World's Best Scientists 2026 revealed!
Shinsaku Nakagawa

Shinsaku Nakagawa

D-Index & Metrics

Immunology

D-Index
67
Citations
12135
World Ranking
2710
National Ranking
111

Overview

Shinsaku Nakagawa is affiliated with Osaka University in Japan, contributing primarily to the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research outputs focus on subfields including Molecular Biology, Cellular and Molecular Neuroscience, Food Science, Pathology and Forensic Medicine, and Pharmacology.

The scientist's work encompasses a range of topics such as:

  • Tea Polyphenols and Effects
  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Ion Channels and Receptors
  • Seaweed-derived Bioactive Compounds
  • Neuropeptides and Animal Physiology
  • Receptor Mechanisms and Signaling

Notable recent publications include:

  • (S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression, 2020, Pharmacology Biochemistry and Behavior
  • A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke, 2021, Nature Communications
  • Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like Properties, 2022, ACS Medicinal Chemistry Letters
  • Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion, 2022, Frontiers in Nutrition
  • Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism, 2020, Frontiers in Neuroscience

The scientist frequently collaborates with several researchers, including:

  • Yukio Ago
  • Kenji Ishimoto
  • Nobumasa Hino
  • Tatsunori Miyaoka
  • Hitoshi Hashimoto

Their work has been published in various scientific venues, notably:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • YAKUGAKU ZASSHI
  • Pharmacology Biochemistry and Behavior
  • Nature Communications
  • ACS Medicinal Chemistry Letters

Best Publications

  • Solution of the structure of the TNF-TNFR2 complex

    Y. Mukai;T. Nakamura;M. Yoshikawa;Y. Yoshioka

  • Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch.

    Sachiko Hirobe;Hiroaki Azukizawa;Takaaki Hanafusa;Kazuhiko Matsuo

  • Site-specific PEGylation of a lysine-deficient TNF-α with full bioactivity

    Yoko Yamamoto;Yasuo Tsutsumi;Yasuo Yoshioka;Toshihide Nishibata

  • Cancer gene therapy by IL-12 gene delivery using liposomal bubbles and tumoral ultrasound exposure

    Ryo Suzuki;Eisuke Namai;Yusuke Oda;Norihito Nishiie

  • A novel PPARγ gene therapy to control inflammation associated with inflammatory bowel disease in a murine model

    Kazufumi Katayama;Koichiro Wada;Atsushi Nakajima;Hiroyuki Mizuguchi

  • Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins.

    Tsuyoshi Nakanishi;Jun Kunisawa;Akira Hayashi;Yasuo Tsutsumi

  • The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1β production, ROS production and endosomal rupture

    Tomohiro Morishige;Yasuo Yoshioka;Hiroshi Inakura;Aya Tanabe

  • Innate immune response induced by gene delivery vectors

    Haruna Sakurai;Kenji Kawabata;Fuminori Sakurai;Shinsaku Nakagawa

  • Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza.

    Kazuhiko Matsuo;Sachiko Hirobe;Yayoi Yokota;Yurika Ayabe

  • A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens

    Kazuhiko Matsuo;Yayoi Yokota;You Zhai;Ying-Shu Quan

  • Antitumor Activity of Tumor Necrosis Factor-α Conjugated with Polyvinylpyrrolidone on Solid Tumors in Mice

    Haruhiko Kamada;Yasuo Tsutsumi;Yoko Yamamoto;Tetsunari Kihira

  • Creation and X-ray Structure Analysis of the Tumor Necrosis Factor Receptor-1-selective Mutant of a Tumor Necrosis Factor-α Antagonist

    Hiroko Shibata;Yasuo Yoshioka;Akiko Ohkawa;Kyoko Minowa

  • PEGylated adenovirus vectors containing RGD peptides on the tip of PEG show high transduction efficiency and antibody evasion ability.

