulation, functions and clinical relevance of arginine methylation.

    Ernesto Guccione;Stéphane Richard

  • A Proteomic Analysis of Arginine-methylated Protein Complexes

    François-Michel Boisvert;Jocelyn Côté;Marie-Chloé Boulanger;Stéphane Richard

  • Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients

    Chantal Sellier;Frédérique Rau;Yilei Liu;Flora Tassone

  • RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

    Frédérick A Mallette;Frédérick A Mallette;Francesca Mattiroli;Gaofeng Cui;Leah C Young

  • Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products

    Tomohisa Kuzuyama;Joseph P. Noel;Stéphane B. Richard

  • Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains

    Mark T. Bedford;Adam Frankel;Michael B. Yaffe;Steven Clarke

  • Sam68 RNA Binding Protein Is an In Vivo Substrate for Protein Arginine N-Methyltransferase 1

    Jocelyn Côté;François Michel Boisvert;Marie Chloé Boulanger;Mark T. Bedford

  • Emerging Roles of Disordered Sequences in RNA-Binding Proteins.

    Sara Calabretta;Stéphane Richard

  • Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs

    Surbhi Dhar;Vidyasiri Vemulapalli;Alexander N. Patananan;Grace L. Huang

  • Arginine Methylation of the Histone H3 Tail Impedes Effector Binding

    Aimee N. Iberg;Alexsandra Espejo;Donghang Cheng;Daehoon Kim

  • Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control.

    François-Michel Boisvert;Ugo Déry;Jean-Yves Masson;Stéphane Richard

  • Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations

    Miranda L. Tradewell;Zhenbao Yu;Zhenbao Yu;Michael Tibshirani;Marie-Chloé Boulanger;Marie-Chloé Boulanger

  • Self-Association of the Single-KH-Domain Family Members Sam68, GRP33, GLD-1, and Qk1: Role of the KH Domain

    Taiping Chen;Bassam B. Damaj;Constance Herrera;Paul Lasko

  • Methylation of Tat by PRMT6 Regulates Human Immunodeficiency Virus Type 1 Gene Expression

    Marie Chloé Boulanger;Chen Liang;Rodney S. Russell;Rongtuan Lin

  • A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation.

    Zhenbao Yu;Taiping Chen;Josée Hébert;En Li

  • Nuclear Retention of MBP mRNAs in the Quaking Viable Mice

    Daniel Larocque;Julie Pilotte;Taiping Chen;Frank Cloutier

  • A protein-domain microarray identifies novel protein-protein interactions.

    Alexsandra Espejo;Jocelyn Côté;Andrzej Bednarek;Stephane Richard

  • Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing

    François-Michel Boisvert;Jocelyn Côté;Marie-Chloé Boulanger;Patrick Cléroux

Frequent Co-Authors

Joseph P. Noel
Joseph P. Noel Salk Institute for Biological Studies
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Taiping Chen
Taiping Chen The University of Texas MD Anderson Cancer Center
Guillermina Almazan
Guillermina Almazan McGill University
Jean-Yves Masson
Jean-Yves Masson Université Laval
Tomohisa Kuzuyama
Tomohisa Kuzuyama University of Tokyo
Paul Lasko
Paul Lasko McGill University
Mark T. Bedford
Mark T. Bedford The University of Texas MD Anderson Cancer Center
John K. Heath
John K. Heath University of Birmingham
Ivan Topisirovic
Ivan Topisirovic McGill University

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