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Margaret E. Ackerman

Margaret E. Ackerman

D-Index & Metrics

Immunology

D-Index
52
Citations
9889
World Ranking
4062
National Ranking
1852

Overview

Margaret E. Ackerman is a researcher primarily affiliated with Dartmouth College in the United States. Their scholarly work spans multiple fields within medicine and immunology, with a particular focus on infectious diseases, immune responses, and vaccine-related research.

Their main fields of study include Medicine with 227 publications and Immunology and Microbiology with 124 publications. Specific subfields of emphasis include Infectious Diseases, Immunology, Radiology, Nuclear Medicine and Imaging, Virology, and Molecular Biology.

Key research topics covered by their publications are:

  • Monoclonal and Polyclonal Antibodies Research
  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • COVID-19 Clinical Research Studies
  • Vaccines and Immunoinformatics Approaches

Margaret E. Ackerman has contributed to numerous academic articles, with a number of frequently cited papers including:

  • "Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination" (2020) in Science Translational Medicine
  • "Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals" (2021) in Frontiers in Immunology
  • "Antibody-mediated complement activation in pathology and protection" (2020) in Immunology and Cell Biology
  • "Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality" (2021) in Journal of Clinical Investigation
  • "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody" (2020) in Proceedings of the National Academy of Sciences

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • PLoS Pathogens
  • The Journal of Infectious Diseases
  • Vaccine

The scientist has collaborated extensively with several co-authors, with the most frequent partners being:

  • Joshua A. Weiner
  • Arnaud Marchant
  • Peter F. Wright
  • Harini Natarajan
  • Wendy Wieland-Alter

In addition to articles, Margaret E. Ackerman has contributed to book publications, including a volume titled Fc-Mediated Antibody Functions and Fc-Receptor Polymorphism Volume II published by Frontiers Media in 2023.

Best Publications

  • A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

    Margaret E. Ackerman;Brian Moldt;Richard T. Wyatt;Anne-Sophie Dugast

  • Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines

    Amy W. Chung;Musie Ghebremichael;Hannah Robinson;Eric Brown

  • Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

    Margaret E. Ackerman;Matthew Crispin;Xiaojie Yu;Kavitha Baruah

  • Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.

    Amy W. Chung;Amy W. Chung;Manu P. Kumar;Kelly B. Arnold;Wen Han Yu;Wen Han Yu

  • Protective Efficacy of Adenovirus/Protein Vaccines Against SIV Challenges in Rhesus Monkeys

    Dan H. Barouch;Dan H. Barouch;Galit Alter;Thomas Broge;Caitlyn Linde

  • Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control

    Margaret E. Ackerman;Anastassia Mikhailova;Eric P. Brown;Karen G. Dowell

  • High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples

    Eric P. Brown;Anna F. Licht;Anne-Sophie Dugast;Ickwon Choi

  • Adjuvant-dependent Innate and Adaptive Immune Signatures of Risk of SIVmac251 Acquisition

    Monica Vaccari;Shari N Gordon;Slim Fourati;Luca Schifanella;Luca Schifanella

  • Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles.

    Eric P. Brown;Karen G. Dowell;Austin W. Boesch;Erica Normandin

  • A modular IgG-scFv bispecific antibody topology

    Kelly Davis Orcutt;Margaret E. Ackerman;Maryelise Cieslewicz;Emmanuel Quiroz

  • Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

    Margaret E. Ackerman;Jishnu Das;Srivamshi Pittala;Thomas Broge

  • Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

    Todd Bradley;Justin Pollara;Sampa Santra;Nathan Vandergrift

  • Protein-Protein Fusion Catalyzed by Sortase A

    David A. Levary;Ranganath Parthasarathy;Eric T. Boder;Margaret E. Ackerman

  • Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination

    Todd J. Suscovich;Jonathan K. Fallon;Jishnu Das;Allison R. Demas;Allison R. Demas

  • Stability and CDR composition biases enrich binder functionality landscapes.

    Benjamin J. Hackel;Margaret E. Ackerman;Shanshan W. Howland;K. Dane Wittrup

  • Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination

    Unknown

  • Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids

    Margaret E. Ackerman;David Pawlowski;K. Dane Wittrup

  • Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function.

    Amy W. Chung;Max Crispin;Laura Pritchard;Hannah Robinson

  • Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals.

    Savannah E Butler;Andrew R Crowley;Harini Natarajan;Shiwei Xu

  • Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women

    David R. Martinez;Youyi Fong;Shuk Hang Li;Fang Yang

  • A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis.

    Alison E. Mahan;Jacquelynne Tedesco;Kendall Dionne;Kavitha Baruah

  • Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display.

    Margaret Ackerman;David Levary;Gabriel Tobon;Benjamin Hackel

  • Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b

    Margaret E. Ackerman;Anne-Sophie Dugast;Elizabeth G. McAndrew;Stephen Tsoukas

Frequent Co-Authors

Georgia D. Tomaras
Georgia D. Tomaras Duke University
Todd J. Suscovich
Todd J. Suscovich SeromYx Systems
Guido Ferrari
Guido Ferrari Duke University
Dan H. Barouch
Dan H. Barouch Harvard Medical School
Nelson L. Michael
Nelson L. Michael Walter Reed Army Institute of Research
Thomas C. Quinn
Thomas C. Quinn Johns Hopkins University
David C. Montefiori
David C. Montefiori Duke University
Jerome H. Kim
Jerome H. Kim Walter Reed Army Institute of Research
Oliver Laeyendecker
Oliver Laeyendecker Johns Hopkins University

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