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John H. Wolfe

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10883
World Ranking
13914
National Ranking
5880

John H. Wolfe publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John H. Wolfe sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 155 publications — 29th percentile

29% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John H. Wolfe D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John H. Wolfe sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 57 D-Index — 31st percentile

31% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

John H. Wolfe is affiliated with the University of Pennsylvania in the United States. Their research spans several interconnected fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. Within these broader areas, they have contributed extensively to Molecular Biology, Genetics, Cellular and Molecular Neuroscience, Epidemiology, and Physiology.

The scientist's work focuses on several main topics, notably virus-based gene therapy research, retinal development and disorders, herpesvirus infections and treatments, and lysosomal storage disorders research. Additional research interests include neuroscience and neural engineering, photoreceptor and optogenetics research, and cytomegalovirus and herpesvirus research.

Recent publications from John H. Wolfe illustrate a focus on gene therapy and neural research. These include:

  • Intracisternal vs intraventricular injection of AAV1 result in comparable, widespread transduction of the dog brain (2024, Gene Therapy)
  • Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs (2022, Stem Cell Reports)
  • Transduction characteristics of alternative adeno-associated virus serotypes in the cat brain by intracisternal delivery (2022, Molecular Therapy - Methods & Clinical Development)
  • Islet1 Precursors Contribute to Mature Interneuron Subtypes in Mouse Neocortex (2021, Cerebral Cortex)
  • Global CNS correction in a large brain model of human alpha-mannosidosis by intravascular gene therapy (2020, Brain)

John H. Wolfe frequently publishes in several scientific venues, among which Molecular Therapy - Methods & Clinical Development features prominently with three publications. Other venues include Stem Cell Reports, Brain, Cerebral Cortex, and Gene Therapy.

Collaboration is a significant aspect of their research approach. Frequent coauthors include Jacqueline E. Hunter, Caitlyn Molony, Charles H. Vite, Sanjeev Chawla, and Patricia A. O'Donnell, with the highest coauthor count being five shared papers each with Jacqueline E. Hunter and Caitlyn Molony.

Best Publications

  • Engraftable human neural stem cells respond to development cues, replaceneurons, and express foreign genes

    Jonathan D. Flax;Sanjay Aurora;Chunhua Yang;Clemence Simonin

  • Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain.

    Evan Y. Snyder;Rosanne M. Taylor;Rosanne M. Taylor;John H. Wolfe

  • Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain.

    Cassia N. Cearley;John H. Wolfe

  • Intraventricular Brain Injection of Adeno-Associated Virus Type 1 (AAV1) in Neonatal Mice Results in Complementary Patterns of Neuronal Transduction to AAV2 and Total Long-Term Correction of Storage Lesions in the Brains of β-Glucuronidase-Deficient Mice

    Marco A. Passini;Deborah J. Watson;Charles H. Vite;Daniel J. Landsburg

  • Targeted Transduction Patterns in the Mouse Brain by Lentivirus Vectors Pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV Envelope Proteins

    Deborah J. Watson;Deborah J. Watson;Gary P. Kobinger;Marco A. Passini;Marco A. Passini;James M. Wilson

  • A single injection of an adeno-associated virus vector into nuclei with divergent connections results in widespread vector distribution in the brain and global correction of a neurogenetic disease.

    Cassia N Cearley;John H Wolfe

  • Progress in gene therapy for neurological disorders

    Michele Simonato;Jean Bennett;Nicholas M. Boulis;Maria G. Castro

  • Dosage Thresholds for AAV2 and AAV8 Photoreceptor Gene Therapy in Monkey

    Luk H. Vandenberghe;Peter Bell;Albert M. Maguire;Albert M. Maguire;Cassia N. Cearley;Cassia N. Cearley

  • Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer.

    John H. Wolfe;Mark S. Sands;Jane E. Barker;Babette Gwynn

  • Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration.