    Yusuke Eto;Jian-Qing Gao;Jian-Qing Gao;Fumiko Sekiguchi;Shinnosuke Kurachi

  • Efficient Antigen Gene Transduction Using Arg-Gly-Asp Fiber-Mutant Adenovirus Vectors Can Potentiate Antitumor Vaccine Efficacy and Maturation of Murine Dendritic Cells

    Naoki Okada;Tomomi Saito;Yasushige Masunaga;Yukiko Tsukada

  • Development and clinical study of a self-dissolving microneedle patch for transcutaneous immunization device.

    Sachiko Hirobe;Hiroaki Azukizawa;Kazuhiko Matsuo;You Zhai

  • Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release.

    Jun Kunisawa;Takashi Masuda;Kazufumi Katayama;Tomoaki Yoshikawa

  • Titanium dioxide induces different levels of IL-1β production dependent on its particle characteristics through caspase-1 activation mediated by reactive oxygen species and cathepsin B

    Tomohiro Morishige;Yasuo Yoshioka;Aya Tanabe;Xinglei Yao

  • Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration

    Jian-Qing Gao;Yusuke Eto;Yasuo Yoshioka;Fumiko Sekiguchi

  • Nanoparticles built by self-assembly of amphiphilic γ-PGA can deliver antigens to antigen-presenting cells with high efficiency : A new tumor-vaccine carrier for eliciting effector T cells

    Tomoaki Yoshikawa;Naoki Okada;Atsushi Oda;Keisuke Matsuo

  • Intravenous Administration of Polyethylene Glycol-Coated (PEGylated) Proteins and PEGylated Adenovirus Elicits an Anti-PEG Immunoglobulin M Response

    Taro Shimizu;Masako Ichihara;Yasuo Yoshioka;Tatsuhiro Ishida

  • Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors.

    Naoki Okada;Yukiko Tsukada;Shinsaku Nakagawa;Hiroyuki Mizuguchi

  • Efficient Gene Transfer into Mammalian Cells Using Fusogenic Liposome

    Hiroyuki Mizuguchi;Tetsuhiko Nakagawa;Mahito Nakanishi;Mahito Nakanishi;Susumu Imazu

  • Functionalization of Tumor Necrosis Factor-α Using Phage Display Technique and PEGylation Improves Its Antitumor Therapeutic Window

    Hiroko Shibata;Yasuo Yoshioka;Shinji Ikemizu;Kyoko Kobayashi

Frequent Co-Authors

Tadanori Mayumi
Tadanori Mayumi Kobe Gakuin University
Naoki Okada
Naoki Okada Osaka University
Hiroyuki Mizuguchi
Hiroyuki Mizuguchi Osaka University
Takao Hayakawa
Takao Hayakawa National Institutes of Health
Takuya Fujita
Takuya Fujita Ritsumeikan University
Yoshiyuki Ohsugi
Yoshiyuki Ohsugi Roche (Switzerland)
Yuriko Yamagata
Yuriko Yamagata Kumamoto University
Mitsuru Akashi
Mitsuru Akashi Osaka University
Isao Kitagawa
Isao Kitagawa Osaka University
Motomasa Kobayashi
Motomasa Kobayashi Osaka University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Immunology in the USA opens doors to a variety of health-focused careers, many of which intersect with nursing and advanced practice roles. For those interested in mental health, exploring the cheapest pmhnp programs online can be a cost-effective way to advance a career in psychiatric nursing, integrating immunological knowledge with mental health care.

Further educational advancement, such as earning a Doctorate in Nursing Practice (DNP), often leads to higher salaries and greater clinical responsibilities. The comprehensive data on doctorate in nursing salary highlights the financial benefits of such degrees across various states.

Immunology professionals aiming to transition into more specialized roles may consider acute care nurse practitioner programs. These programs offer targeted training for managing complex immune-related conditions in acute care settings.

For those seeking accelerated paths, particularly nursing professionals entering immunology fields, the accelerated np program options provide streamlined routes to becoming nurse practitioners, balancing speed with quality education.

Overall, combining immunology studies with nursing and advanced practice degrees can pave the way for a dynamic and impactful healthcare career.

Best Scientists Citing Shinsaku Nakagawa

Trending Scientists