Antony Rosen spends much of his time researching Cell biology, Immunology, Biochemistry, Apoptosis and Autoantibody. The concepts of his Cell biology study are interwoven with issues in Biological pathway and Caspase, Programmed cell death. His Caspase research includes themes of Proteases, Granzyme B and Proteolysis.
Immunology is closely attributed to Myositis in his work. His biological study spans a wide range of topics, including Receptor, Lipid raft, Cytoplasm and Colocalization. As a part of the same scientific family, Antony Rosen mostly works in the field of Autoantibody, focusing on Antigen and, on occasion, Mutated citrullinated vimentin, Internal medicine, Rheumatoid arthritis and Rheumatology.
Immunology, Autoantibody, Antibody, Autoimmunity and Apoptosis are his primary areas of study. In most of his Immunology studies, his work intersects topics such as Disease. His Autoantibody study incorporates themes from Myositis, Scleroderma, Pathology, Internal medicine and Dermatomyositis.
As part of one scientific family, Antony Rosen deals mainly with the area of Autoimmunity, narrowing it down to issues related to the Epitope, and often Antigen processing. His Apoptosis study integrates concerns from other disciplines, such as Proteases, Poly ADP ribose polymerase, Proteolysis and Cell biology. In his study, Lymphocyte is strongly linked to Cytotoxic T cell, which falls under the umbrella field of Cell biology.
His scientific interests lie mostly in Immunology, Autoantibody, Antibody, Scleroderma and Internal medicine. His Immunology research incorporates elements of Dermatomyositis and Disease. His Autoantibody research is multidisciplinary, relying on both Odds ratio, Immunohistochemistry, Disease pathogenesis, Systemic lupus erythematosus and Breast cancer.
His Epitope study in the realm of Antibody connects with subjects such as In patient. The Internal medicine study which covers Gastroenterology that intersects with Confidence interval and Interquartile range. His studies deal with areas such as Cancer research, Antigen and Cell biology as well as Immune system.
His primary scientific interests are in Immunology, Autoimmunity, Autoantibody, Antibody and Scleroderma. His work on Immune system, Epitope and Autoimmune disease as part of general Immunology study is frequently linked to Citrullination, therefore connecting diverse disciplines of science. His Autoimmunity study also includes
His work in Autoantibody addresses subjects such as Internal medicine, which are connected to disciplines such as Gastroenterology. His Antibody study combines topics from a wide range of disciplines, such as Interferon, Pathogenesis and Interstitial lung disease. While the research belongs to areas of Scleroderma, Antony Rosen spends his time largely on the problem of Cancer, intersecting his research to questions surrounding RNA polymerase III and Lung cancer.
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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.
L A Casciola-Rosen;G Anhalt;A Rosen.
Journal of Experimental Medicine (1994)
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.
Livia Casciola-Rosen;Donald W. Nicholson;Tae Chong;Kevin R. Rowan.
Journal of Experimental Medicine (1996)
Autoantibodies against 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase in patients with statin‐associated autoimmune myopathy
Andrew L Mammen;Tae Chung;Lisa Christopher-Stine;Paul Rosen.
Arthritis & Rheumatism (2011)
Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity
Livia Casciola-Rosen;Felipe Andrade;Danielle Ulanet;Wes Bang Wong.
Journal of Experimental Medicine (1999)
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus.
Livia Casciola-Rosen;Antony Rosen;Michelle Petri;Mark Schlissel.
Proceedings of the National Academy of Sciences of the United States of America (1996)
The Caspase-3 Precursor Has a Cytosolic and Mitochondrial Distribution: Implications for Apoptotic Signaling
Marie Mancini;Donald W. Nicholson;Sophie Roy;Nancy A. Thornberry.
Journal of Cell Biology (1998)
DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis.
Livia A. Casciola-Rosen;Grant J. Anhalt;Antony Rosen.
Journal of Experimental Medicine (1995)
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset.
Raphaela Goldbach-Mansky;Jennifer Lee;Angela McCoy;Joseph Hoxworth.
Arthritis Research (2000)
Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death.
Livia A. Casciola-Rosen;Douglas K. Miller;Grant J. Anhalt;Antony Rosen.
Journal of Biological Chemistry (1994)
Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis
Marie Mancini;Carolyn E. Machamer;Sophie Roy;Donald W. Nicholson.
Journal of Cell Biology (2000)
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