    Danielle Emille Mor;Elpida Tsika;Joseph R Mazzulli;Neal S Gould

  • Herpesvirus vector gene transfer and expression of β–glucuronidase in the central nervous system of MRS VII mice

    John H. Wolfe;Satish L. Deshmane;Nigel W. Fraser

  • Widespread Gene Delivery and Structure-Specific Patterns of Expression in the Brain after Intraventricular Injections of Neonatal Mice with an Adeno-Associated Virus Vector

    Marco A. Passini;John H. Wolfe

  • Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs

    Katherine Parker Ponder;John R Melniczek;Lingfei Xu;Margaret A Weil

  • Sustained Production of β-Glucuronidase from Localized Sites after AAV Vector Gene Transfer Results in Widespread Distribution of Enzyme and Reversal of Lysosomal Storage Lesions in a Large Volume of Brain in Mucopolysaccharidosis VII Mice

    Annette F. Skorupa;Krisna J. Fisher;James M. Wilson;Michael K. Parente

  • Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.

    Cassia N Cearley;Luk H Vandenberghe;Michael K Parente;Michael K Parente;Erin R Carnish;Erin R Carnish

  • Decreased lysosomal storage in the adult MPS VII mouse brain in the vicinity of grafts of retroviral vector-corrected fibroblasts secreting high levels of beta-glucuronidase.

    Rosanne M Taylor;John H Wolfe

  • Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy.

    YogendraSinh H Raol;Ingrid V Lund;Sabita Bandyopadhyay;Guojun Zhang

  • Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport.

    Michael J. Castle;Zachary T. Gershenson;April R. Giles;Erika L.F. Holzbaur

  • Distribution of a Lysosomal Enzyme in the Adult Brain by Axonal Transport and by Cells of the Rostral Migratory Stream

    Marco A. Passini;Edward B. Lee;Gregory G. Heuer;John H. Wolfe

  • Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids

    Michael J. Castle;Michael J. Castle;Heikki T. Turunen;Luk H. Vandenberghe;John H. Wolfe;John H. Wolfe

Frequent Co-Authors

Nigel W. Fraser
Nigel W. Fraser University of Pennsylvania
Luk H. Vandenberghe
Luk H. Vandenberghe Massachusetts Eye and Ear Infirmary
Gustavo D. Aguirre
Gustavo D. Aguirre University of Pennsylvania
James M. Wilson
James M. Wilson University of Pennsylvania
L. A. Frank
L. A. Frank University of Iowa
Rita J. Valentino
Rita J. Valentino National Institute on Drug Abuse
Jean Bennett
Jean Bennett University of Pennsylvania
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
Joseph C. Glorioso
Joseph C. Glorioso University of Pittsburgh

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Related Online Degrees & Career Pathways

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Best Scientists Citing John H. Wolfe

Evan Y. Snyder

Evan Y. Snyder

Discovery Institute

Publications: 132

Seung U. Kim

Seung U. Kim

University of British Columbia

Publications: 116

Mark S. Sands

Mark S. Sands

Washington University in St. Louis

Publications: 54

Yang D. Teng

Yang D. Teng

Spaulding Rehabilitation Hospital

Publications: 48

Miguel Sena-Esteves

Miguel Sena-Esteves

University of Massachusetts Chan Medical School

Publications: 46

Karl Deisseroth

Karl Deisseroth

Stanford University

Publications: 41

James M. Wilson

James M. Wilson

University of Pennsylvania

Publications: 40

Beverly L. Davidson

Beverly L. Davidson

Children's Hospital of Philadelphia

Publications: 35

John J. Hopwood

John J. Hopwood

University of Adelaide

Publications: 35

Guangping Gao

Guangping Gao

University of Massachusetts Chan Medical School

Publications: 25

Xandra O. Breakefield

Xandra O. Breakefield

Harvard University

Publications: 24

Richard L. Sidman

Richard L. Sidman

Harvard University

Publications: 24

Steven A. Goldman

Steven A. Goldman

University of Rochester Medical Center

Publications: 24

Ronald G. Crystal

Ronald G. Crystal

Cornell University

Publications: 24

Manho Kim

Manho Kim

Seoul National University Hospital

Publications: 23

Philippe Moullier

Philippe Moullier

University of Nantes

Publications: 22

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