Naoki Okada

Overview

Best Publications

• Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch.

  Sachiko Hirobe;Hiroaki Azukizawa;Takaaki Hanafusa;Kazuhiko Matsuo

  279
  Citations

• Chitosan capsules for colon-specific drug delivery: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats

  Hideyuki Tozaki;Tomokazu Odoriba;Naoki Okada;Takuya Fujita

  259
  Citations

• Modulation of Intestinal P-Glycoprotein Function by Cremophor EL and Other Surfactants by an In Vitro Diffusion Chamber Method Using the Isolated Rat Intestinal Membranes

  Yasushi Shono;Hisayo Nishihara;Yasuyuki Matsuda;Shiori Furukawa

  222
  Citations

• Enhanced Permeability of Insulin across the Rat Intestinal Membrane by Various Absorption Enhancers: Their Intestinal Mucosal Toxicity and Absorption‐enhancing Mechanism of n‐Lauryl‐β‐D‐maltopyranoside

  Tomomi Uchiyama;Tetsuo Sugiyama;Ying‐Shu Quan;Atsushi Kotani

  206
  Citations

• The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1β production, ROS production and endosomal rupture

  Tomohiro Morishige;Yasuo Yoshioka;Hiroshi Inakura;Aya Tanabe

  200
  Citations

• Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies.

  Qi Shen;Yulian Lin;Takahiro Handa;Masamichi Doi

  179
  Citations

• Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza.

  Kazuhiko Matsuo;Sachiko Hirobe;Yayoi Yokota;Yurika Ayabe

  171
  Citations

• A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens

  Kazuhiko Matsuo;Yayoi Yokota;You Zhai;Ying-Shu Quan

  158
  Citations

• Effects of Labrasol and other pharmaceutical excipients on the intestinal transport and absorption of rhodamine123, a P-glycoprotein substrate, in rats.

  Yulian Lin;Yulian Lin;Qi Shen;Hidemasa Katsumi;Naoki Okada

  149
  Citations

• Efficient Antigen Gene Transduction Using Arg-Gly-Asp Fiber-Mutant Adenovirus Vectors Can Potentiate Antitumor Vaccine Efficacy and Maturation of Murine Dendritic Cells

  Naoki Okada;Tomomi Saito;Yasushige Masunaga;Yukiko Tsukada

  138
  Citations

• Development and clinical study of a self-dissolving microneedle patch for transcutaneous immunization device.

  Sachiko Hirobe;Hiroaki Azukizawa;Kazuhiko Matsuo;You Zhai

  135
  Citations

• Titanium dioxide induces different levels of IL-1β production dependent on its particle characteristics through caspase-1 activation mediated by reactive oxygen species and cathepsin B

  Tomohiro Morishige;Yasuo Yoshioka;Aya Tanabe;Xinglei Yao

  130
  Citations

• Role of MyD88 and TLR9 in the innate immune response elicited by serotype 5 adenoviral vectors.

  Tomoko Yamaguchi;Kenji Kawabata;Naoya Koizumi;Fuminori Sakurai

  127
  Citations

• Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration

  Jian-Qing Gao;Yusuke Eto;Yasuo Yoshioka;Fumiko Sekiguchi

  126
  Citations

• Nanoparticles built by self-assembly of amphiphilic γ-PGA can deliver antigens to antigen-presenting cells with high efficiency : A new tumor-vaccine carrier for eliciting effector T cells

  Tomoaki Yoshikawa;Naoki Okada;Atsushi Oda;Keisuke Matsuo

  121
  Citations

• Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold.

  Kento Fujiwara;Ayaka Tsunei;Hotaka Kusabuka;Erika Ogaki

  118
  Citations

• Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors.

  Naoki Okada;Yukiko Tsukada;Shinsaku Nakagawa;Hiroyuki Mizuguchi

  116
  Citations

• Performance and characteristics evaluation of a sodium hyaluronate-based microneedle patch for a transcutaneous drug delivery system.

  Yasuhiro Hiraishi;Takeshi Nakagawa;Ying-Shu Quan;Fumio Kamiyama

  114
  Citations

• Functional and molecular identification of sodium-coupled dicarboxylate transporters in rat primary cultured cerebrocortical astrocytes and neurons.

  Etsuo Yodoya;Miyuki Wada;Ayumi Shimada;Hiromi Katsukawa

  110
  Citations

• A novel strategy utilizing ultrasound for antigen delivery in dendritic cell-based cancer immunotherapy.

  Ryo Suzuki;Yusuke Oda;Naoki Utoguchi;Eisuke Namai

  108
  Citations