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Molecular Biology

D-Index
69
Citations
15157
World Ranking
1482
National Ranking
752

Overview

Takao Hayakawa is a researcher affiliated with the National Institutes of Health in the United States. Their primary fields of study include Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on Molecular Biology and Genetics. The research spans into subfields such as Radiology, Nuclear Medicine and Imaging, Spectroscopy, and Surgery.

The scientist's research covers topics including Mesenchymal stem cell research, Glycosylation and Glycoproteins Research, Monoclonal and Polyclonal Antibodies Research, Analytical Chemistry and Chromatography, Pancreatic function and diabetes, Pluripotent Stem Cells Research, and Microbial infections and disease research.

Takao Hayakawa has published work in several scientific venues. Frequent publication venues include:

  • Journal of Chromatography A
  • PubMed
  • Journal of Artificial Organs
  • Journal of Investigative Dermatology

Recent papers authored or co-authored by Takao Hayakawa demonstrate a range of research areas and methodologies:

  • Analysis of 2-aminopyridine labeled glycans by dual-mode online solid phase extraction for hydrophilic interaction and reversed-phase liquid chromatography, 2020, Journal of Chromatography A
  • Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System, 2022, PubMed
  • Rapid and sensitive mycoplasma detection system using image-based deep learning, 2021, Journal of Artificial Organs
  • FOXO3A Plays a Role in Wound Healing by Regulating Fibroblast Mitochondrial Dynamics, 2024, Journal of Investigative Dermatology

Collaborative efforts form an important aspect of Hayakawa's research. Frequent co-authors include:

  • Hiroyuki Moriyama
  • Mariko Moriyama
  • Kishimoto Yuka
  • Fuka Okada
  • Tomohiro Maesako

Takao Hayakawa's work integrates molecular techniques and analytical chemistry approaches, particularly within mesenchymal stem cell studies and glycosylation research. The intersection with clinical disease contexts, such as diabetes and microbial infections, underlines a multidisciplinary approach combining fundamental biology with applications in medicine.

Best Publications

  • IRES-Dependent Second Gene Expression Is Significantly Lower Than Cap-Dependent First Gene Expression in a Bicistronic Vector

    Hiroyuki Mizuguchi;Zhili Xu;Akiko Ishii-Watabe;Eriko Uchida

  • Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells.

    Akiko Eguchi;Teruo Akuta;Hajime Okuyama;Takao Senda

  • Activation of NADPH oxidase in Alzheimer's disease brains.

    Shun Shimohama;Hiroko Tanino;Naoko Kawakami;Naoki Okamura

  • Quantitative Comparison of Intracellular Trafficking and Nuclear Transcription between Adenoviral and Lipoplex Systems

    Susumu Hama;Hidetaka Akita;Rie Ito;Hiroyuki Mizuguchi

  • 3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing

    Kazuo Takayama;Kenji Kawabata;Yasuhito Nagamoto;Keisuke Kishimoto

  • A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob

    H Mizuguchi;N Koizumi;N Koizumi;T Hosono;N Utoguchi

  • Efficient Generation of Functional Hepatocytes From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells by HNF4α Transduction

    Kazuo Takayama;Mitsuru Inamura;Kenji Kawabata;Kazufumi Katayama

  • A novel PPARγ gene therapy to control inflammation associated with inflammatory bowel disease in a murine model

    Kazufumi Katayama;Koichiro Wada;Atsushi Nakajima;Hiroyuki Mizuguchi

  • A Novel Murine Model of Graves’ Hyperthyroidism with Intramuscular Injection of Adenovirus Expressing the Thyrotropin Receptor

    Yuji Nagayama;Masako Kita-Furuyama;Takao Ando;Kazuhiko Nakao

  • Optimization of transcriptional regulatory elements for constructing plasmid vectors.

    Zhi-Li Xu;Hiroyuki Mizuguchi;Akiko Ishii-Watabe;Eriko Uchida

  • Autoinhibitory Regulation of p73 by ΔNp73 To Modulate Cell Survival and Death through a p73-Specific Target Element within the ΔNp73 Promoter

    Takahito Nakagawa;Masato Takahashi;Toshinori Ozaki;Ken-ichi Watanabe

  • Targeted Adenovirus Vectors

    Hiroyuki Mizuguchi;Takao Hayakawa

  • Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells.

    Hong Xin;Masahiko Kanehira;Hiroyuki Mizuguchi;Takao Hayakawa

  • Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells

    M Kanehira;H Xin;K Hoshino;M Maemondo

  • A novel strategy for the enhancement of drug absorption using a claudin modulator.

    Masuo Kondoh;Akane Masuyama;Azusa Takahashi;Nagayoshi Asano

  • Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction

    Kazuo Takayama;Mitsuru Inamura;Kenji Kawabata;Michiko Sugawara

  • Adenovirus vectors containing chimeric type 5 and type 35 fiber proteins exhibit altered and expanded tropism and increase the size limit of foreign genes

    Hiroyuki Mizuguchi;Takao Hayakawa

  • Efficient Adipocyte and Osteoblast Differentiation from Mouse Induced Pluripotent Stem Cells by Adenoviral Transduction

    Katsuhisa Tashiro;Mitsuru Inamura;Kenji Kawabata;Fuminori Sakurai

  • Preparation of lactose-silk fibroin conjugates and their application as a scaffold for hepatocyte attachment.

    Yohko Gotoh;Shingo Niimi;Takao Hayakawa;Tokuji Miyashita

  • Generation of fiber‐modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob

    Naoya Koizumi;Hiroyuki Mizuguchi;Naoki Utoguchi;Yoshiteru Watanabe

Frequent Co-Authors

Hiroyuki Mizuguchi
Hiroyuki Mizuguchi Osaka University
Tadanori Mayumi
Tadanori Mayumi Kobe Gakuin University
Shinsaku Nakagawa
Shinsaku Nakagawa Osaka University
Naoki Okada
Naoki Okada Osaka University
Kazuaki Kakehi
Kazuaki Kakehi Kindai University
Takuya Fujita
Takuya Fujita Ritsumeikan University
Kazuhide Inoue
Kazuhide Inoue Kyushu University
Takashi Nakayama
Takashi Nakayama Kindai University
Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Masami Niwa
Masami Niwa Nagasaki University

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